Genetic influences on alcohol flushing in East Asian populations by Cho, Y, Lin, K, Lee, S-H, Yu, C, Valle, DS, Avery, D, Lv, J, Jung, K, Li, L, Smith, GD, Chen, Z, Sun, D, Millwood, IY, Hemani, G, Walters, RG

“…</p> <p><strong>Results</strong></p> <p>We identified variants in the region of <i>ALDH2</i> strongly associated with alcohol flushing, replicating previous studies conducted in East Asian populations. Additionally, we identified variants in the alcohol dehydrogenase 1B (<i>ADH1B</i>) gene region associated with alcohol flushing. …”

Adherence to healthy lifestyle and cardiovascular diseases in the Chinese population by Lv, J, Yu, C, Guo, Y, Bian, Z, Yang, L, Chen, Y, Tang, X, Zhang, W, Qian, Y, Huang, Y, Wang, X, Chen, J, Chen, Z, Qi, L, Li, L, China Kadoorie Biobank Collaborative Group

“…BACKGROUND: Adherence to a combination of healthy lifestyle factors has been related to a considerable reduction of cardiovascular risk in white populations; however, little is known whether such associations persist in nonwhite populations like the Asian population. …”

Genetic influences on alcohol flushing in East Asian populations by Cho, Y, Lin, K, Lee, S-H, Yu, C, Valle, DS, Avery, D, Lv, J, Jung, K, Li, L, Smith, GD, Chen, Z, Millwood, I, Hemani, G, Walters, R

“…</p> <p><strong>Results</strong> We identified variants in the region of <i>ALDH2</i> strongly associated with alcohol flushing, replicating previous studies conducted in East Asian populations. Additionally, we identified variants in the alcohol dehydrogenase 1B (<i>ADH1B</i>) gene region associated with alcohol flushing. …”

Tea consumption and bone health in Chinese adults: a population-based study by Li, X, Qiao, Y, Yu, C, Guo, Y, Bian, Z, Yang, L, Chen, Y, Yan, S, Xie, X, Huang, D, Chen, J, Chen, Z, Lv, J, Li, L, China Kadoorie Biobank Collaborative Group

“…The sex-specific associations are unrevealed among general population. This study showed that prolonged moderate tea consumption benefited bone health in women, while no additional benefit with stronger tea. …”

Dementia and hospital admission post-TIA and stroke: longitudinal population-based study by Pendlebury, ST, Luengo-Fernandez, R, McColl, AJ, Rothwell, PM, Li, L

Risk of recurrent stroke in patients with intracranial stenosis: a population based study by Hurford, R, Wolters, FJ, Li, L, Kuker, W, Rothwell, PM

Prognostic value of "tissue-based" definitions of TIA and minor stroke: population-based study by Hurford, R, Li, L, Lovett, N, Kubiak, M, Kuker, W, Rothwell, P, Oxford Vascular Study

“…</p> <p><strong>METHODS:</strong> Consecutive eligible patients with TIA or minor stroke (NIH Stroke Scale [NIHSS] ≤3) in the population-based Oxford Vascular Study underwent brain MRI at baseline. …”

Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study by Sun, Q, Yu, D, Fan, J, Yu, C, Guo, Y, Pei, P, Yang, L, Chen, Y, Du, H, Yang, X, Sansome, S, Wang, Y, Zhao, W, Chen, J, Chen, Z, Zhao, L, Lv, J, Li, L

“…Interpretation Our findings suggest that increasing the adoption of these five healthy lifestyle factors through public health interventions could be associated with substantial gains in life expectancy in the Chinese population.…”

Age- and sex-specific rates of leukoaraiosis in TIA and stroke patients: population-based study. by Simoni, M, Li, L, Paul, N, Gruter, B, Schulz, U, Küker, W, Rothwell, P

“…OBJECTIVE: To determine any sex differences in age-specific prevalence or severity of leukoaraiosis, a marker of white matter ischemia, in population-based and clinic cohorts of TIA/stroke and in a systematic review of the literature. …”

PCSK9 genetic variants and risk of vascular and non-vascular diseases in Chinese and UK populations by Holmes, M, Kartsonaki, C, Boxall, R, Lin, K, Reeve, N, Yu, C, Lv, J, Bennett, D, Hill, MR, Yang, L, Chen, Y, Du, H, Turnbull, I, Collins, R, Clarke, RJ, Tobin, MD, Li, L, Millwood, IY, Chen, Z, Walters, RG

Social inequalities in low birth weight in England and Wales: trends and implications for future population health. by Moser, K, Li, L, Power, C

Causal association between snoring and stroke: a Mendelian randomization study in a Chinese population by Zhu, Y, Zhuang, Z, Lv, J, Sun, D, Pei, P, Yang, L, Chen, Z, Millwood, IY, Walters, RG, Chen, Y, Du, H, Wu, X, Schmidt, D, Avery, D, Chen, J, Li, L, Yu, C

Time-course of blood pressure control prior to lacunar TIA and stroke: population-based study by Li, L, Welch, S, Gutnikov, S, Mehta, Z, Rothwell, P

“…</p> <h4>Methods</h4> <p>In a population-based study of TIA/ischaemic stroke (Oxford Vascular Study), we studied 15-year premorbid BP readings from primary care records in patients with lacunar vs. non-lacunar events (TOAST) stratified by age (<!…”

PROGNOSTIC VALUE OF WHITE MATTER CHANGES IN PATIENTS WITH TIA OR STROKE: A POPULATION-BASED STUDY by Simoni, M, Li, L, Mehta, Z, Rothwell, P

Associations of blood biomarkers with glomerular filtration rate in patients with TIA and stroke: population-based study by Kelly, DM, Li, L, Burgess, AI, Poole, DL, Duerden, JM, Rothwell, PM

“…<br> <strong>Methods</strong> We studied a panel of 16 blood biomarkers related to inflammation, thrombosis, atherogenesis and cardiac or neuronal cell damage in TIA or ischaemic stroke in a population-based study (Oxford Vascular Study). Biomarker levels were log-transformed and correlated with eGFR, adjusted for age. …”

Season and outdoor temperature in relation to detection and control of hypertension in a large rural Chinese population. by Su, D, Du, H, Zhang, X, Qian, Y, Chen, L, Chen, Y, Guo, Y, Bian, Z, Chen, Z, Li, L, Yu, M

“…BACKGROUND: In many Western populations, blood pressure varies moderately with season and outdoor temperature. …”

The hospitalization burden of all-cause pneumonia in China: a population-based study, 2009–2017 by Hu, Y, Han, Y, Yu, C, Guo, Y, Pei, P, Yang, L, Chen, Y, Du, H, Sun, D, Pang, Y, Niu, W, Burgess, S, Hacker, A, Chen, J, Chen, Z, Lv, J, Li, L

“…Generalized linear models were used to examine the secular trends and regional and population variations in pneumonia hospitalization rate, mean length of hospital stay (LOS), and 30-day case fatality rate (CFR). …”

Genetic and healthy lifestyle factors in relation to the incidence and prognosis of severe liver disease in the Chinese population by Pang, Y, Lv, J, Kartsonaki, C, Yu, C, Guo, Y, Chen, Y, Yang, L, Millwood, IY, Walters, RG, Lv, S, Burgess, S, Sansome, S, Chen, J, Chen, Z, Li, L

“…</p> <p><strong>Methods:</strong> The study population included 504,009 participants from the prospective China Kadoorie Biobank aged 30–79 years. …”

Early data from the first population-wide breast cancer-specific registry in Hong Kong. by Cheung, P, Hung, W, Cheung, C, Chan, A, Wong, T, Li, L, Chan, S, Chan, K, Choi, P, Kwan, W, Yau, C, Chan, E, Law, S, Kwan, D

Proteomic aging clock predicts mortality and risk of common age-related diseases in diverse populations by Argentieri, MA, Xiao, S, Bennett, D, Winchester, L, Nevado-Holgado, AJ, Ghose, U, Albukhari, A, Yao, P, Mazidi, M, Lv, J, Millwood, I, Fry, H, Rodosthenous, RS, Partanen, J, Zheng, Z, Kurki, M, Daly, MJ, Palotie, A, Adams, CJ, Li, L, Clarke, R, Amin, N, Chen, Z, van Duijn, CM

“…Our results demonstrate that proteomic aging involves proteins spanning multiple functional categories and can be used to predict age-related functional status, multimorbidity and mortality risk across geographically and genetically diverse populations.…”