Rapid Molecular Assays for the Diagnosis of Drug-Resistant Tuberculosis by Nandlal L, Perumal R, Naidoo K

“…Louansha Nandlal,* Rubeshan Perumal,* Kogieleum Naidoo* Centre for the AIDS Programme of Research in South Africa (CAPRISA), South African Medical Research Council (SAMRC)-CAPRISA-TB-HIV Pathogenesis and Treatment Research Unit, University of KwaZulu-Natal Nelson R Mandela School of Medicine, Durban, South Africa*These authors contributed equally to this workCorrespondence: Rubeshan Perumal, Centre for the AIDS Programme of Research in South Africa (CAPRISA), South African Medical Research Council (SAMRC)-CAPRISA-TB-HIV Pathogenesis and Treatment Research Unit, University of KwaZulu-Natal Nelson R Mandela School of Medicine, Durban, South Africa, Email Rubeshan.Perumal@caprisa.orgAbstract: The recognition that drug-resistant tuberculosis (DR-TB) poses a major threat to global tuberculosis (TB) control efforts has catalysed the development of new and urgently needed TB diagnostics. …”
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Drug-Resistant TB, HIV and COVID-19 Co-Infection: Case Reviews from Kwa-Zulu Natal, South Africa by Hassan-Moosa R, Motsomi KW, Narasimmulu R, Sivro A, Naidu KK, Kharsany ABM, Samsunder N, Perumal R, Naidoo K

“…Razia Hassan-Moosa,1,2 Kegaugetswe Wilhemina Motsomi,1 Radhamoney Narasimmulu,1 Aida Sivro,1,3– 5 Kevindra K Naidu,1 Ayesha BM Kharsany,1,3 Natasha Samsunder,1 Rubeshan Perumal,1,2 Kogieleum Naidoo1,2 1Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; 2MRC-CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; 3Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa; 4JC Wilt Infectious Disease Research Centre, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; 5Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, CanadaCorrespondence: Kegaugetswe Wilhemina Motsomi, Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal Nelson R Mandela School of Medicine, Private Bag X7, Congella, Durban, 4013, South Africa, Email pinky.motsomi@caprisa.orgBackground: Coronavirus disease (COVID-19) potentially exacerbates drug-resistant tuberculosis (DR-TB). …”
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Mycobacterium tuberculosis Intra-Host Evolution Among Drug-Resistant Tuberculosis Patients Failing Treatment by Perumal R, Khan A, Naidoo K, Ngema SL, Nandlal L, Padayatchi N, Dookie N

“…Rubeshan Perumal,1,2 Azraa Khan,1 Kogieleum Naidoo,1,2 Senamile L Ngema,1 Louansha Nandlal,1,2 Nesri Padayatchi,1,2 Navisha Dookie1,2 1Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, KwaZulu Natal, South Africa; 2South African Medical Research Council (SAMRC) – CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Durban, KwaZulu Natal, South AfricaCorrespondence: Rubeshan Perumal, Doris Duke Medical Research Institute (2nd Floor), Nelson R. …”
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Metformin Increases Cell Viability and Regulates Pro-Inflammatory Response to Mtb by Naicker N, Rodel H, Perumal R, Ganga Y, Bernstein M, Benede N, Abdool Karim S, Padayacthi N, Sigal A, Naidoo K

“…Nikita Naicker,1 Hylton Rodel,2 Rubeshan Perumal,1 Yashica Ganga,2 Mallory Bernstein,2 Ntombi Benede,2 Salim Abdool Karim,1,3 Nesri Padayacthi,1,3 Alex Sigal,2,4,5 Kogieleum Naidoo1,3 1Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; 2Africa Health Research Institute, Durban, South Africa; 3MRC-CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute; University of KwaZulu-Natal, Durban, South Africa; 4School of Laboratory Medicine and Medical Sciences; University of KwaZulu-Natal, Durban, South Africa; 5Max Planck Institute for Infection Biology, Berlin, GermanyCorrespondence: Nikita Naicker, Doris Duke Medical Research Institute, 2nd Floor, 719 Umbilo Road, Durban, 4041, South Africa, Tel +27843011636, Email nikita.naicker@caprisa.orgIntroduction: Current TB treatment regimens are pathogen-directed and can be severely compromised by the development of drug resistance. …”
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