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A DPP-mediated feed-forward loop canalizes morphogenesis during Drosophila dorsal closure
Published 2015“…We propose that the main function of DPP pathway during Drosophila DC is to ensure robust morphogenesis, a distinct function from its well-established ability to spread spatial information.…”
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Stochastic Turing patterns in a synthetic bacterial population
Published 2019“…These findings provide the groundwork for a unified picture of biological morphogenesis, arising from a combination of stochastic gene expression and dynamical instabilities. …”
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Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks
Published 2016“…The actin cytoskeleton—a complex, nonequilibrium network consisting of filaments, actin-crosslinking proteins (ACPs) and motors—confers cell structure and functionality, from migration to morphogenesis. While the core components are recognized, much less is understood about the behaviour of the integrated, disordered and internally active system with interdependent mechano-chemical component properties. …”
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Growth factor regulation of proliferation and survival of multipotential stromal cells
Published 2012“…Growth factors are known to influence cell proliferation, motility, survival and morphogenesis. In the case of MSCs, it would be beneficial that the growth factor does not induce differentiation at an early stage since the number of early-differentiating progenitors would be very low. …”
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The contractile ring coordinates curvature-dependent septum assembly during fission yeast cytokinesis
Published 2015“…Mechanical regulation of the cell wall assembly may have general relevance to the morphogenesis of walled cells.…”
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Numerous recursive sites contribute to accuracy of splicing in long introns in flies
Published 2018“…Recursive sites occur in most very long (> 40 kb) fly introns, including many genes involved in morphogenesis and development, and tend to occur near the midpoints of introns. …”
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Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels
Published 2014“…These heterotypic cell type assays can be used to study cell survival, proliferation, migration, morphogenesis and differentiation under controlled conditions. …”
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Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells
Published 2014“…Although cortical actin plays an important role in cellular mechanics and morphogenesis, there is surprisingly little information on cortex organization at the apical surface of cells. …”
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Mechanism of a flow-gated angiogenesis switch: early signaling events at cell–matrix and cell–cell junctions
Published 2014“…Application of B–A, but not A–B flow, to cultured endothelial monolayers was found to promote capillary morphogenesis and resulted in distinct localization patterns of VE-cadherin and increased FAK phosphorylation. …”
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Signaling network state predicts Twist-mediated effects on breast cell migration across diverse growth factor contexts
Published 2012“…Epithelial-mesenchymal transition (EMT), whether in developmental morphogenesis or malignant transformation, prominently involves modified cell motility behavior. …”
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