Effects of ramipril on endothelial function and the expression of proinflammatory cytokines and adhesion molecules in young normotensive subjects with successfully repaired coarcta... by Brili, S, Tousoulis, D, Antoniades, C, Vasiliadou, C, Karali, M, Papageorgiou, N, Ioakeimidis, N, Marinou, K, Stefanadi, E, Stefanadis, C

“…Endothelial function was evaluated in the right forearm by gauge-strain plethysmography, and serum levels of interleukin (IL)-1b, IL-6, soluble CD40 ligand (sCD40L), and soluble vascular cell adhesion molecule (sVCAM)-1 were determined by enzyme-linked immunosorbent assay. …”

Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation. by Stefanadi, E, Tousoulis, D, Antoniades, C, Katsi, V, Bosinakou, E, Vavuranakis, E, Triantafyllou, G, Marinou, K, Tsioufis, C, Papageorgiou, N, Latsios, G, Stefanadis, C

“…We investigated the effect of low-dose atorvastatin treatment on the kinetics of cytokine IL-6, vascular cell adhesion molecule (sVCAM-1) and endothelium-derived markers of thrombosis/fibrinolysis such as von Willebrand factor (vWF), plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA), post STEMI. …”

Selective serotonin reuptake inhibitors modify the effect of beta-blockers on long-term survival of patients with end-stage heart failure and major depression. by Tousoulis, D, Antoniades, C, Drolias, A, Stefanadi, E, Marinou, K, Vasiliadou, C, Tsioufis, C, Toutouzas, K, Latsios, G, Stefanadis, C

“…At baseline, patients with severe MD had higher serum interleukin 6 (P < .05) and soluble vascular cell adhesion molecule (P < .01). During the follow-up, 167 cardiovascular deaths were reported, and MD was 1 of the major predictors of cardiovascular death (P = .031), whereas treatment with angiotensin receptor inhibitors and statins were also important negative predictors of mortality (P = .036 and P = .039, respectively). …”

Effects of insulin dependence on inflammatory process, thrombotic mechanisms and endothelial function, in patients with type 2 diabetes mellitus and coronary atherosclerosis. by Antoniades, C, Tousoulis, D, Marinou, K, Papageorgiou, N, Bosinakou, E, Tsioufis, C, Stefanadi, E, Latsios, G, Tentolouris, C, Siasos, G, Stefanadis, C

“…Patients in INS group had higher levels of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), monocyte chemoattractant protein (MCP-1) and vascular cell adhesion molecule (sVCAM-1), compared to TABL. However, TNF-alpha was negatively correlated with protein C (PrtC) only in INS (r = - 0.726, p = 0.01) but not in TABL group (r = - 0.066, p = 0.738). …”

Differences in inflammatory and thrombotic markers between unstable angina and acute myocardial infarction. by Tousoulis, D, Antoniades, C, Bosinakou, E, Kotsopoulou, M, Tsoufis, C, Marinou, K, Charakida, M, Stefanadi, E, Vavuranakis, M, Latsios, G, Stefanadis, C

“…RESULTS: Patients with UA had significantly higher levels of interleukin-6 (IL-6), soluble vascular cells adhesion molecule (sVCAM-1) and von Willebrand factor (vWF) (p<0.05 vs controls), and lower levels of antithrombin III (ATIII) (p<0.01 vs controls) and protein C (PrtC) (p<0.05 vs controls). …”

Methionine-loading rapidly impairs endothelial function, by mechanisms independent of endothelin-1: evidence for an association of fasting total homocysteine with plasma endothelin... by Tousoulis, D, Antoniades, C, Marinou, K, Vasiliadou, C, Bouras, G, Stefanadi, E, Latsios, G, Siasos, G, Toutouzas, K, Stefanadis, C

“…Forearm vasodilatory response to reactive hyperemia, plasma total homocysteine (tHcy), oxidized LDL (ox-LDL), ET-1 and soluble vascular cell adhesion molecule (sVCAM-1), were evaluated at baseline and 4 hours post methionine loading (4hPML). …”

Interaction between cytokines and sCD40L in patients with stable and unstable coronary syndromes. by Tousoulis, D, Antoniades, C, Nikolopoulou, A, Koniari, K, Vasiliadou, C, Marinou, K, Koumallos, N, Papageorgiou, N, Stefanadi, E, Siasos, G, Stefanadis, C

“…Circulating levels of sCD40L, interleukin-6 (IL-6), soluble vascular cell adhesion molecule-a (sVCAM-1) and soluble intercellular adhesion molecule-1 (sICAM-1) were determined by enzyme-linked immunosorbent assay (ELISA). …”

Genetic polymorphism on type 2 receptor of angiotensin II, modifies cardiovascular risk and systemic inflammation in hypertensive males. by Tousoulis, D, Koumallos, N, Antoniades, C, Antonopoulos, A, Bakogiannis, C, Milliou, A, Marinou, K, Kallikazarou, E, Stefanadi, E, Mentzikof, D, Stefanadis, C

“…Serum levels of C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6) and soluble vascular cell adhesion molecule-1 (sVCAM-1) were measured in all the participants. …”