MR spectroscopy in heart failure. by Holloway, C, ten Hove, M, Clarke, K, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) is an established technique for the non-invasive assessment of myocardial metabolism. …”

Cardiac magnetic resonance spectroscopy. by Neubauer, S

“…This review describes recent advances in cardiac magnetic resonance spectroscopy (MRS). MRS allows noninvasive characterization of the metabolic state of cardiac muscle, in both animal and human models. …”

Clinical cardiac magnetic resonance spectroscopy. by Holloway, C, Suttie, J, Dass, S, Neubauer, S

“…Cardiac magnetic resonance spectroscopy (MRS) is a noninvasive tool for the assessment of myocardial metabolism, without the use of radiation or intravenous contrast agents. …”

[Clinical relevance of MR spectroscopy of the heart] by Neubauer, S

“…MR spectroscopy is the only method that allows for the noninvasive study of cardiac metabolism in the human heart without the use of external radioactive tracers. 31P-spectroscopy allows to examine the high-energy phosphates ATP and phosphocreatine. …”

Magnetic resonance spectroscopy in myocardial disease. by Hudsmith, L, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) is the only noninvasive, nonradiation exposure technique for the investigation of cardiac metabolism in vivo. …”

Metabolic imaging with cardiac magnetic resonance spectroscopy by Neubauer, S

“…The only non invasive technique for the assessment of cardiac metabolism in patients that does not use radiation is magnetic resonance spectroscopy (MRS). By interrogating signals from phosphorus-31 and hydrogen-1, spectroscopy offers a wealth of metabolic information on the heart muscle. …”

Detection of myocardial disorders by magnetic resonance spectroscopy. by Hudsmith, L, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) utilizes magnetic resonance signals from nuclei, such as phosphorus-31, to provide information regarding the biochemical composition and metabolic state of cardiac muscle. …”

[Experimental and clinical possibilities of MR spectroscopy of the heart] by Neubauer, S, Ertl, G, Krahe, T, Schindler, R, Hillenbrand, H, Lackner, K, Kochsiek, K

“…MR-spectroscopy of the heart is a relatively new technique for the study of various aspects of cardiac metabolism. …”

Experimental and clinical possibilities of MR spectroscopy of the heart by Neubauer, S, Ertl, G, Krahe, T, Schindler, R, Hillenbrand, H, Lackner, K, Kochsiek, K

“…MR-spectroscopy of the heart is a relatively new technique for the study of various aspects of cardiac metabolism. …”

The application of NMR spectroscopy for the study of heart failure. by ten Hove, M, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) has been used for several decades to examine the biochemistry of the myocardium in a non destructive manner. (31)P MRS, in particular, has been used to study heart failure. (31)P MRS allows for the detection of adenosine triphosphate (ATP), the primary energy source for all energy consuming processes in cardiomyocytes, and phosphocreatine (PCr). …”

Human cardiac MR spectroscopy--clinical methods and applications. by Beer, M, Hahn, D, Neubauer, S

[31P-cardio-MR-spectroscopy in myocardial insufficiency] by Krahe, T, Schindler, R, Neubauer, S, Ertl, G, Horn, M, Lackner, K

“…The relative linear relationships of creatine phosphate/gamma-adenosine triphosphate (PCr/ATP) and of phosphodiester (PDE)/ATP were measured in 38 normals and 27 patients with cardiac insufficiency using cardiac 31P-MR-spectroscopy. There was no significant difference between normals and those with dilated cardiomyopathy (19 cases) and severe aortic valve lesions (8 cases), irrespective of the clinical stage of the cardiac abnormality. …”

MR spectroscopy in heart failure--clinical and experimental findings. by Ten Hove, M, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) allows for the non-invasive detection of a wide variety of metabolites in the heart. …”

Cardiac 31P-MR-spectroscopy in myocardial insufficiency by Krahe, T, Schindler, R, Neubauer, S, Ertl, G, Horn, M, Lackner, K

“…The relative linear relationships of creatin phosphate/γ-adenosin triphosphate (PCr/ATP) and of phosphodiester (PDE)/ATP were measured in 38 normals and 27 patients with cardiac insufficiency using cardiac 31P-MR-spectroscopy. There was no significant difference between normals and those with dilated cardiomyopathy (19 cases) and severe aortic valve lesions (8 cases), irrespective of the clinical stage of the cardiac abnormality. …”

[Magnetic resonance spectroscopy of the heart. Its clinical importance] by Neubauer, S, Horn, M, Ertl, G, Kochsiek, K

Dilated Cardiomyopathy: Phosphorus 31 MR Spectroscopy at 7 T by Stoll, V, Clarke, W, Levelt, E, Liu, A, Myerson, S, Robson, M, Neubauer, S, Rodgers, C

“…<strong>Purpose:</strong> This study is designed to test whether the increased 31P spectroscopy signal-to-noise ratio at 7T, compared to 3T field strength, improves precision in cardiac metabolite quantification in dilated cardiomyopathy patients. …”

Cardiac magnetic resonance spectroscopy: potential clinical applications. by Neubauer, S

“…MR spectroscopy is the only method for non-invasive detection of various aspects of cardiac metabolism in humans. …”

Evaluating metabolic changes in heart disease by magnetic resonance spectroscopy by Ten Hove, M, Neubauer, S

“…Magnetic resonance spectroscopy (MRS) is a versatile and powerful tool for the non invasive study of cardiac metabolism and can be used to measure myocardial concentrations of many different metabolites. …”

Reproducibility of 31P cardiac magnetic resonance spectroscopy at 3 T. by Tyler, D, Emmanuel, Y, Cochlin, L, Hudsmith, L, Holloway, C, Neubauer, S, Clarke, K, Robson, M

(1)H-MR spectroscopy for analysis of cardiac lipid and creatine metabolism. by Faller, K, Lygate, C, Neubauer, S, Schneider, J

“…Magnetic resonance spectroscopy (MRS) is the only non-invasive, non-radiation-based technique for investigating the metabolism of living tissue. …”