Showing 1 - 6 results of 6 for search '"human liver"', query time: 0.08s Refine Results
  1. 1
    Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

    Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol by Pil Joung Cho, Sanjita Paudel, Doohyun Lee, Yun Ji Jin, GeunHyung Jo, Tae Cheon Jeong, Sangkyu Lee, Taeho Lee

    Published 2018-08-01
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  2. 2
    Metabolism of Diterpenoids Derived from the Bark of <i>Cinnamomum cassia</i> in Human Liver Microsomes

    Metabolism of Diterpenoids Derived from the Bark of <i>Cinnamomum cassia</i> in Human Liver Microsomes by Su Min Choi, Van Cong Pham, Sangkyu Lee, Jeong Ah Kim

    Published 2021-08-01
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  3. 3
    Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation

    Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation by Riya Shrestha, Pil Joung Cho, Sanjita Paudel, Aarajana Shrestha, Mi Jeong Kang, Tae Cheon Jeong, Eung-Seok Lee, Sangkyu Lee

    Published 2018-08-01
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  4. 4
    Nontargeted Metabolomics by High-Resolution Mass Spectrometry to Study the In Vitro Metabolism of a Dual Inverse Agonist of Estrogen-Related Receptors β and γ, DN203368

    Nontargeted Metabolomics by High-Resolution Mass Spectrometry to Study the In Vitro Metabolism of a Dual Inverse Agonist of Estrogen-Related Receptors β and γ, DN203368 by Sin-Eun Kim, Seung-Bae Ji, Euihyeon Kim, Minseon Jeong, Jina Kim, Gyung-Min Lee, Hyung-Ju Seo, Subin Bae, Yeojin Jeong, Sangkyu Lee, Sunghwan Kim, Taeho Lee, Sung Jin Cho, Kwang-Hyeon Liu

    Published 2021-05-01
    “…Only five metabolites (M2, M3, and M5-M7) were detected in human liver microsomes. In the conventional approach using extracted ion monitoring for values of mass increase or decrease by known metabolic reactions, only five metabolites (M1-M5) were found in rat liver microsomes, whereas three metabolites (M2, M3, and M5) were found in human liver microsomes. …”
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  5. 5
    Revisiting the Metabolism and Bioactivation of Ketoconazole in Human and Mouse Using Liquid Chromatography–Mass Spectrometry-Based Metabolomics

    Revisiting the Metabolism and Bioactivation of Ketoconazole in Human and Mouse Using Liquid Chromatography–Mass Spectrometry-Based Metabolomics by Ju-Hyun Kim, Won-Gu Choi, Sangkyu Lee, Hye Suk Lee

    Published 2017-03-01
    “…Moreover, three cyanide adducts of KCZ were identified in mouse and human liver microsomal incubates as “flags” to trigger additional toxicity study. …”
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  6. 6
    In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics

    In Vitro Metabolism of Donepezil in Liver Microsomes Using Non-Targeted Metabolomics by Sin-Eun Kim, Hyung-Ju Seo, Yeojin Jeong, Gyung-Min Lee, Seung-Bae Ji, So-Young Park, Zhexue Wu, Sangkyu Lee, Sunghwan Kim, Kwang-Hyeon Liu

    Published 2021-06-01
    “…A total of 21 donepezil metabolites (17 in human liver microsomes, 21 in mice liver microsomes, and 17 in rat liver microsomes) were detected including 14 newly identified metabolites. …”
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