Self-assembled nanostructures of red fluorescent amphiphilic block copolymers as both imaging probes and drug carriers by Huang, Shuo, Wei, Xin, Wang, Mingfeng

“…Two types of polylactones, i.e., semicrystalline poly(ε-caprolactone) (PCL) and amorphous poly(δ-decalactone) (PDL), respectively, were incorporated as the hydrophobic segment in the block copolymers. Using transmission electron microscopy, we characterized the self-assembled nanostructures formed by these amphiphilic block copolymers in mixtures of water/tetrahydrofuran or water/dimethylformamide. …”
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Block copolymer nanoparticles remove biofilms of drug-resistant gram-positive bacteria by nanoscale bacterial debridement by Li, Jianghua, Zhang, Kaixi, Ruan, Lin, Chin, Seow Fong, Wickramasinghe, Nirmani, Liu, Hanbin, Ravikumar, Vikashini, Ren, Jinghua, Duan, Hongwei, Yang, Liang, Chan-Park, Mary Bee Eng

“…In this Letter, we show that the block copolymer DA95B5, dextran-block-poly((3-acrylamidopropyl) trimethylammonium chloride (AMPTMA)-co-butyl methacrylate (BMA)), effectively removes preformed biofilms of various clinically relevant multidrug-resistant Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE V583), and Enteroccocus faecalis (OG1RF). …”
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Caging cationic polymer brush-coated plasmonic nanostructures for traceable selective antimicrobial activities by Ma, Jielin, Hou, Shuai, Lu, Derong, Zhang, Bo, Xiong, Qirong, Chan-Park, Mary B., Duan, Hongwei

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DNA-derived nanostructures selectively capture gram-positive bacteria by Kim, Chan-Jin, Si, Zhangyong, Reghu, Sheethal, Guo, Zhong, Zhang, Kaixi, Li, Jianghua, Chan-Park, Mary B.

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Self-assembled plasmonic vesicles of amphiphilic gold nanocrystals for traceable drug delivery by Song, Jibin

“…The integration of gold nanocrystals with two types of chemically distinct polymer grafts, which are analogous to block copolymers as a whole, creates a new type of hybrid building blocks inheriting the amphiphilicity-driven self-assembly of block copolymers to form vesicular structures. …”
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Theranostic unimolecular micelles of highly fluorescent conjugated polymer bottlebrushes for far red/near infrared bioimaging and efficient anticancer drug delivery by Yang, Cangjie, Huang, Shuo, Wang, Xiaochen, Wang, Mingfeng

“…The amphiphilic and branched nature of these grafted block copolymers enabled the formation of unimolecular micelles (UMs) that were well dispersible in aqueous media. …”
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Synthesis and antibacterial study of sulfobetaine/quaternary ammonium-modified star-shaped poly[2-(dimethylamino)ethyl methacrylate]-based copolymers with an inorganic core by Pu, Yuji, Hou, Zheng, Khin, Mya Mya, Zamudio-Vázquez, Rubi, Poon, Kar Lai, Duan, Hongwei, Chan-Park, Mary B.

“…The random cationic-zwitterionic polymers showed poor antibacterial activity while the block polymers retained the antibacterial activity of the pristine POSS-g-PDMA. The block copolymers of POSS-g-(PDMA-b-polysulfobetaine) showed enhanced antifouling property and serum stability as seen by their nanoparticle size stability in the presence of serum and reduced red blood cell aggregation. …”
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Precisely structured nitric-oxide-releasing copolymer brush defeats broad-spectrum catheter-associated biofilm infections in vivo by Hou, Zheng, Wu, Yang, Xu, Chen, Reghu, Sheethal, Shang, Zifang, Chen, Jingjie, Pranantyo, Dicky, Marimuth, Kalisvar, De, Partha Pratim, Ng, Oon Tek, Pethe, Kevin, Kang, En-Tang, Li, Peng, Chan-Park, Mary B.

“…The coating procedure is scalable to clinically useful catheter lengths. Only the block copolymer brush coating ((H(N)-b-S)) shows unprecedented, above 99.99%, in vitro biofilm inhibition of Gram-positive and Gram-negative bacteria, 100-fold better than previous coatings. …”
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Assembly and photochemical properties of mesoporous networks of spinel ferrite nanoparticles for environmental photocatalytic remediation by Skliri, Euaggelia, Miao, Jianwei, Xie, Jian, Liu, Guangfeng, Salim, Teddy, Liu, Bin, Zhang, Qichun, Armatas, Gerasimos S.

“…Revealed by electron microscopy, N2 physisorption, and X-ray scattering studies, the resulting materials, which were obtained through a block copolymer-assisted cross-linking aggregation of colloidal nanoparticles, show a 3D interconnected nanoporous structure with a large internal surface area (up to 159 m2 g−1) and exhibit small grain composition (ca. 6–8 nm in size). …”
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