Transcription Factor OsbZIP60-like Regulating <i>OsP5CS1</i> Gene and 2-Acetyl-1-pyrroline (2-AP) Biosynthesis in Aromatic Rice by Gegen Bao, Umair Ashraf, Lin Li, Jingxuan Qiao, Chunling Wang, Yixiong Zheng

“…In this study, <i>Osp5cs1</i> knockout mutant lines and <i>OsP5CS1</i> over-expression lines were constructed by the genetic transformation of the Indica rice cultivar, i.e., ‘Zhonghua11′, which knocks out <i>OsBADH2</i> to produce fragrance in aromatic rice. …”
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Discussion on Water Condensation in Membrane Pores during CO₂ Absorption at High Temperature by Zhe Phak Chan, Lin Li, Guodong Kang, Norfaizah Ab Manan, Yiming Cao, Tonghua Wang

“…It was found that the liquid accumulation rate in the treated gas knock-out drum was constant during continuous operation for 24 h when all experimental conditions were fixed, indicating a stable degree of membrane wetting. …”
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Consanguineous familial study revealed biallelic FIGLA mutation associated with premature ovarian insufficiency by Beili Chen, Lin Li, Jing Wang, Tengyan Li, Hong Pan, Beihong Liu, Yiran Zhou, Yunxia Cao, Binbin Wang

“…The mutation in the start codon of the FIGLA gene alters the open reading frame, leading to a FIGLA knock-out like phenotype. Conclusions Biallelic mutations in FIGLA may be the cause of POI. …”
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MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression by Vipin Shankar Chelakkot, Kiara Thomas, Todd Romigh, Andrew Fong, Lin Li, Shira Ronen, Shuyang Chen, Pauline Funchain, Ying Ni, Joshua Arbesman

“…Further exploration revealed that breast cancer tissue shows a significantly higher MC1R expression than normal breast tissue, and knocking down MC1R significantly reduced cell proliferation in vitro and in vivo. …”
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Synergistic Interactions between the Hypomethylating Agent Thio-Deoxycytidine and Venetoclax in Myelodysplastic Syndrome Cells by Xiaoyan Hu, Lin Li, Jewel Nkwocha, Kanika Sharma, Liang Zhou, Steven Grant

“…Co-administration of T-dCyd and ABT-199 was associated with the down-regulation of DNA methyltransferase 1 (DNMT1) and synergistic interactions documented by a Median Dose Effect analysis in multiple MDS-derived lines (e.g., MOLM-13, SKM-1, and F-36P). Inducible BCL-2 knock-down significantly increased T-dCyd’s lethality in MOLM-13 cells. …”
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<i>De Novo</i> Purine Nucleotide Biosynthesis Pathway Is Required for Development and Pathogenicity in <i>Magnaporthe oryzae</i> by Meng-Yu Liu, Li-Xiao Sun, Hui Qian, Yun-Ran Zhang, Xue-Ming Zhu, Lin Li, Shuang Liang, Jian-Ping Lu, Fu-Cheng Lin, Xiao-Hong Liu

“…In this study, we focused on the <i>de novo</i> purine biosynthesis (DNPB) pathway and characterized MoAde8, a phosphoribosylglycinamide formyltransferase, catalyzing the third step of the DNPB pathway in <i>M. oryzae</i>. MoAde8 was knocked out, and the mutant (∆<i>Moade8</i>) exhibited purine auxotroph, defects in aerial hyphal growth, conidiation, and pathogenicity, and was more sensitive to hyperosmotic stress and oxidative stress. …”
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Evodiamine inhibits EPRS expression to regulate glutamate metabolism and proliferation of oral squamous cell carcinoma cells by Li‐Qi Lin, Si‐Yi Lv, Hao‐Zhe Ren, Rong‐Rong Li, Lin Li, Yun‐Qing Pang, Jing Wang

“…Glutamate measurements were performed to evaluate the impact of evodiamine on glutamate metabolism of Cal27 and SAS tumor cells. transient transfection techniques were used to knock down and modulate EPRS in these cells. EPRS is expressed at higher levels in OSCC than in normal tissues, and it predicts poor prognosis in patients. …”
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Genetic mapping and functional analysis of a classical tassel branch number mutant Tp2 in maize by Juan Li, Xi Wang, Junfeng Wei, Xinxin Miao, Xiaoyang Shang, Lin Li, Lin Li

“…We conducted a comprehensive study, including phenotypic investigation, genetic mapping, transcriptome analysis, overexpression and CRISPR knock-out, and tsCUT&amp;Tag of Tp2 gene for the molecular dissection of Tp2 mutant. …”
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Carbon Metabolism of a Soilborne Mn(II)-Oxidizing <i>Escherichia coli</i> Isolate Implicated as a Pronounced Modulator of Bacterial Mn Oxidation by Tong Gu, Zhenghu Tong, Xue Zhang, Zhiyong Wang, Zhen Zhang, Tzann-Shun Hwang, Lin Li

“…A total of 16 carbon metabolism-related genes with significant variant expression levels under Mn supplementation conditions were knocked out in the MB266 genome accordingly, but only little effect on the MnODA of each mutant strain was accounted for. …”
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Long non-coding RNA LINC00565 regulates ADAM19 expression through sponging microRNA-532-3p, thereby facilitating clear cell renal cell carcinoma progression by Bin Meng, Pengfei Wang, Chaofei Zhao, Guangwei Yin, Xin Meng, Lin Li, Shengyong Cai, Chengquan Yan

“…Overexpressed ADAM19 could eliminate the anticancer effects caused by knocking down LINC00565 on ccRCC cells. In conclusion, LINC00565 upregulated ADAM19 via absorbing miR-532-3p, thereby facilitating the progression of ccRCC cells.…”
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ABCB5+ mesenchymal stromal cells therapy protects from hypoxia by restoring Ca2+ homeostasis in vitro and in vivo by Kaixuan Yan, Jiaxing Zheng, Mark Andreas Kluth, Lin Li, Christoph Ganss, Benito Yard, Richard Magdeburg, Markus H. Frank, Prama Pallavi, Michael Keese

“…Acute-on-chronic ischemia in Apolipoprotein E knock-out (ApoE−/−) mice was performed by double ligation of the right femoral artery (DFLA). …”
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