Amount of DNA in plasma and cancer risk: a prospective study. by Gormally, E, Hainaut, P, Caboux, E, Airoldi, L, Autrup, H, Malaveille, C, Dunning, A, Garte, S, Matullo, G, Overvad, K, Tjonneland, A, Clavel-Chapelon, F, Boffetta, P, Boeing, H, Trichopoulou, A, Palli, D, Krogh, V, Tumino, R, Panico, S, Bueno-de-Mesquita, H, Peeters, P, Lund, E, Gonzalez, C, Martinez, C, Dorronsoro, M

“…When the analyses were stratified by time since recruitment (below or above 36 months), the increased ORs were limited to the more recent period of recruitment, i.e., a time elapsed between blood drawing and disease onset lower than 36 months. …”

Air pollution and risk of lung cancer in a prospective study in Europe. by Vineis, P, Hoek, G, Krzyzanowski, M, Vigna-Taglianti, F, Veglia, F, Airoldi, L, Autrup, H, Dunning, A, Garte, S, Hainaut, P, Malaveille, C, Matullo, G, Overvad, K, Raaschou-Nielsen, O, Clavel-Chapelon, F, Linseisen, J, Boeing, H, Trichopoulou, A, Palli, D, Peluso, M, Krogh, V, Tumino, R, Panico, S, Bueno-De-Mesquita, H, Peeters, P

“…Matching criteria were gender, age (+/-5 years), smoking status, country of recruitment and time elapsed between recruitment and diagnosis. …”

Amount of DNA in plasma and cancer risk: A prospective study by Gormally, E, Hainaut, P, Caboux, E, Airoldi, L, Autrup, H, Malaveille, C, Dunning, A, Garte, S, Matullo, G, Overvad, K, Tjonneland, A, Clavel-Chapelon, F, Boffetta, P, Boeing, H, Trichopoulou, A, Palli, D, Krogh, V, Tumino, R, Panico, S, Bueno-De-Mesquita, H, Peeters, P, Lund, E, Gonzalez, C, Martinez, C, Dorronsoro, M

“…When the analyses were stratified by time since recruitment (below or above 36 months), the increased ORs were limited to the more recent period of recruitment, i.e., a time elapsed between blood drawing and disease onset lower than 36 months. …”

Air pollution and risk of lung cancer in a prospective study in Europe by Vineis, P, Hoek, G, Krzyzanowski, M, Vigna-Taglianti, F, Veglia, F, Airoldi, L, Autrup, H, Dunning, A, Garte, S, Hainaut, P, Malaveille, C, Matullo, G, Overvad, K, Raaschou-Nielsen, O, Clavel-Chapelon, F, Linseisen, J, Boeing, H, Trichopoulou, A, Palli, D, Peluso, M, Krogh, V, Tumino, R, Panico, S, Bas Bueno-De-Mesquita, H, Peeters, P

“…Matching criteria were gender, age (±5 years), smoking status, country of recruitment and time elapsed between recruitment and diagnosis. …”

Sources of pre-analytical variations in yield of DNA extracted from blood samples: analysis of 50,000 DNA samples in EPIC. by Caboux, E, Lallemand, C, Ferro, G, Hémon, B, Mendy, M, Biessy, C, Sims, M, Wareham, N, Britten, A, Boland, A, Hutchinson, A, Siddiq, A, Vineis, P, Riboli, E, Romieu, I, Rinaldi, S, Gunter, M, Peeters, P, van der Schouw, Y, Travis, R, Bueno-de-Mesquita, H, Canzian, F, Sánchez, M, Skeie, G, Olsen, K, Lund, E, Bilbao, R, Sala, N, Barricarte, A, Palli, D, Navarro, C, Panico, S, Redondo, M, Polidoro, S, Dossus, L, Boutron-Ruault, M, Clavel-Chapelon, F, Trichopoulou, A, Trichopoulos, D, Lagiou, P, Boeing, H, Fisher, E, Tumino, R, Agnoli, C, Hainaut, P

“…We show that the largest significant variations in DNA yield were observed with degree of haemolysis and with center of subject recruitment. Age, gender, body-mass index, cancer case or control status and tobacco consumption also significantly impacted DNA yield. …”

Alcohol consumption and the risk for prostate cancer in the European Prospective Investigation into Cancer and Nutrition. by Rohrmann, S, Linseisen, J, Key, T, Jensen, M, Overvad, K, Johnsen, N, Tjønneland, A, Kaaks, R, Bergmann, M, Weikert, C, Naska, A, Trichopoulou, A, Trichopoulos, D, Pala, V, Sacerdote, C, Palli, D, Tumino, R, Bueno-de-Mesquita, H, Vrieling, A, González, C, Larrañaga, N, Navarro, C, Barricarte, A, Quiros, JR, Martínez-García, C

“…Within the European Prospective Investigation into Cancer and Nutrition, detailed information were collected from 142,607 male participants on the intake of alcoholic beverages at recruitment (for 100% of the cohort) and over lifetime (for 76% of the cohort) between 1992 and 2000. …”

Prediagnostic concentrations of plasma genistein and prostate cancer risk in 1,605 men with prostate cancer and 1,697 matched control participants in EPIC. by Travis, R, Allen, N, Appleby, P, Price, A, Kaaks, R, Chang-Claude, J, Boeing, H, Aleksandrova, K, Tjønneland, A, Johnsen, N, Overvad, K, Ramón Quirós, J, González, C, Molina-Montes, E, Sánchez, M, Larrañaga, N, Castaño, J, Ardanaz, E, Khaw, K, Wareham, N, Trichopoulou, A, Karapetyan, T, Rafnsson, S, Palli, D, Krogh, V

“…There was no evidence of heterogeneity in this association by age at blood collection, country of recruitment, or cancer stage or histological grade. …”

Macronutrient intake and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition by Allen, N, Appleby, P, Key, T, Bueno-De-Mesquita, H, Ros, M, Kiemeney, L, Tjønneland, A, Roswall, N, Overvad, K, Weikert, S, Boeing, H, Chang-Claude, J, Teucher, B, Panico, S, Sacerdote, C, Tumino, R, Palli, D, Sieri, S, Peeters, P, Quirós, JR, Jakszyn, P, Molina-Montes, E, Chirlaque, M, Ardanaz, E, Dorronsoro, M

“…Associations were examined using Cox regression, stratified by sex, age at recruitment and centre and further adjusted for smoking status and duration, body mass index and total energy intake. …”

Animal foods, protein, calcium and prostate cancer risk: the European Prospective Investigation into Cancer and Nutrition. by Allen, N, Key, T, Appleby, P, Travis, R, Roddam, A, Tjønneland, A, Johnsen, N, Overvad, K, Linseisen, J, Rohrmann, S, Boeing, H, Pischon, T, Bueno-de-Mesquita, H, Kiemeney, L, Tagliabue, G, Palli, D, Vineis, P, Tumino, R, Trichopoulou, A, Kassapa, C, Trichopoulos, D, Ardanaz, E, Larrañaga, N, Tormo, M, González, C

“…Associations were examined using Cox regression, stratified by recruitment centre and adjusted for height, weight, education, marital status and energy intake. …”

Plasma phyto-oestrogens and prostate cancer in the European Prospective Investigation into Cancer and Nutrition. by Travis, R, Spencer, E, Allen, N, Appleby, P, Roddam, A, Overvad, K, Johnsen, N, Olsen, A, Kaaks, R, Linseisen, J, Boeing, H, Nöthlings, U, Bueno-de-Mesquita, H, Ros, M, Sacerdote, C, Palli, D, Tumino, R, Berrino, F, Trichopoulou, A, Dilis, V, Trichopoulos, D, Chirlaque, MD, Ardanaz, E, Larranaga, N, Gonzalez, C

“…There was no evidence of heterogeneity in these results by age at blood collection or country of recruitment, nor by cancer stage or grade. These results suggest that higher concentrations of circulating genistein may reduce the risk of prostate cancer but do not support an association with plasma lignans.…”

Macronutrient intake and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition. by Allen, N, Appleby, P, Key, T, Bueno-de-Mesquita, H, Ros, M, Kiemeney, L, Tjønneland, A, Roswall, N, Overvad, K, Weikert, S, Boeing, H, Chang-Claude, J, Teucher, B, Panico, S, Sacerdote, C, Tumino, R, Palli, D, Sieri, S, Peeters, P, Quirós, JR, Jakszyn, P, Molina-Montes, E, Chirlaque, MD, Ardanaz, E, Dorronsoro, M

“…Associations were examined using Cox regression, stratified by sex, age at recruitment and centre and further adjusted for smoking status and duration, body mass index and total energy intake. …”

Longitudinal changes in weight in relation to smoking cessation in participants of the EPIC-PANACEA study. by Travier, N, Agudo, A, May, A, Gonzalez, C, Luan, J, Wareham, N, Bueno-de-Mesquita, H, van den Berg, S, Slimani, N, Rinaldi, S, Clavel-Chapelon, F, Boutron-Ruault, M, Palli, D, Sieri, S, Mattiello, A, Tumino, R, Vineis, P, Norat, T, Romaguera, D, Rodriguez, L, Sanchez, M, Dorronsoro, M, Barricarte, A, Huerta, J, Key, T

“…When smokers who stopped smoking at least 1 year before recruitment were compared to never smokers, no major differences in annual weight gain were observed. …”

Dietary patterns and survival of older Europeans: the EPIC-Elderly Study (European Prospective Investigation into Cancer and Nutrition). by Bamia, C, Trichopoulos, D, Ferrari, P, Overvad, K, Bjerregaard, L, Tjønneland, A, Halkjaer, J, Clavel-Chapelon, F, Kesse, E, Boutron-Ruault, M, Boffetta, P, Nagel, G, Linseisen, J, Boeing, H, Hoffmann, K, Kasapa, C, Orfanou, A, Travezea, C, Slimani, N, Norat, T, Palli, D, Pala, V, Panico, S, Tumino, R, Sacerdote, C

“…Cox regression analysis was used to investigate the association of the prevailing, a posteriori-derived, plant-based dietary pattern with all-cause mortality in a population of subjects who were 60 years or older at recruitment to the European Prospective Investigation into Cancer and Nutrition (EPIC-Elderly cohort). …”

Plasma phytanic acid concentration and risk of prostate cancer: results from the European Prospective Investigation into Cancer and Nutrition. by Price, A, Allen, N, Appleby, P, Crowe, F, Jenab, M, Rinaldi, S, Slimani, N, Kaaks, R, Rohrmann, S, Boeing, H, Pischon, T, Benetou, V, Naska, A, Trichopoulou, A, Palli, D, Sieri, S, Tumino, R, Vineis, P, Bueno-de-Mesquita, H, Donate, I, González, C, Sánchez, M, Chirlaque, MD, Ardanaz, E, Larrañaga, N

“…DESIGN: Within the European Prospective Investigation into Cancer and Nutrition cohort, 566 incident prostate cancer cases from Germany, Greece, Italy, the Netherlands, Spain, and the United Kingdom were individually matched to 566 controls by study center, age at recruitment, and time of day and duration of fasting at blood collection. …”

Concentrations of IGF-I and IGFBP-3 and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. by Rohrmann, S, Grote, V, Becker, S, Rinaldi, S, Tjønneland, A, Roswall, N, Grønbæk, H, Overvad, K, Boutron-Ruault, M, Clavel-Chapelon, F, Racine, A, Teucher, B, Boeing, H, Drogan, D, Dilis, V, Lagiou, P, Trichopoulou, A, Palli, D, Tagliabue, G, Tumino, R, Vineis, P, Mattiello, A, Rodríguez, L, Duell, E, Molina-Montes, E

“…METHODS: Serum concentrations of IGF-I and IGFBP-3 were measured using enzyme-linked immunosorbent assays in 422 cases and 422 controls matched on age, sex, study centre, recruitment date, and time since last meal. Conditional logistic regression was used to compute odds ratios (OR) and 95% confidence intervals (CI) adjusted for confounding variables. …”

Plasma phytanic acid concentration and risk of prostate cancer: Results from the European prospective investigation into cancer and nutrition by Price, A, Allen, N, Appleby, P, Crowe, F, Jenab, M, Rinaldi, S, Slimani, N, Kaaks, R, Rohrmann, S, Boeing, H, Pischon, T, Benetou, V, Naska, A, Trichopoulou, A, Palli, D, Sieri, S, Tumino, R, Vineis, P, Bueno-de-Mesquita, H, Donate, I, González, C, Sánchez, M, Chirlaque, M, Ardanaz, E, Larrañaga, N

“…Design: Within the European Prospective Investigation into Cancer and Nutrition cohort, 566 incident prostate cancer cases from Germany, Greece, Italy, the Netherlands, Spain, and the United Kingdom were individually matched to 566 controls by study center, age at recruitment, and time of day and duration of fasting at blood collection. …”

Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition. by Travis, R, Appleby, P, Siddiq, A, Allen, N, Kaaks, R, Canzian, F, Feller, S, Tjønneland, A, Føns Johnsen, N, Overvad, K, Ramón Quirós, J, González, C, Sánchez, M, Larrañaga, N, Chirlaque, MD, Barricarte, A, Khaw, K, Wareham, N, Trichopoulou, A, Valanou, E, Oustoglou, E, Palli, D, Sieri, S, Tumino, R, Sacerdote, C

“…Intake of milk and total dairy products varied significantly by lactase genotype after adjustment for recruitment center; adjusted mean intakes of milk were 44.4, 69.8 and 82.3 g/day among men with CC, CT and TT genotypes, respectively. …”

Circulating 25-hydroxyvitamin D3 in relation to renal cell carcinoma incidence and survival in the EPIC cohort. by Muller, D, Fanidi, A, Midttun, Ø, Steffen, A, Dossus, L, Boutron-Ruault, M, Severi, G, Kühn, T, Katzke, V, de la Torre, R, González, C, Sánchez, M, Dorronsoro, M, Santiuste, C, Barricarte, A, Khaw, K, Wareham, N, Travis, R, Trichopoulou, A, Giotaki, M, Trichopoulos, D, Palli, D, Krogh, V, Tumino, R, Vineis, P

“…We assessed whether 25-hydroxyvitamin D3 (25(OH)D3) was associated with risk of RCC and death after RCC diagnosis in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC recruited 385,747 participants with blood samples between 1992 and 2000. …”

Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. by Key, T, Appleby, P, Allen, N, Travis, R, Roddam, A, Jenab, M, Egevad, L, Tjønneland, A, Johnsen, N, Overvad, K, Linseisen, J, Rohrmann, S, Boeing, H, Pischon, T, Psaltopoulou, T, Trichopoulou, A, Trichopoulos, D, Palli, D, Vineis, P, Tumino, R, Berrino, F, Kiemeney, L, Bueno-de-Mesquita, H, Quirós, JR, González, C

“…A total of 1064 control subjects were selected and were matched for study center, age, and date of recruitment. The relative risk of prostate cancer was estimated by conditional logistic regression, which was adjusted for smoking status, alcohol intake, body mass index, marital status, physical activity, and education level. …”

Fruits and vegetables and prostate cancer: no association among 1104 cases in a prospective study of 130544 men in the European Prospective Investigation into Cancer and Nutrition... by Key, T, Allen, N, Appleby, P, Overvad, K, Tjønneland, A, Miller, A, Boeing, H, Karalis, D, Psaltopoulou, T, Berrino, F, Palli, D, Panico, S, Tumino, R, Vineis, P, Bueno-De-Mesquita, H, Kiemeney, L, Peeters, P, Martinez, C, Dorronsoro, M, González, C, Chirlaque, MD, Quiros, JR, Ardanaz, E, Berglund, G, Egevad, L

“…Data on food consumption and complete follow-up for cancer incidence were available for 130544 men in 7 countries recruited into EPIC between 1993 and 1999. After an average of 4.8 years of follow-up, there were 1104 incident cases of prostate cancer. …”