The energetics of protein-lipid interactions as viewed by molecular simulations by Corey, RA, Stansfeld, PJ, Sansom, M

“…This affords a more complete view of the engagement of a particular protein with the biological membrane surrounding it. Here, we describe many computational approaches currently in use for this purpose, including recent advances using both free energy and unbiased simulation methods. …”

A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates by Rao, S, Klesse, G, Stansfeld, PJ, Tucker, SJ, Sansom, M

“…Ion channel proteins control ionic flux across biological membranes through conformational changes in their transmembrane pores. …”

Water and hydrophobic gates in ion channels and nanopores by Rao, S, Lynch, C, Klesse, G, Oakley, GE, Stansfeld, PJ, Tucker, SJ, Sansom, MSP

“…Ion channel proteins form nanopores in biological membranes which allow the passage of ions and water molecules. …”