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NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity
Published 2023-07-01“…Here, we utilized peripheral blood specimens from the Improving Retreatment Success CAPRISA 011 study to characterize NK cell phenotypes during active TB in individuals with or without HIV co-infection. …”
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Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis
Published 2023-08-01“…Methods Plasma samples were obtained from 128 participants from the CAPRISA 020 Individualized M(X)drug-resistant TB Treatment Strategy Study (InDEX) prior to treatment initiation. …”
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Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection
Published 2023-07-01“…Using flow cytometry, we characterized the frequencies and phenotypic differences in monocytes and dendritic cell populations using peripheral blood mononuclear cells from individuals with recurrent, active pulmonary tuberculosis with and without coexisting HIV infection (CAPRISA 011, Clinicaltrials.gov, NCT02114684, 29/01/2014) and compared them to samples from HIV positive individuals and healthy controls. …”
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Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance
Published 2023-12-01Get full text
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