Advances in PET and MRI imaging of tumor hypoxia by Pierrick Gouel, Pierrick Gouel, Pierre Decazes, Pierre Decazes, Pierre Vera, Pierre Vera, Isabelle Gardin, Isabelle Gardin, Sébastien Thureau, Sébastien Thureau, Pierre Bohn, Pierre Bohn

“…Different ways of imaging hypoxia are discussed in this review, with nuclear medicine tracers such as [18F]-FMISO, [18F]-FAZA, or [64Cu]-ATSM but also with MRI techniques such as perfusion imaging, diffusion MRI or oxygen-enhanced MRI. Hypoxia is a pejorative factor regarding aggressiveness, tumor dissemination and resistance to treatments. …”
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Synergic prognostic value of 3D CT scan subcutaneous fat and muscle masses for immunotherapy-treated cancer by Caroline Robert, Aurélien Marabelle, Fabrice Barlesi, Samy Ammari, David Planchard, Siham Farhane, Paul-Henry Cournède, Pierre Decazes, Younes Belkouchi, Léo Mottay, Littisha Lawrance, Antoine de Prévia, Hugues Talbot, Florian Guisier, Tony Ibrahim, Pierre Vera, Nathalie Lassau

“…On the external validation cohort, combination of low SFM and low MBM was pejorative with 63% of mortality at 1 year versus 25% (p=0.0029).Conclusions 3D measured low SFM and MBM are significant prognosis factors of NSCLC treated by immune checkpoint inhibitors and can be combined to improve the prognostic value.…”
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