Report on the National Eye Institute Audacious Goals Initiative: Regenerating the Optic Nerve by Goldberg, Jeffrey L., Guido, William, Constantine-Paton, Martha, AGI Workshop Participants

“…The National Eye Institute (NEI) hosted a workshop on November 19, 2014, as part of the Audacious Goals Initiative (AGI), an NEI-led effort to rapidly expand therapies for eye diseases through coordinated research funding. …”
Get full text
Get full text

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing by Church, George M, Hynes, Richard O, Kiani, Samira, Liu, David R., Lunshof, Jeantine E., Zhang, Feng

“…In this perspective, some three dozen experts from the fields of genome editing, medicine, bioethics, law, and related fields offer their candid reactions to the National Academies/Royal Society report, highlighting areas of support, omissions, disagreements, and priorities moving forward.…”
Get full text

Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains by Littleton, J. Troy, Melom, Jan Elizabeth, Jorquera, Ramon, Barber, Cynthia F.

Subjects: “…United States National Institutes of Healt (Grant NS40296)…”
Get full text
Get full text

A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease by PrabhuDas, Mercy R., Baldwin, Cynthia L., Bollyky, Paul L., Bowdish, Dawn M. E., Drickamer, Kurt, Febbraio, Maria, Herz, Joachim, Kobzik, Lester, Krieger, Monty, Loike, John, McVicker, Benita, Means, Terry K., Moestrup, Soren K., Post, Steven R., Sawamura, Tatsuya, Silverstein, Samuel, Speth, Robert C., Telfer, Janice C., Thiele, Geoffrey M., Wang, Xiang-Yang, Wright, Samuel D., El Khoury, Joseph

“…To address this problem, a workshop was organized by theUnited StatesNational Institute of Allergy and Infectious Diseases, National Institutes of Health, to help develop a clear definition of scavenger receptors and a standardized nomenclature based on that definition. …”
Get full text
Get full text

Plant Solutions for the COVID-19 Pandemic and Beyond: Historical Reflections and Future Perspectives by Weng, Jing-Ke

“…National Science Foundation (Grant CHE-1709616)…”
Get full text

Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S-cerevisiae by Erlich, Rachel L., Fry, Rebecca C., Begley, Thomas J., Daee, Danielle L., Lahue, Robert S., Samson, Leona D.

“…National Institute of Health (grants CA055042, ES002109 and CA14051)…”
Get full text
Get full text

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure by Wang, Xinchen, Kellis, Manolis, Boyer, Laurie Ann

Get full text
Get full text

Integrated genomic analyses of ovarian carcinoma by Meyerson, Matthew L., Lander, Eric Steven

Get full text

Comprehensive genomic characterization of squamous cell lung cancers by Park, Peter J., Lander, Eric Steven

Get full text

Comprehensive molecular characterization of human colon and rectal cancer by Lander, Eric Steven

Get full text

Integrated genomic characterization of endometrial carcinoma by Park, Peter J., Lander, Eric Steven

Get full text

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas by Ma, Haiting, Wert, Katherine J., Shvartsman, Dmitry, Melton, Douglas A., Jaenisch, Rudolf

Get full text

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood by Khera, Amit V., Chaffin, Mark, Wade, Kaitlin H., Zahid, Sohail, Brancale, Joseph, Xia, Rui, Distefano, Marina, Senol-Cosar, Ozlem, Haas, Mary E., Bick, Alexander, Aragam, Krishna G., Lander, Eric Steven, Smith, George Davey, Mason-Suares, Heather, Fornage, Myriam, Lebo, Matthew, Timpson, Nicholas J., Kaplan, Lee M., Kathiresan, Sekar

Get full text

Distinct quaternary structures of the AAA+ Lon protease control substrate degradation by Vieux (Kloss), Ellen, Wohlever, Matthew Lee, Chen, James Z., Baker, Tania, Sauer, Robert T

Get full text
Get full text

An endogenous dAMP ligand in by Maggiolo, Ailiena O., Thomas, William C., Meisburger, Steve P., Boal, Amie K., Parker, Mackenzie James, Kim, Albert Dong Woo, Ando, Nozomi, Stubbe, JoAnne

“…© 2018 National Academy of Sciences. All rights reserved. …”
Get full text
Get full text
Get full text

Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects by Medeiros, Lea Ann, Dennis, Lucas M., Gill, Mark E., Houbaviy, Hristo, Markoulaki, Styliani, Fu, Dongdong, White, Amy C., Kirak, Oktay, Sharp, Phillip A., Jaenisch, Rudolf, Page, David C

Get full text
Get full text
Get full text

Epigenetic memory in induced pluripotent stem cells by Kim, K., Doi, A., Wen, B., Ng, K., Zhao, R., Cahan, Patrick, Kim, J., Aryee, M. J., Ji, H., Ehrlich, L. I. R., Yabuuchi, A., Takeuchi, A., Cunniff, K. C., Hongguang, H., Mckinney-Freeman, S., Naveiras, O., Yoon, T. J., Irizarry, Rafael A., Jung, N., Seita, J., Hanna, Jacob, Murakami, P., Jaenisch, Rudolf, Weissleder, R., Orkin, Stuart H.

Get full text

Identification of a Paralog-Specific Notch1 Intracellular Domain Degron by Broadus, Matthew R., Chen, Tony W., Neitzel, Leif R., Ng, Victoria H., Jodoin, Jeanne, Lee, Laura A., Salic, Adrian, Robbins, David J., Capobianco, Anthony J., Patton, James G., Huppert, Stacey S., Lee, Ethan

Get full text
Get full text

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness by Chen, Walter W., Marjanovic, Nemanja, Zoncu, Roberto, Katajisto, Pekka, Dohla, Julia, Chaffer, Christine L., Pentinmikko, Nalle, Iqbal, Sharif, Weinberg, Robert A, Sabatini, David

Get full text
Get full text
Get full text
Get full text

Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain by Svoboda, Devon S., Barrasa, M. Inmaculada, Shu, Jian, Rietjens, Rosalie, Zhang, Shupei, Mitalipova, Maya, Berube, Peter, Fu, Dongdong, Shultz, Leonard D., Bell, George W., Jaenisch, Rudolf

Get full text