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Variability of Botulinum Toxins: Challenges and Opportunities for the Future
Published 2018-09-01Get full text
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Antibodies and Vaccines against Botulinum Toxins: Available Measures and Novel Approaches
Published 2019-09-01Get full text
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Recent Developments in Botulinum Neurotoxins Detection
Published 2022-05-01“…Therefore, fast, precise, and more reliable detection methods are still required to monitor outbreaks and ensure surveillance of botulism. The botulinum toxin field also comprises therapeutic uses, basic research studies and biodefense issues. …”
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4
Regulatory Networks Controlling Neurotoxin Synthesis in <i>Clostridium botulinum</i> and <i>Clostridium tetani</i>
Published 2022-05-01“…<i>Clostridium botulinum</i> and <i>Clostridium tetani</i> are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively. …”
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Bacterial Toxins, Current Perspectives
Published 2020-09-01“…Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease. For example, botulinum toxins (BoNTs) and tetanus toxin (TeNT) are the unique causal factors of botulism and tetanus, respectively. …”
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Engineering Botulinum Neurotoxins for Enhanced Therapeutic Applications and Vaccine Development
Published 2020-12-01“…This review summarizes current knowledge related to engineering of botulinum toxins, with particular emphasis on their potential therapeutic applications for pain management and for retargeting to non-neuronal tissues. …”
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