Characterization of metabolite profile in Phyllanthus niruri and correlation with bioactivity elucidated by nuclear magnetic resonance based metabolomics by Mediani, Ahmed, Abas, Faridah, Maulidiani, M., Khatib, Alfi, Tan, Chin Ping, Ismail, Intan Safinar, Shaari, Khozirah, Ismail, Amin

“…Herein, three dried P. niruri samples, air (AD), freeze (FD) and oven (OD), extracted with various ethanol to water ratios (0%, 50%, 70%, 80% and 100%) were evaluated for their metabolite changes using proton nuclear magnetic resonance (1H-NMR)-based metabolomics approach. …”
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Characterization of metabolite profile in Phyllanthus niruri and correlation with bioactivity elucidated by nuclear magnetic resonance based metabolomics by Mediani, Ahmed, Abas, Faridah, Maulidiani, M., Khatib, Alfi, Chin, Ping Tan, Ismail, Intan Safinar, Shaari, Khozirah, Ismail, Amin

“…Herein, three dried P. niruri samples, air (AD), freeze (FD) and oven (OD), extracted with various ethanol to water ratios (0%, 50%, 70%, 80% and 100%) were evaluated for their metabolite changes using proton nuclear magnetic resonance (¹H-NMR)-based metabolomics approach. …”
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Metabolite profiling, antioxidant, and a-glucosidase inhibitory activities of germinated rice: nuclear-magnetic-resonance-based metabolomics study by Pramai, Phaiwan, Abdul Hamid, Nur Ashikin, Mediani, Ahmed, Maulidiani, Maulidiani, Abas, Faridah, Jiamyangyuen, Sudarat

“…In an attempt to profile the metabolites of three different varieties of germinated rice, specifically black (GBR), red, and white rice, a 1H-nuclear-magnetic-resonance-based metabolomics approach was conducted. …”
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NMR-based metabolomics for quality control of Dukung Anak (Phyllanthus niruri Linn.) and identification of biomarkers for its diabetes-related activities by Mediani, Ahmed

Subjects: “…Nuclear magnetic resonance…”
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Complementary NMR- and MS-based metabolomics approaches reveal the correlations of phytochemicals and biological activities in Phyllanthus acidus leaf extracts by Abd Ghafar, Siti Zulaikha, Mediani, Ahmed, M., Maulidiani, R., Rudiyanto, Mohd Ghazali, Hasanah, Ramli, Nurul Shazini, Abas, Faridah

“…Proton nuclear magnetic resonance (1H NMR)- and ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)-based analytical tools are frequently used in metabolomics studies. …”
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Identification of α-glucosidase inhibitory compounds from Curcuma mangga fractions by Awin, Tahani M., Mediani, Ahmed, Mohd Faudzi, Siti Munirah, Maulidiani, M., Sze, Wei Leong, Shaari, Khozirah, Abas, Faridah

“…The extraction solvents used have a strong effect on the metabolite profile and the bioactivity of the extract. A nuclear magnetic resonance (NMR)-based metabolomics approach was used to differentiate the metabolite profiles of hexane, chloroform, ethyl acetate, and methanol fractions of C. mangga rhizomes and to correlate the metabolites with α-glucosidase inhibitory activity. …”
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1H-NMR-based metabolomics approach to understanding the drying effects on the phytochemicals in Cosmos caudatus by Mediani, Ahmed, Abas, Faridah, Khatib, Alfi, Maulidiani, H, Shaari, Khozirah, Choi, Young Hae, Lajis, Nordin

“…medicinal herb to treat several maladies. Proton nuclear magnetic resonance (1H-NMR) combined with principal component analysis (PCA) and partial least-squares analysis (PLS) was applied to distinguish variations among C. caudatus materials processed with various drying techniques. …”
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Physicochemical characteristics, nutritional composition, and phytochemical profiles of nine Algerian date palm fruit (Phoenix dactylifera L.) varieties by Abdul Hamid, Nur Ashikin, Maulidiani, Maulidiani, Mediani, Ahmed, Yahya, Ummul Izzatul Izzah, Ismail, Intan Safinar, Tham, Chau Ling, Shadid, Khalid, Abas, Faridah

“…Nine varieties of Algerian date palm fruits (Phoenix dactylifera L.) including Lahmira, Timjouhert, Adham Talmine, Deglet Talmine, Adam Boullah, Tinasser, Deglet, Deglet Nour, and Takerbouch were distinguished via Proton Nuclear Magnetic Resonance (1H‐NMR) metabolomics approach. The quality was evaluated based on the metabolite composition, proximate analysis, physicochemical characteristics, and biological activities which include nitric oxide (NO) inhibition via the cell‐based approach and NO scavenging abilities. …”
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Identification of nitric oxide inhibitory compounds from the rhizome of Curcuma xanthorrhiza by Awin, Tahani M., Buzgaia, Nawal, Abd Ghafar, Siti Zulaikha, Mediani, Ahmed, Mohd Zaudzi, Siti Munirah, Maulidiani, M., Shaari, Khozirah, Abas, Faridah

“…This study profiles the metabolites in different fractions (hexane, chloroform, ethyl acetate and methanol) of the ethanolic extracts of C. xanthorrhiza using a nuclear magnetic resonance-based metabolomics approach. The nitric oxide (NO) inhibitory activity was determined using a Griess assay. …”
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Phytochemical and bioactivity alterations of Curcuma species harvested at different growth stages by NMR-based metabolomics by Awin, Tahani M., Mediani, Ahmed, Maulidiani, Leong, Sze Wei, Mohd Faudzi, Siti Munirah, Shaari, Khozirah, Abas, Faridah

“…This study aims to profile the metabolites in four Curcuma species, including C. zedoaria, C. xanthorrhiza, C. aeruginosa and C. mangga at three developmental stages (seven, eight and nine months old) using nuclear magnetic resonance (NMR)-based metabolomics. Principal component analysis (PCA) showed that there are metabolites changes due to the month of harvest in each of the four species. …”
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Quality evaluation of the physical properties, phytochemicals, biological activities and proximate analysis of nine Saudi date palm fruit varieties by Abdul-Hamid, Nur Ashikin, Mustaffer, Nur Hafizah, Maulidiani, M., Mediani, Ahmed, Ismail, Intan Safinar, Chau, Ling Tham, Abas, Faridah

“…Nine date palm varieties Berni, Halaoua, Shalabi, Sogaai, Sukkari, Nebtat Ali, Anbara, Ajwa and Medjoul were evaluated via the Proton Nuclear Magnetic Resonance (1H NMR) based metabolomics approach. …”

1 H NMR-based metabolomics approach in investigating the chemical profile, antioxidant and anti-inflammatory activities of Gynura procumbens and Cleome gynandra by Chandradevan, Machap, Simoh, Sanimah, Mediani, Ahmed, Ismail, Intan Safinar, Abas, Faridah

“…The present study aims to evaluate the relationship between the chemical compositions of both herbs and their antioxidant and anti-inflammatory properties using nuclear magnetic resonance (NMR) metabolomics approach, which is being reported for the first time. …”
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Phytochemical and biological features of Phyllanthus niruri and Phyllanthus urinaria harvested at different growth stages revealed by 1H NMR-based metabolomics by Abas, Faridah, Ismail, Intan Safinar, Ismail, Amin, Shaari, Khozirah, Lajis, Md. Nordin, Tan, Chin Ping, Khatib, Alfi, Mediani, Ahmed

“…The variation between two Phyllanthus species (P. niruri and P. urinaria) was studied using proton nuclear magnetic resonance (1H NMR) combined with multivariate data analysis (MVDA). …”
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Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics by Leng, Wei Khoo, Mediani, Ahmed, Zolkeflee, Nur Khaleeda Zulaikha, Sze, Wei Leong, Ismail, Intan Safinar, Khatib, Alfi, Shaari, Khozirah, Abas, Faridah

“…In order to maximize retention of the original chemical profile of the herb and quality assurance, optimization of processing methods is needed. Using nuclear magnetic resonance (NMR) based metabolomics approach, we have carried out a discriminative analysis of the metabolite profiles of the leaves and stems of the herb when different drying (air, oven, and freeze) and extraction (soaking and sonication) methods were used and correlated the metabolite profiles with the total phenolic content (TPC), antioxidant and α-glucosidase inhibitory activities. …”
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Metabolite characterization of different palm date varieties and the correlation with their NO inhibitory activity, texture and sweetness by Abdul Hamid, Nur Ashikin, Mediani, Ahmed, Maulidiani, M., Shadid, Khalid, Ismail, Intan Safinar, Abas, Faridah, Lajis, Nordin H.

“…The differences of metabolome were inves-tigated using proton nuclear magnetic resonance (1HNMR) spectroscopy combined with multivariate data analysis (MVDA). …”
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Metabolomic analysis and biochemical changes in the urine and serum of streptozotocin-induced normal- and obese-diabetic rats by Mediani, Ahmed, Abas, Faridah, M., Maulidiani, Abu Bakar Sajak, Azliana, Khatib, Alfi, Chin, Ping Tan, Ismail, Intan Safinar, Shaari, Khozirah, Ismail, Amin, N. H., Lajis

“…This was done byevaluating their urine metabolites using proton nuclear magnetic resonance (1H NMR)-based metabolomics and comparing withcontrols at different time points, considering the induction periods of obesity and diabetes. …”
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Metabolites and biological activities of Phoenix dactylifera L. pulp and seeds: a comparative MS and NMR based metabolomics approach by Abdul Hamid, Nur Ashikin, Abas, Faridah, Ismail, Intan Safinar, Chau, Ling Tham, Maulidiani, M., Mediani, Ahmed, Swarup, Sanjay, Umashankar, Shivshankar, Zolkeflee, Nur Khaleeda Zulaikha

“…This study aims to evaluate the metabolite profiles of date pulp and seeds utilizing 1H nuclear magnetic resonance (NMR) and ultra-high performance liquid chromatography mass spectrometry (UHPLC-MS) techniques. …”
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Phytochemical profiles and biological activities of Curcuma species subjected to different drying methods and solvent systems: NMR-based metabolomics approach by Awin, Tahani, Mediani, Ahmed, Maulidiani, Shaari, Khozirah, Mohd Faudzi, Siti Munirah, Sukari, Mohd Aspollah, Lajis, Nordin, Abas, Faridah

“…Their phytochemical constituents were also determined by a proton nuclear magnetic resonance (1H NMR) based metabolomics approach. …”
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Metabolomic and antioxidant properties of different varieties and origins of dragon fruit by Al-Mekhlafi, Nabil Ali, Mediani, Ahmed, Ismail, Nor Hadiani, Abas, Faridah, Dymerski, Tomasz, Lubinska-Szczygeł, Martyna, Vearasilp, Suchada, Gorinstein, Shela

“…This study was aimed to evaluate the differences among dragon fruit varieties extracted with methanol–water (CD3OD-D2O) and methanol (CD3OD) by proton nuclear magnetic resonance (1H NMR)-based metabolomics approach. …”

Application of BATMAN and BAYESIL for quantitative ¹H-NMR based metabolomics of urine: discriminant analysis of lean, obese, and obese-diabetic rats by Maulidiani, Rudiyanto, Mediani, Ahmed, Khatib, Alfi, Ismail, Amin, Hamid, Muhajir, H. Lajis, Nordin, Shaari, Khozirah, Abas, Faridah

“…Introduction: BATMAN and BAYESIL are software tools, which can provide a solution for automated metabolite quantifications based on the proton nuclear magnetic resonance (1H-NMR) spectral data of bio-fluids. …”
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