Locally coordinated synaptic plasticity of visual cortex neurons in vivo by El-Boustani, Sami, Ip, Jacque P. K., Breton-Provencher, Vincent, Knott, Graham W., Okuno, Hiroyuki, Bito, Haruhiko, Sur, Mriganka

“…We found that spike timing–induced receptive field plasticity of visual cortex neurons in mice is anchored by increases in the synaptic strength of identified spines. …”
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Vector-Based Integration of Local and Long-Range Information in Visual Cortex by Somers, David C., Todorov, Emanuel V., Siapas, Athanassios G., Sur, Mriganka

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Spatial Correlations in Natural Scenes Modulate Response Reliability in Mouse Visual Cortex by Rikhye, Rajeev Vijay, Sur, Mriganka

“…Intrinsic neuronal variability significantly limits information encoding in the primary visual cortex (V1). Certain stimuli can suppress this intertrial variability to increase the reliability of neuronal responses. …”
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Cell-specific modulation of plasticity and cortical state by cholinergic inputs to the visual cortex by Sugihara, Hiroki, Chen, Naiyan, Sur, Mriganka

“…Cholinergic neurons from the basal forebrain innervate a wide range of cortical areas, including the primary visual cortex (V1), and multiple cortical cell types have been found to be responsive to ACh. …”
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The influence of astrocytes on the width of orientation hypercolumns in visual cortex: A computational perspective by Philips, Ryan T., Sur, Mriganka, Chakravarthy, V. Srinivasa

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Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation by McCurry, Cortina L., Shepherd, Jason Dennis, Tropea, Daniela, Wang, Kuan H., Bear, Mark, Sur, Mriganka

“…A myriad of mechanisms have been suggested to account for the full richness of visual cortical plasticity. We found that visual cortex lacking Arc is impervious to the effects of deprivation or experience. …”
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Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes by Chen, Naiyan, Sugihara, Hiroki, Sharma, Jitendra, Perea Parrilla, Gertrudis, Petravicz, Jeremy C., Le, Chuong N., Sur, Mriganka

“…Using cell-attached recordings in vivo, we demonstrate that electrical stimulation of the NB, paired with visual stimulation, can induce significant potentiation of visual responses in excitatory neurons of the primary visual cortex in mice. We further show with in vivo two-photon calcium imaging, ex vivo calcium imaging, and whole-cell recordings that this pairing-induced potentiation is mediated by direct cholinergic activation of primary visual cortex astrocytes via muscarinic AChRs. …”
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Functional Biases in Visual Cortex Neurons with Identified Projections to Higher Cortical Targets by Jarosiewicz, Beata, Schummers, James, Malik, Wasim Qamar, Brown, Emery N., Sur, Mriganka

“…These differences could not be explained by a correspondence between anatomical and functional clustering within early visual cortex, and the largest differences were in properties generated within early visual cortex (direction selectivity and length preference) rather than in properties present in its retinogeniculate inputs. …”
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Optogenetic astrocyte activation modulates response selectivity of visual cortex neurons in vivo by Perea, Gertrudis, Yang, Aimei, Sur, Mriganka, Boyden, Edward

“…Here we report that selective photostimulation of astrocytes with channelrhodopsin-2 in primary visual cortex enhances both excitatory and inhibitory synaptic transmission, through the activation of type 1a metabotropic glutamate receptors. …”
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Rapid experience-dependent plasticity of synapse function and structure in ferret visual cortex in vivo by Yu, Hongbo, Majewska, Ania K., Sur, Mriganka

“…To elucidate the relationship between rapid functional changes and dendritic spine remodeling in vivo, we carried out chronic imaging experiments that tracked visual responses and dendritic spines in the ferret visual cortex following brief periods of monocular deprivation. …”
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Response Selectivity Is Correlated to Dendritic Structure in Parvalbumin-Expressing Inhibitory Neurons in Visual Cortex by Runyan, Caroline A., Sur, Mriganka

“…To better understand the distribution and origins of orientation selectivity in inhibitory neurons expressing the calcium binding protein parvalbumin (PV) in the mouse primary visual cortex, we labeled PV[superscript +] neurons with red fluorescent protein (RFP) and targeted them for cell-attached electrophysiological recordings. …”
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miR-132, an experience-dependent microRNA, is essential for visual cortex plasticity by Mellios, Nikolaos, Sugihara, Hiroki, Castro, Jorge, Banerjee, Abhishek, Le, Chuong N., Kumar, Arooshi R., Crawford, Benjamin, Strathmann, Julia, Tropea, Daniela, Edbauer, Dieter, Sur, Mriganka, Levine, Stuart S.

“…Using quantitative analyses, we identified microRNAs (miRNAs) that were abundantly expressed in visual cortex and that responded to dark rearing and/or monocular deprivation. …”
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Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex by Stowell, Rianne D, Sipe, Grayson O, Dawes, Ryan P, Batchelor, Hanna N, Lordy, Katheryn A, Whitelaw, Brendan S, Stoessel, Mark B, Bidlack, Jean M, Brown, Edward, Sur, Mriganka, Majewska, Ania K

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Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex by Stowell, Rianne D., Sipe, Grayson O., Dawes, Ryan P., Batchelor, Hanna N., Lordy, Katheryn A., Whitelaw, Brendan S., Stoessel, Mark B., Bidlack, Jean M., Brown, Edward, Sur, Mriganka, Majewska, Ania K.

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Astrocyte glutamate uptake coordinates experience‐dependent, eye‐specific refinement in developing visual cortex by Sipe, Grayson O., Petravicz, Jeremy, Rikhye, Rajeev V., Garcia, Rodrigo, Mellios, Nikolaos, Sur, Mriganka

“…Here, we examined the structural and functional development of the visual cortex in GLT1 heterozygous (HET) mice using two-photon microscopy, immunohistochemistry and slice electrophysiology. …”
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Experience-dependent regulation of CaMKII activity within single visual cortex synapses in vivo by Mower, Amanda F., Yu, Hongbo, Majewska, Ania K., Okamoto, Ken-Ichi, Hayashi, Yasunori, Sur, Mriganka, Kwok, Show Ming

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Response Features of Parvalbumin-Expressing Interneurons Suggest Precise Roles for Subtypes of Inhibition in Visual Cortex by Runyan, Caroline A., Schummers, James, Van Wart, Audra, Kuhlman, Sandra J., Wilson, Nathan R., Huang, Z. Josh, Sur, Mriganka

“…We used the Cre/LoxP system, specifically labeling parvalbumin(PV)-expressing interneurons in visual cortex of PV-Cre mice with red fluorescent protein (RFP), followed by targeted loose-patch recordings and two-photon imaging of calcium responses in vivo to characterize the visual receptive field properties of these cells. …”
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Reliable Sensory Processing in Mouse Visual Cortex through Cooperative Interactions between Somatostatin and Parvalbumin Interneurons by Rikhye, Rajeev Vijay, Yildirim, Murat, Han, Ming-Hu, Breton-Provencher, Vincent, Sur, Mriganka

“…Intrinsic neuronal variability significantly limits information encoding in the primary visual cortex (V1). However, under certain conditions, neurons can respond reliably with highly precise responses to the same visual stimuli from trial to trial. …”
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Structural Dynamics of Synapses in Vivo Correlate with Functional Changes during Experience-Dependent Plasticity in Visual Cortex by Tropea, Daniela, Majewska, Ania K., Garcia, Rodrigo, Sur, Mriganka

“…We have used optical imaging of mouse visual cortex responses and two-photon imaging of superficial layer spines on layer 5 neurons to monitor network function and synaptic structural dynamics in the mouse visual cortex in vivo. …”
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Functional parcellation of mouse visual cortex using statistical techniques reveals response-dependent clustering of cortical processing areas by Kumar, Mari Ganesh, Hu, Ming, Ramanujan, Aadhirai, Sur, Mriganka, Murthy, Hema A

“…© 2021 Kumar et al. The visual cortex of the mouse brain can be divided into ten or more areas that each contain complete or partial retinotopic maps of the contralateral visual field. …”
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