Myostatin: a potential therapeutic target for metabolic syndrome by Ming Yang, Ming Yang, Chongbin Liu, Chongbin Liu, Na Jiang, Na Jiang, Yan Liu, Yan Liu, Shilu Luo, Shilu Luo, Chenrui Li, Chenrui Li, Hao Zhao, Hao Zhao, Yachun Han, Yachun Han, Wei Chen, Wei Chen, Li Li, Li Li, Li Xiao, Li Xiao, Lin Sun, Lin Sun

“…Multiple studies have shown that myostatin (MSTN), a member of the TGF-β family, is involved in the development and development of obesity, hyperlipidemia, diabetes, and hypertension (clinical manifestations of metabolic syndrome), and thus may be a potential therapeutic target for metabolic syndrome. In this review, we describe the transcriptional regulation and receptor binding pathway of MSTN, then introduce the role of MSTN in regulating mitochondrial function and autophagy, review the research progress of MSTN in metabolic syndrome. …”
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The role and therapeutic potential of gut microbiome in severe burn by Zhijie Huang, Yisheng Huang, Jun Chen, Zhengming Tang, Yuanxin Chen, Hongyu Liu, Mingshu Huang, Ling Qing, Li Li, Qin Wang, Bo Jia

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Targeting iron-metabolism:a potential therapeutic strategy for pulmonary fibrosis by Yi Sun, Yu Ren, Li-yun Song, Yin-ying Wang, Tian-gang Li, Ying-li Wu, Li Li, Zhong-shan Yang

“…Targeting iron metabolism may be a potential therapeutic strategy for the prevention and treatment of pulmonary fibrosis.…”
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Application of nanomedicine in radiotherapy sensitization by Xiaoyu Song, Xiaoyu Song, Zhenkun Sun, Li Li, Lu Zhou, Shuanghu Yuan, Shuanghu Yuan, Shuanghu Yuan

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The NLRP3 inflammasome is a potential mechanism and therapeutic target for perioperative neurocognitive disorders by Jiayue Li, Li Li, Jiannan He, Jianhong Xu, Fangping Bao, Fangping Bao

“…The present review summarizes recent studies and systematically describes the pathogenesis of NLRP3 activation and regulation and potential therapeutics targeting NLRP3 inflammasomes in PNDs patients.…”
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Targeting interleukin 4 and interleukin 13: a novel therapeutic approach in bullous pemphigoid by Fangyuan Chen, Yiman Wang, Xinyi Chen, Nan Yang, Li Li

“…However, before this novel therapy can be approved for regular usage, further studies are needed concerning the long-term safety and systemic usage of IL-4/13 monoclonal antibody treatment in BP.KEY MESSAGESBP is an autoimmune skin disease with Th2-mediated autoimmune response involvement.As typical Th2 cytokines, IL-4 and IL-13 may contribute to the pathogenesis of BP in multiple ways, such as promoting Th2 cell polarization, driving the immunoglobulin class switching, recruiting eosinophils and basophils, and inducing pruritus.As a promising therapeutic approach for BP, IL-4/13 antagonists have shown satisfactory outcomes in preliminary clinical studies.…”
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Observation of the therapeutic effect of apatinib in advanced platinum-resistant recurrent epithelial ovarian cancer by Zhongmian Pan, Zhongbin Luo, Hongying He, Yujie Chen, Bingbing Zhao, Zhijun Yang, Li Li

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Metabolic rewiring in keratinocytes by miR‐31‐5p identifies therapeutic intervention for psoriasis by Mao‐Jie Wang, Huan‐Jie Huang, Yong‐Yue Xu, Harmjan Vos, Can Gulersonmez, Edwin Stigter, Johan Gerritsen, Marc Pages Gallego, Robert vanEs, Li Li, Hao Deng, Lin Han, Run‐Yue Huang, Chuan‐Jian Lu, Boudewijn MT Burgering

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TOMM34 serves as a candidate therapeutic target associated with immune cell infiltration in colon cancer by Zhigui Li, Hongzhao Yang, Jianbo Liu, Li Li, Xiaodong Wang

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Current insights on the roles of gut microbiota in inflammatory bowel disease-associated extra-intestinal manifestations: pathophysiology and therapeutic targets by Yizhe Tie, Yongle Huang, Rirong Chen, Li Li, Minhu Chen, Shenghong Zhang

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Quantitative proteomics reveals the therapeutic effects of RFAP against depression via pathway regulation of long-term depression and potentiation by Yang Wu, Ying Hao, Guohua Yu, Li Li, Shanglong Wang, Xin Li, Zengliang Zhang, Shengcan Zou, Zimin Liu, Pengcheng Fan, Yuanyuan Shi

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ARID1A deficiency promotes progression and potentiates therapeutic antitumour immunity in hepatitis B virus-related hepatocellular carcinoma by Tao Xing, Li Li, Xiaosong Rao, Jing Zhao, Yiran Chen, Gaoda Ju, Yaping Xu, Xuan Gao, Guilan Dong, Xuefeng Xia, Yanfang Guan, Lingling Zhang, Zhenping Wen, Jun Liang

“…Abstract Background Exploring predictive biomarkers and therapeutic strategies of ICBs has become an urgent need in clinical practice. …”
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Therapeutic Role of Additional Mirror Therapy on the Recovery of Upper Extremity Motor Function after Stroke: A Single-Blind, Randomized Controlled Trial by Xin Wen, Li Li, Xuelian Li, Huanghong Zha, Zicai Liu, Yang Peng, Xuejin Liu, Huiyu Liu, Quan Yang, Jing Wang

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Value of CT‐based radiomics in evaluating the response of bone metastases to systemic drug therapy in breast cancer patients by Miao He, Dongdong Wang, Huijie Li, Meili Sun, Peng Yan, Yongyuan Zhang, Li Li, Dexin Yu, Xiuwen Wang, Yu Hu

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Data supporting the roles of BAP1, STING, and IFN-β in ISGF3 activation in ccRCC by Lauren E. Langbein, Eleonora Sementino, Zhijiu Zhong, Wei Jiang, Li Li, Joseph R. Testa, Haifeng Yang

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Neutrophil-to-lymphocyte ratio for predicting postoperative recurrence in Crohn’s disease patients with isolated anastomotic lesions by Rirong Chen, Chao Li, Kang Chao, Yizhe Tie, Jieqi Zheng, Huili Guo, Zhirong Zeng, Li Li, Minhu Chen, Shenghong Zhang

“…Therapeutic Advances in Gastroenterology…”
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Relationship between bullous pemphigoid and metabolic syndrome: a 12-year case–control study conducted in China by Bingjie Zhang, Xinyi Chen, Yangchun Liu, Fangyuan Chen, Nan Yang, Li Li

“…Therapeutic Advances in Chronic Disease…”
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Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021 by Tingting Jiang, Hui Su, Jing Xu, Chen Li, Ni Zhang, Yanping Li, Yuanlin Wu, Rui Ni, Yue Ming, Ziwei Li, Li Li, Yao Liu

“…Therapeutic Advances in Drug Safety…”
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Opportunities and challenges of pharmacovigilance in special populations: a narrative review of the literature by Yanping Li, Yuanlin Wu, Tingting Jiang, Haiyan Xing, Jing Xu, Chen Li, Rui Ni, Ni Zhang, Guiyuan Xiang, Li Li, Ziwei Li, Lanlan Gan, Yao Liu

“…Therapeutic Advances in Drug Safety…”
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The G285S mutation in nsP1 is sufficient to render Sindbis virus as a stable vector for gene delivery by Xiangwei Shi, Xiangwei Shi, Xiangwei Shi, Xiangwei Shi, Kangyixin Sun, Kangyixin Sun, Kangyixin Sun, You Hu, You Hu, Qinghan Wang, Qinghan Wang, Guoyang Liao, Li Li, Li Li, Pengjie Wen, Pengjie Wen, Leo E. Wong, Fan Jia, Fan Jia, Fan Jia, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu, Fuqiang Xu

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