Epigenetic Regulation of Gfi1 in Endocrine-Related Cancers: A Role Regulating Tumor Growth by Nadia Ashour, Javier C. Angulo, Ana González-Corpas, María J. Orea, María V. T. Lobo, Ramón Colomer, Begoña Colás, Manel Esteller, Santiago Ropero

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Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells by Rosa Hernández, Cristina Jiménez-Luna, Raúl Ortiz, Fernando Setién, Miguel López, Gloria Perazzoli, Manel Esteller, María Berdasco, Jose Prados, Consolación Melguizo

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P822: EPIGENETIC REGULATION OF CD155 ON MULTIPLE MYELOMA CELLS INFLUENCES ANTI-TUMOR NOVEL IMMUNOTHERAPEUTIC APPROACHES by Laura Martinez-Verbo, Lorea Villanueva, Pere Llinàs-Arias, Carlos Antonio García-Prieto, David Piñeyro, Aina Oliver-Caldes, Almudena García-Ortiz, Antonio Valeri, Carlos Fernández De Larrea, Joaquin Martínez-López, Gerardo Ferrer, Manel Esteller

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PB1705: THE HISTONE MODIFIER SETD6 IS EPIGENETICALLY REGULATED IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND INTERFERES WITH PROLIFERATION AND GENE EXPRESSION by Yoana Veselinova, Ignacio Campillo-Marcos, Margalida Rossello-Tortella, Fernando Setien, Gerardo Ferrer, Manel Esteller

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Bromodomain inhibitors and cancer therapy: From structures to applications by Montserrat Pérez-Salvia, Manel Esteller

“…Moreover, proteins containing bromodomains are also epigenetic regulators, although little is known about the specific function of these domains. …”
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Modulation of Colorectal Tumor Behavior via lncRNA TP53TG1-Lipidic Nanosystem by Farimah Masoumi, Sofia M. Saraiva, Belén L. Bouzo, Rafael López-López, Manel Esteller, Ángel Díaz-Lagares, María de la Fuente

“…In gastrointestinal cancers, TP53 target 1 (TP53TG1) is an epigenetically regulated lncRNA that represents a promising therapeutic target due to its tumor suppressor properties regulating the p53-mediated DNA damage and the intracellular localization of the oncogenic YBX1 protein. …”
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Follow-Up Study Confirms the Presence of Gastric Cancer DNA Methylation Hallmarks in High-Risk Precursor Lesions by Antonio Gómez, Miguel L. Pato, Luis Bujanda, Núria Sala, Osmel Companioni, Ángel Cosme, Martina Tufano, David J. Hanly, Nadia García, José Miguel Sanz-Anquela, Javier P. Gisbert, Consuelo López, José Ignacio Elizalde, Miriam Cuatrecasas, Victoria Andreu, María José Paules, María Dolores Martín-Arranz, Luis Ortega, Elvira Poves, Jesús Barrio, María Ángeles Torres, Guillermo Muñoz, Ángel Ferrández, María José Ramírez-Lázaro, Sergio Lario, Carlos A González, Manel Esteller, María Berdasco

“…As a result, we ascertained that intestinal metaplasia partially recapitulates patterns of aberrant methylation of intestinal type of gastric cancer, independently of the <i>H. pylori</i> status. Two epigenetically regulated genes in cancer, <i>RPRM</i> and <i>ZNF793</i>, consistently showed increased methylation in intestinal metaplasia with respect to earlier precursor lesions. …”
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