Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection by Santhuri Rambaran, Thando Glory Maseko, Lara Lewis, Razia Hassan-Moosa, Derseree Archary, Sinaye Ngcapu, Nigel Garrett, Lyle R. McKinnon, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro

“…Using flow cytometry, we characterized the frequencies and phenotypic differences in monocytes and dendritic cell populations using peripheral blood mononuclear cells from individuals with recurrent, active pulmonary tuberculosis with and without coexisting HIV infection (CAPRISA 011, Clinicaltrials.gov, NCT02114684, 29/01/2014) and compared them to samples from HIV positive individuals and healthy controls. …”
Get full text

Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection by Sunil K. Ahuja, Muthu Saravanan Manoharan, Grace C. Lee, Lyle R. McKinnon, Justin A. Meunier, Maristella Steri, Nathan Harper, Edoardo Fiorillo, Alisha M. Smith, Marcos I. Restrepo, Anne P. Branum, Matthew J. Bottomley, Valeria Orrù, Fabio Jimenez, Andrew Carrillo, Lavanya Pandranki, Caitlyn A. Winter, Lauryn A. Winter, Alvaro A. Gaitan, Alvaro G. Moreira, Elizabeth A. Walter, Guido Silvestri, Christopher L. King, Yong-Tang Zheng, Hong-Yi Zheng, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Keith R. Fowke, Paul N. Harden, Kathryn J. Wood, Martin T. Ferris, Jennifer M. Lund, Mark T. Heise, Nigel Garrett, Kristen R. Canady, Salim S. Abdool Karim, Susan J. Little, Sara Gianella, Davey M. Smith, Scott Letendre, Douglas D. Richman, Francesco Cucca, Hanh Trinh, Sandra Sanchez-Reilly, Joan M. Hecht, Jose A. Cadena Zuluaga, Antonio Anzueto, Jacqueline A. Pugh, South Texas Veterans Health Care System COVID-19 team, Brian K. Agan, Robert Root-Bernstein, Robert A. Clark, Jason F. Okulicz, Weijing He

Get full text

Gardnerella subgroup dominant microbiomes are associated with divergent cervicovaginal immune responses in a longitudinal cohort of Kenyan women by Elinor Shvartsman, Elinor Shvartsman, Elinor Shvartsman, Catia T. Perciani, Meika E. I. Richmond, Meika E. I. Richmond, Justen N. H. Russell, Justen N. H. Russell, Riley H. Tough, Riley H. Tough, Sarah J. Vancuren, Janet E. Hill, KAVI-ICR, Walter Jaoko, Lyle R. McKinnon, Lyle R. McKinnon, Lyle R. McKinnon, Paul A. Sandstrom, Paul A. Sandstrom, Kelly S. MacDonald, Kelly S. MacDonald, Kelly S. MacDonald, Kelly S. MacDonald

Get full text

Baseline host determinants of robust human HIV-1 vaccine-induced immune responses: A meta-analysis of 26 vaccine regimens by Yunda Huang, Yuanyuan Zhang, Kelly E. Seaton, Stephen De Rosa, Jack Heptinstall, Lindsay N. Carpp, April Kaur Randhawa, Lyle R. McKinnon, Paul McLaren, Edna Viegas, Glenda E. Gray, Gavin Churchyard, Susan P. Buchbinder, Srilatha Edupuganti, Linda-Gail Bekker, Michael C. Keefer, Mina C. Hosseinipour, Paul A. Goepfert, Kristen W. Cohen, Brian D. Williamson, M. Juliana McElrath, Georgia D. Tomaras, Juilee Thakar, James J. Kobie

Get full text