Physical Activity Prevents Cartilage Degradation: A Metabolomics Study Pinpoints the Involvement of Vitamin B6 by Michela Deiana, Giovanni Malerba, Luca Dalle Carbonare, Samuele Cheri, Cristina Patuzzo, Grygoriy Tsenov, Lucas Moron Dalla Tor, Antonio Mori, Gianantonio Saviola, Donato Zipeto, Federico Schena, Monica Mottes, Maria Teresa Valenti

“…To evaluate PA effects on the chondrocyte lineage, we analyzed the expression of SOX9, COL2A1, and COMP in circulating progenitor cells following a half marathon (HM) performance. Therefore, we studied in-depth the involvement of metabolites affecting chondrocyte lineage, and we compared the metabolomic profile associated with PA by analyzing runners’ sera before and after HM performance. …”
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Physical Exercise Modulates miR-21-5p, miR-129-5p, miR-378-5p, and miR-188-5p Expression in Progenitor Cells Promoting Osteogenesis by Maria Teresa Valenti, Michela Deiana, Samuele Cheri, Monica Dotta, Francesco Zamboni, Daniele Gabbiani, Federico Schena, Luca Dalle Carbonare, Monica Mottes

“…In this study, we recruited 20 male amateur runners participating in a half marathon. Runners’ sera, collected before (PRE RUN) and after (POST RUN) the run, were added to cultured human mesenchymal stromal cells. …”
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