Combined Self-Assembled iRGD Polymersomes for Effective Targeted siRNA Anti-Tumor Therapy by Li D, Li J, Wang S, Teng W, Wang Q

“…Dongying Li,1,2,* Jiarun Li,1,2,* Siwei Wang,1,2 Wei Teng,2 Qinmei Wang1 1Laboratory of Biomaterials, Key Laboratory on Assisted Circulation, Ministry of Health, Cardiovascular Division, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China; 2Hospital of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Institute of Stomatological Research, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Teng; Qinmei Wang, Email tengwei@mail.sysu.edu.cn; wangqinm@mail.sysu.edu.cnIntroduction: iRGD is usually used as a motif to modify siRNA-nanodelivery vectors to improve tumor-targeting and penetration. …”
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Paracentral Acute Middle Maculopathy Following Acute Primary Angle Closure and Acute Primary Angle Closure Glaucoma by Xiao H, Guo N, Li J, Jin L, Liu Y, Lin S, Fang L, Liu X, Zuo C

“…Hui Xiao,* Ni Guo,* Junyi Li, Ling Jin, Yuan Liu, Shufen Lin, Lei Fang, Xing Liu, Chengguo Zuo State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xing Liu; Chengguo Zuo, Zhongshan Ophthalmic Center, Sun Yat-sen University, 7 Jinsui Road, Guangzhou, 510000, People’s Republic of China, Email liuxing@mail.sysu.edu.cn; zuochengguo@mail.sysu.edu.cnPurpose: To report the prevalence, clinical characteristics and risk factors for paracentral acute middle maculopathy (PAMM) following acute primary angle closure (APAC) and acute primary angle closure glaucoma (APACG).Methods: This retrospective study consecutively recruited patients diagnosed with APAC or APACG. …”
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The Effectiveness of Student-Led Ward Round Training on Knowledge Acquisition, Critical Thinking Ability, and Self-Confidence of Acute Upper Gastrointestinal Bleeding for Nursing S... by Liu N, Zheng Z, Liao J, Li J, Yang Z, Lai X

“…Nan Liu,* Ziyu Zheng,* Jinli Liao,* Jiaxin Li, Zhen Yang, Xiaojuan Lai Department of Emergency Medicine, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaojuan Lai; Zhen Yang, Email laixj3@mail.sysu.edu.cn; yangzh8@mail.sysu.edu.cnIntroduction: Nursing knowledge, critical thinking ability, and self-perceived confidence are imperative to nursing skills in professional nursing practice. …”
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Follistatin Alleviates Hepatic Steatosis in NAFLD via the mTOR Dependent Pathway by Tong J, Cong L, Jia Y, He BL, Guo Y, He J, Li D, Zou B, Li J

“…Junlu Tong1,2 *, Li Cong1 *, Yingbin Jia,3 Bai-Liang He,4 Yifan Guo,1 Jianzhong He,5 Decheng Li,3 Baojia Zou,3 Jian Li3 1Department of Endocrinology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China; 2Department of Central Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China; 3Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China; 4Guangdong Provincial Key Laboratory of Biomedical Imaging, Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China; 5Department of Pathology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian Li; Baojia Zou, Department of Hepatobiliary Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China, Tel +86-756-252-8781, Email lijian5@mail.sysu.edu.cn; zoubj6@mail.sysu.edu.cnPurpose: In this study, we aimed to investigate the effect of follistatin (FST) on hepatic steatosis in NAFLD and the underlying mechanism, which has rarely been reported before.Methods: Liver samples from NAFLD patients and normal liver samples (from liver donors) were collected to investigate hepatic FST expression in humans. …”
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Combined Treatment of Tanshinone I and Epirubicin Revealed Enhanced Inhibition of Hepatocellular Carcinoma by Targeting PI3K/AKT/HIF-1α by Zhao J, Lin E, Cai C, Zhang M, Li D, Cai S, Zeng G, Yin Z, Wang B, Li P, Hong X, Chen J, Zou B, Li J

“…Jiali Zhao,1 En Lin,1 Chaonong Cai,1 Manyao Zhang,2 Decheng Li,1 Shanglin Cai,1 Guifang Zeng,1 Zeren Yin,1 Bo Wang,1 Peiping Li,1 Xiaopeng Hong,1 Jiafan Chen,1 Baojia Zou,1 Jian Li1 1Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China; 2Department of Anesthesiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of ChinaCorrespondence: Jian Li; Baojia Zou, Department of Hepatobiliary Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, People’s Republic of China, Tel +86-756-252-8781, Fax +86-756-252-8166, Email lijian5@mail.sysu.edu.cn; zoubj6@mail.sysu.edu.cnBackground: Epirubicin (EADM) is a common chemotherapeutic agent in hepatocellular carcinoma (HCC). …”
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Enhancing Cutaneous Wound Healing Based on Human Induced Neural Stem Cell-derived Exosomes by Li J, Gao H, Xiong Y, Wang L, Zhang H, He F, Zhao J, Liu S, Gao L, Guo Y, Deng W

“…Jing Li,* Hong Gao,* Yue Xiong,* Ling Wang, Haojie Zhang, Fumei He, Jingxin Zhao, Shuna Liu, Liqian Gao, Ying Guo, Wenbin Deng School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-Sen University, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ying Guo; Wenbin Deng, Email guoying1226@hotmail.com; dengwb5@mail.sysu.edu.cnBackground: Wound healing of skin is a complicated process. …”
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Nonlinear Relationship Between Maternal and Cord Blood Vitamin B12 and Folate from a Chinese Population-Based Study by Du Y, Li J, Qu P, Dang S

“…Yujiao Du,1 Jing Li,1 Pengfei Qu,2 Shaonong Dang1 1Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, 710061, People’s Republic of China; 2Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an Jiaotong University Health Science Center, Xi’an, 710003, People’s Republic of ChinaCorrespondence: Shaonong Dang, Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, 710061, People’s Republic of China, Tel +86-13468779736, Fax +86-2982655730, Email tjdshn@mail.xjtu.edu.cnPurpose: There remains a data gap on vitamin B12 and folate level in maternal and child populations. …”
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Electroencephalography Theta/Beta Ratio Decreases in Patients with Severe Obstructive Sleep Apnea by Li J, You J, Yin G, Xu J, Zhang Y, Yuan X, Chen Q, Ye J

“…Jingjing Li,1 Jingyuan You,2 Guoping Yin,1 Jinkun Xu,1 Yuhuan Zhang,1 Xuemei Yuan,1 Qiang Chen,1 Jingying Ye1,3 1Department of Otorhinopharyngology–Head and Neck Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People’s Republic of China; 2Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, People’s Republic of China; 3Institute of Precision Medicine, Tsinghua University, Beijing, People’s Republic of ChinaCorrespondence: Jingying Ye, Department of Otorhinopharyngology–Head and Neck Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Litang Road 168, Beijing, 102218, People’s Republic of China, Tel +86-13701396970, Email yejingying@mail.tsinghua.edu.cnPurpose: Accumulating evidence suggests that theta/beta ratio (TBR), an electroencephalographic (EEG) frequency band parameter, might serve as an objective marker of executive cognitive control in healthy adults. …”
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Altered Functional Connectivity of Large-Scale Brain Networks in Psychogenic Erectile Dysfunction Associated with Cognitive Impairments by Feng S, Dong L, Yan B, Zheng S, Feng Z, Li X, Li J, Sun N, Ning Y, Jia H

“…Sitong Feng,1,2 Linrui Dong,1,2 Bin Yan,3 Sisi Zheng,1,2 Zhengtian Feng,1,2 Xue Li,1,2 Jiajia Li,1,2 Ning Sun,3 Yanzhe Ning,1,2 Hongxiao Jia1,2 1Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, People’s Republic of China; 3Department of Andrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of ChinaCorrespondence: Hongxiao Jia; Yanzhe Ning, Beijing Anding Hospital, Capital Medical University, No. 5 Ankang Hutong, Xicheng District, Beijing, 100088, People’s Republic of China, Tel +86 010-58303065, Email jhxlj@ccmu.edu.cn; ningzy0923@mail.ccmu.edu.cnPurpose: Several studies have demonstrated that psychogenic erectile dysfunction (pED) patients potentially suffer from cognitive dysfunction. …”
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Risk Factors and Prognostic Implications of New-Onset Paroxysmal Atrial Fibrillation in Patients Hospitalized with Intracerebral Hemorrhage by Huang B, Li J, Li P, Chen C, Cao S, Jiang Z, Zeng J

“…Baozi Huang,1,2 Jianle Li,1 Pingping Li,1,2 Chunyong Chen,1,2 Suhan Cao,1 Zimu Jiang,1 Jinsheng Zeng1 1Department of Neurology and Stroke Center, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, The First Affiliated Hospital, Sun Yat-sen University, National Key Clinical Department and Key Discipline of Neurology, Guangzhou, People’s Republic of China; 2Department of Neurology of the First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of ChinaCorrespondence: Jinsheng Zeng, Department of Neurology and Stroke Center, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, The First Affiliated Hospital, Sun Yat-sen University, National Key Clinical Department and Key Discipline of Neurology, No. 58 Zhongshan Road 2, Guangzhou, 510080, People’s Republic of China, Tel +86-20-87755766-8253, Fax +86-20-87335935, Email zengjsh@mail.sysu.edu.cnObjective: We aimed to assess the prevalence and risk factors of new-onset paroxysmal atrial fibrillation (PAF) in patients hospitalized with ICH and determine whether the new-onset PAF had influenced functional outcomes.Methods: We analyzed a database of all consecutive patients with ICH from October 2013 to May 2022. …”
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Neutrophil Percentage-to-Albumin Ratio and Risk of Mortality in Patients on Peritoneal Dialysis by Yu Y, Zhong Z, Yang W, Yu J, Li J, Guo X, Chen J, Mao H, Li Z

“…Yi Yu,1,2,* Zhong Zhong,1,2,* Wenzhuo Yang,1,2 Jianwen Yu,1,2 Jianbo Li,1,2 Xingdi Guo,1,2 Jiasi Chen,3 Haiping Mao,1,2 Zhijian Li1,2 1Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, People’s Republic of China; 2NHC Key Laboratory of Clinical Nephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, 510080, People’s Republic of China; 3Department of Nephrology, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510120, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhijian Li, Department of Nephrology, The First Affiliated Hospital, Sun Yat-Sen University, 58th Zhongshan Road II, Guangzhou, 510080, People’s Republic of China, Tel +8620 87335811, Fax +8620 87755766, Email lizhjian@mail.sysu.edu.cnBackground: Neutrophil percentage-to-albumin ratio (NPAR), a new inflammatory marker, has been shown to be associated with poor prognosis in patients with cardiovascular disease. …”
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Fungal Spectrum and Susceptibility Against Nine Antifungal Agents in 525 Deep Fungal Infected Cases by Cai W, Ruan Q, Li J, Lin L, Xi L, Sun J, Lu S

“…Wenying Cai,1,* Qianqian Ruan,2– 4,* Jiahao Li,1 Li Lin,1 Liyan Xi,1,5 Jiufeng Sun,2,3 Sha Lu1 1Department of Dermatology and Venereology, Sun Yat-sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Institute of Public Health, Guangzhou, People’s Republic of China; 3Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, People’s Republic of China; 4School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China; 5Dermatology Hospital, Southern Medical University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Sha Lu, Department of Dermatology and Venereology, Sun Yat-sen Memorial Hospital of Sun Yat-Sen University, 107 West Yanjiang Road, Guangzhou, People’s Republic of China, Email lush7@mail.sysu.edu.cn Jiufeng Sun, Guangdong Provincial Center for Disease Control and Prevention, 160 Qunxian Road, Guangzhou, People’s Republic of China, Email sunjiuf@163.comBackground: Deep fungal infection has become an important cause of infection and death in hospitalized patients, and this has worsened with increasing antifungal drug resistance.Objective: A 3-year retrospective study was conducted to investigate the clinical characteristics, pathogen spectrum, and drug resistance of deep fungal infection in a regional hospital of Guangzhou, China.Methods: Non-duplicate fungi isolates recovered from blood and other sterile body fluids of in-patients of the clinical department were identified using biochemical tests of pure culture with the API20C AUX and CHROMagar medium. …”
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