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Characterization of metabolite profile in Phyllanthus niruri and correlation with bioactivity elucidated by nuclear magnetic resonance based metabolomics
Published 2017“…Herein, three dried P. niruri samples, air (AD), freeze (FD) and oven (OD), extracted with various ethanol to water ratios (0%, 50%, 70%, 80% and 100%) were evaluated for their metabolite changes using proton nuclear magnetic resonance (1H-NMR)-based metabolomics approach. …”
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Characterization of metabolite profile in Phyllanthus niruri and correlation with bioactivity elucidated by nuclear magnetic resonance based metabolomics
Published 2017“…Herein, three dried P. niruri samples, air (AD), freeze (FD) and oven (OD), extracted with various ethanol to water ratios (0%, 50%, 70%, 80% and 100%) were evaluated for their metabolite changes using proton nuclear magnetic resonance (¹H-NMR)-based metabolomics approach. …”
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A preliminary nuclear magnetic resonance metabolomics study identifies metabolites that could serve as diagnostic markers of major depressive disorder
Published 2022“…Methodology: Eight (8) urine and serum samples each obtained from consenting healthy controls (HC), twenty-five (25) urine and serum samples each from first episode treatment naïve MDD (TNMDD) patients, and twenty (22) urine and serum samples each s from treatment naïve MDD patients 2 weeks after SSRI treatment (TWMDD) were analysed for metabolites using proton nuclear magnetic resonance (1HNMR) spectroscopy. The evaluation of patients’ samples was carried out using Partial Least Squares Discriminant Analysis (PLS-DA) and Orthogonal Partial Least Square- Discriminant Analysis (OPLSDA) models. …”
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The immunostimulant effects of Isochrysis galbana supplemented diet on the spleen of red hybrid tilapia (Oreochromis spp.) evaluated by nuclear magnetic resonance metabolomics
Published 2022“…Then, the potential biomarkers for immunomodulatory properties were identified through metabolic changes in the spleen using the proton nuclear magnetic resonance (1 H NMR) metabolomics approach. …”
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Comparison of partial least squares and artificial neural network for the prediction of antioxidant activity in extract of pegaga (centella) varieties from H-1 nuclear magnetic resonance spectroscopy
Published 2013“…Multivariate data analysis of 1H Nuclear Magnetic Resonance spectra was applied for the prediction of antioxidant activity in five different Pegaga (C. asiatica (var 1), C. asiatica (var 2), C. asiatica (var 3) H. bonariensis and H. sibthorpioides) varieties. …”
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Comparison of Partial Least Squares and Artificial Neural Network for the prediction of antioxidant activity in extract of pegaga (centella) varieties from 1H Nuclear Magnetic Resonance spectroscopy.
Published 2013“…Multivariate data analysis of 1H Nuclear Magnetic Resonance spectra was applied for the prediction of antioxidant activity in five different Pegaga (C. asiatica (var 1), C. asiatica (var 2), C. asiatica (var 3) H. bonariensis and H. sibthorpioides) varieties. …”
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Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis
Published 2011“…The metabolomic fingerprinting analysis of the ethanolic extracts of leaves of M. ptelefolia was carried out using 1H Nuclear Magnetic Resonance (NMR) spectroscopy and multivariate data analysis in order to differentiate young and mature leaves and to evaluate the variation of their chemical composition. …”
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Discrimination of young and mature leaves of Melicope ptelefolia using 1H NMR and multivariate data analysis
Published 2011“…The metabolomic fingerprinting analysis of the ethanolic extracts of leaves of M. ptelefolia was carried out using 1H Nuclear Magnetic Resonance (NMR) spectroscopy and multivariate data analysis in order to differentiate young and mature leaves and to evaluate the variation of their chemical composition. …”
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Identification of α-glucosidase inhibitory compounds from Curcuma mangga fractions
Published 2020“…The extraction solvents used have a strong effect on the metabolite profile and the bioactivity of the extract. A nuclear magnetic resonance (NMR)-based metabolomics approach was used to differentiate the metabolite profiles of hexane, chloroform, ethyl acetate, and methanol fractions of C. mangga rhizomes and to correlate the metabolites with α-glucosidase inhibitory activity. …”
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1H-NMR-based metabolomics approach to understanding the drying effects on the phytochemicals in Cosmos caudatus
Published 2012“…medicinal herb to treat several maladies. Proton nuclear magnetic resonance (1H-NMR) combined with principal component analysis (PCA) and partial least-squares analysis (PLS) was applied to distinguish variations among C. caudatus materials processed with various drying techniques. …”
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Metabolite profiling of the microalgal diatom Chaetoceros calcitrans and correlation with antioxidant and nitric oxide inhibitory activities via 1H NMR-based metabolomics
Published 2018“…Metabolite profiling of the microalgal diatom, Chaetoceros calcitrans was conducted by using robust metabolomics tools, namely 1H nuclear magnetic resonance (NMR) spectroscopy coupled with multivariate data analysis (MVDA). …”
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Identification of the compositional changes in Orthosiphon stamineus leaves triggered by different drying techniques using 1H NMR metabolomics
Published 2017“…Herein, the impact of three commonly used drying methods, i.e. shade, microwave and freeze drying, on the metabolite composition and antioxidant activity of OS leaves was investigated using proton nuclear magnetic resonance (1H NMR) spectroscopy combined with multivariate classification and regression analysis tools. …”
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Discrimination of Ipomoea aquatica cultivars and bioactivity correlations using NMR-based metabolomics approach
Published 2017“…Different types of I. aquatica cultivars are grown for consumption but little is known about the metabolites variation. Proton nuclear magnetic resonance (1H NMR) spectroscopy combined with multivariate data analysis was applied for metabolic profiling of three I. aquatica cultivars including “broad leaf (K-25)”, “bamboo leaf (K-88)”, and “special pointed leaf (K-11)”. …”
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Classification of raw stingless bee honeys by bee species origins using the NMR- and LC-MS-based metabolomics approach
Published 2018“…Raw stingless bee honeys were analysed and classified by bee species origins using proton nuclear magnetic resonance (¹H-NMR) spectroscopy and an ultra-high performance liquid chromatography-quadrupole time of flight mass spectrometry (UHPLC-QTOF MS) in combination with chemometrics tools. …”
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Identification of nitric oxide inhibitory compounds from the rhizome of Curcuma xanthorrhiza
Published 2019“…This study profiles the metabolites in different fractions (hexane, chloroform, ethyl acetate and methanol) of the ethanolic extracts of C. xanthorrhiza using a nuclear magnetic resonance-based metabolomics approach. The nitric oxide (NO) inhibitory activity was determined using a Griess assay. …”
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Phytochemical and bioactivity alterations of Curcuma species harvested at different growth stages by NMR-based metabolomics
Published 2019“…This study aims to profile the metabolites in four Curcuma species, including C. zedoaria, C. xanthorrhiza, C. aeruginosa and C. mangga at three developmental stages (seven, eight and nine months old) using nuclear magnetic resonance (NMR)-based metabolomics. Principal component analysis (PCA) showed that there are metabolites changes due to the month of harvest in each of the four species. …”
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1H NMR-based metabolomics of Clinacanthus nutans leaves extracts in correlation with their anti-neuroinflammation towards LPS-induced BV2 cells
Published 2020“…Forty-four metabolites were putatively identified via proton Nuclear Magnetic Resonance (1H NMR and J-resolved NMR) metabolic profiling of CN leaf extracts in three types of solvents, namely water, 50% ethanol, and ethanol. …”
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