Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation by Jarosz, Daniel F., Lindquist, Susan

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Distinct Prion Strains Are Defined by Amyloid Core Structure and Chaperone Binding Site Dynamics by Frederick, Kendra K., Debelouchina, Galia Tzvetanova, Kayatekin, Can, Dorminy, Tea, Jacavone, Angela, Griffin, Robert Guy, Lindquist, Susan

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Creating an Interdisciplinary Introductory Chemistry Course without Time-Intensive Curriculum Changes by Taylor, Elizabeth Vogel, Mitchell, Rudolph, Drennan, Catherine L.

“…Accordingly, new recommendations for premedical curricula issued by the American Association of Medical Colleges (AAMC) and the Howard Hughes Medical Institute (HHMI) call for a competency-based training, shifting away from specific course requirements to the ability of students to apply knowledge and recognize underlying scientific principles in medicine (3). …”
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Prions are a common mechanism for phenotypic inheritance in wild yeasts by Halfmann, Randal Arthur, Jarosz, Daniel F., Jones, Sandra K., Chang, Amelia, Lancaster, Alex K., Lindquist, Susan

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Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation by Amor, Alvaro J., Schmitz, Karl R., Baker, Tania A., Sauer, Robert T.

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An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes by Goldman, Peter J., Hamill, Michael J., Howard-Jones, Annaleise R., Walsh, Christopher T., Elliott, Sean J., Drennan, Catherine L., Ryan, Katherine S., Ryan, Katherine S.

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Clofarabine Targets the Large Subunit (α) of Human Ribonucleotide Reductase in Live Cells by Assembly into Persistent Hexamers by Aye, Yimon, Long, Marcus J.C., Chittuluru, Johnathan, Asturias, Francisco J., Stubbe, JoAnne, Brignole, Edward J, Drennan, Catherine L

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N domain of the Lon AAA+ protease controls assembly and substrate choice by Brown, Breann L., Vieux, Ellen F., Kalastavadi, Tejas, Kim, SaRa, Chen, James Z., Baker, Tania A.

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Splice isoform and pharmacological studies reveal that sterol depletion relocalizes  -synuclein and enhances its toxicity by Termine, Daniel J., Lindquist, Susan, Valastyan, Julie Suzanne

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Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin by LeRoux, Michele, Culviner, Peter H, Liu, Yue J, Littlehale, Megan L, Laub, Michael T

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Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses by Bronson, Roderick T., Joshi, Nikhil, Akama-Garren, Elliot H., Lu, Yisi, Lee, Da-Yae, Chang, Gregory, Li, Amy, DuPage, Michel J., Tammela, Tuomas, Kerper, Natanya R., Farago, Anna F., Robbins, Rebecca, Crowley, Denise G., Jacks, Tyler E.

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Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver by Naba, Alexandra, Clauser, Karl R., Whittaker, Charles A., Carr, Steven A., Tanabe, Kenneth K., Hynes, Richard O

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Dorcas Cummings lecture by Page, David C

“…Page is a Professor of Biology at the Massachusetts Institute of Technology, an Investigator of the Howard Hughes Medical Institute, and the Director of the Whitehead Institute for Biomedical Research.…”
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A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary by Junker, Jan Philipp, Gill, Mark E., Mueller, Jacob L., van Oudenaarden, Alexander, Soh, Ying Qi Shirleen, Page, David C

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A Central Role for mTOR in Lipid Homeostasis by Lamming, Dudley W., Sabatini, David M., Lamming, Dudley W., Sabatini, David

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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment by Acharya, Nandini, Madi, Asaf, Zhang, Huiyuan, Klapholz, Max, Escobar, Giulia, Dulberg, Shai, Christian, Elena, Ferreira, Michelle, Dixon, Karen O, Fell, Geoffrey, Tooley, Katherine, Mangani, Davide, Xia, Junrong, Singer, Meromit, Bosenberg, Marcus, Neuberg, Donna, Rozenblatt-Rosen, Orit, Regev, Aviv, Kuchroo, Vijay K, Anderson, Ana C

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An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets by Zhang, Huiyuan, Madi, Asaf, Yosef, Nir, Chihara, Norio, Awasthi, Amit, Pot, Caroline, Lambden, Conner, Srivastava, Amitabh, Burkett, Patrick R, Nyman, Jackson, Christian, Elena, Etminan, Yasaman, Lee, Annika, Stroh, Helene, Xia, Junrong, Karwacz, Katarzyna, Thakore, Pratiksha I, Acharya, Nandini, Schnell, Alexandra, Wang, Chao, Apetoh, Lionel, Rozenblatt-Rosen, Orit, Anderson, Ana C, Regev, Aviv, Kuchroo, Vijay K

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mTOR at the nexus of nutrition, growth, ageing and disease by Liu, Grace Y, Sabatini, David M

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Modelling Neurodegeneration in Saccharomyces Cerevisiae: Why Cook with Baker's Yeast? by Khurana, Vikram, Lindquist, Susan

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The evolution of metazoan extracellular matrix by Hynes, Richard O

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