The multisensory attentional consequences of tool use: a functional magnetic resonance imaging study by Holmes, N, Spence, C, Hansen, P, Mackay, C, Calvert, G

“…Methodology/Principal Findings: We tested this hypothesis by scanning healthy human participants’ brains using functional magnetic resonance imaging, while they used a simple tool to discriminate between target vibrations, accompanied by congruent or incongruent visual distractors, on the same or opposite side to the tool. …”

Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study. by Norbury, R, Mackay, C, Cowen, P, Goodwin, G, Harmer, C

“…We used functional magnetic resonance imaging to investigate the effects of short-term treatment with reboxetine, a selective noradrenaline reuptake inhibitor, on emotional facial processing in healthy volunteers. …”

The multisensory attentional consequences of tool use: a functional magnetic resonance imaging study. by Holmes, N, Spence, C, Hansen, P, Mackay, C, Calvert, G

“…METHODOLOGY/PRINCIPAL FINDINGS: We tested this hypothesis by scanning healthy human participants' brains using functional magnetic resonance imaging, while they used a simple tool to discriminate between target vibrations, accompanied by congruent or incongruent visual distractors, on the same or opposite side to the tool. …”

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson’s disease by Rolinski, M, Griffanti, L, Piccini, P, Roussakis, A, Szewczyk-Krolikowski1, K, Menke, R, Quinnell, T, Zaiwalla, Z, Klein, J, Mackay, C, Hu, M

“…Resting state functional magnetic resonance imaging dysfunction within the basal ganglia network is a feature of early Parkinson’s disease and may be a diagnostic biomarker of basal ganglia dysfunction. …”

The effects of APOE-ε4 on the BOLD response. by Trachtenberg, A, Filippini, N, Mackay, C

“…In the last decade, functional magnetic resonance imaging (fMRI) has emerged as a tool to study changes in brain function associated with a genetic risk for Alzheimer's disease (AD), with a particular focus on the effects of the APOE-ε4 allele. …”

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease. by Trachtenberg, A, Filippini, N, Cheeseman, J, Duff, E, Neville, M, Ebmeier, K, Karpe, F, Mackay, C

“…Previous functional magnetic resonance imaging (fMRI) studies have shown an effect of APOE genotype on brain function, typically by comparing only ε4 carriers with noncarriers. …”

Increased temporo-insular engagement in unmedicated bipolar II disorder: an exploratory resting state study using independent component analysis. by Yip, S, Mackay, C, Goodwin, G

“…OBJECTIVES: Despite numerous structural and functional magnetic resonance imaging studies, the neurobiology of bipolar disorder (BD) is still incompletely understood. …”

Crossed cerebral lateralization for verbal and visuo-spatial function in a pair of handedness discordant monozygotic twins: MRI and fMRI brain imaging. by Lux, S, Keller, S, Mackay, C, Ebers, G, Marshall, J, Cherkas, L, Rezaie, R, Roberts, N, Fink, G, Gurd, J

“…Imaging of the brain was undertaken using magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI) in combination with manual performance tasks. …”

Bilateral generic working memory circuit requires left-lateralized addition for verbal processing. by Ray, M, Mackay, C, Harmer, C, Crow, T

“…We designed a functional magnetic resonance imaging paradigm to elicit activation in the WM circuit for verbal and spatial information using identical stimuli and applied this in 33 healthy controls. …”

Correspondence of the brain's functional architecture during activation and rest. by Smith, S, Fox, P, Miller, K, Glahn, D, Fox, P, Mackay, C, Filippini, N, Watkins, K, Toro, R, Laird, A, Beckmann, C

“…Independently, we extract the major covarying networks in the resting brain, as imaged with functional magnetic resonance imaging in 36 subjects at rest. The sets of major brain networks, and their decompositions into subnetworks, show close correspondence between the independent analyses of resting and activation brain dynamics. …”

Bilateral generic working memory circuit requires left-lateralized addition for verbal processing by Ray, M, Mackay, C, Harmer, C, Crow, T

“…We designed a functional magnetic resonance imaging paradigm to elicit activation in the WM circuit for verbal and spatial information using identical stimuli and applied this in 33 healthy controls. …”

Donepezil enhances frontal functional connectivity in Alzheimer's Disease: a pilot study by Griffanti, L, Wilcock, G, Voets, N, Bonifacio, G, Mackay, C, Jenkinson, M, Zamboni, G

“…<p>Background: We have previously shown that increased resting-state functional magnetic resonance imaging (fMRI)-based functional connectivity (FC) within the frontal resting-state networks in Alzheimer's disease (AD) patients reflects residual, possibly compensatory, function. …”

Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele. by Suri, S, Mackay, C, Kelly, M, Germuska, M, Tunbridge, E, Frisoni, G, Matthews, P, Ebmeier, K, Bulte, D, Filippini, N

“…BACKGROUND: Functional magnetic resonance imaging (MRI) studies have shown that APOE ε2- and ε4-carriers have similar patterns of blood-oxygenation-level-dependent (BOLD) activation suggesting that we need to look beyond the BOLD signal to link APOE's effect on the brain to Alzheimer's disease (AD)-risk. …”

The effects of reboxetine on emotional processing in healthy volunteers: an fMRI study. by Norbury, R, Mackay, C, Cowen, P, Goodwin, G, Harmer, C

“…The current study, therefore, used functional magnetic resonance imaging (fMRI) to map brain systems activated during successful categorization and subsequent recognition of self-referent positive and negative personality characteristics in healthy volunteers following short-term (7 days) repeated administration of the selective noradrenergic reuptake inhibitor reboxetine. …”

Apolipoprotein E genotype, gender and age modulate connectivity of the hippocampus in healthy adults. by Heise, V, Filippini, N, Trachtenberg, A, Suri, S, Ebmeier, K, Mackay, C

“…Resting-state functional magnetic resonance imaging and diffusion tensor imaging data from 86 cognitively healthy subjects aged 30 to 78years were analysed. …”

Antidepressant drug treatment modifies the neural processing of nonconscious threat cues. by Harmer, C, Mackay, C, Reid, C, Cowen, P, Goodwin, G

“…METHODS: The current study assessed the effects of 7 days administration of the selective serotonin reuptake inhibitor (SSRI), citalopram, on amygdala responses to masked presentations of fearful and happy facial expressions in never-depressed volunteers using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging. A double-blind, between-groups design was used with volunteers randomized to 20 mg/day citalopram versus placebo. …”

Antidepressant drug treatment modifies the neural processing of nonconscious threat cues by Harmer, C, Mackay, C, Reid, C, Cowen, P, Goodwin, G

“…<strong>Methods</strong>: The current study assessed the effects of 7 days administration of the selective serotonin reuptake inhibitor (SSRI), citalopram, on amygdala responses to masked presentations of fearful and happy facial expressions in never-depressed volunteers using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging. A double-blind, between-groups design was used with volunteers randomized to 20 mg/day citalopram versus placebo. …”

Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. by Rogers, R, Ramnani, N, Mackay, C, Wilson, J, Jezzard, P, Carter, C, Smith, S

“…METHODS: Fourteen healthy volunteers completed an event-based functional magnetic resonance imaging protocol to investigate blood-oxygenation-level-dependent (BOLD) responses during independently modeled phases of choice cognition. …”

The neural basis of flashback formation: the impact of viewing trauma. by Bourne, C, Mackay, C, Holmes, E

“…Method A total of 22 healthy volunteers viewed a traumatic film whilst undergoing functional magnetic resonance imaging (fMRI). They kept a 1-week diary to record flashbacks to specific film scenes. …”

The neural basis of flashback formation: The impact of viewing trauma by Bourne, C, Mackay, C, Holmes, E

“…Method A total of 22 healthy volunteers viewed a traumatic film whilst undergoing functional magnetic resonance imaging (fMRI). They kept a 1-week diary to record flashbacks to specific film scenes. …”