Virus-like particles of macrobrachium rosenbergii nodavirus capsid as a carrier for immunogenic components by Tan, Wen Siang, Ho, Kok Lian, Yong, Chean Yeah, Goh, Zee Hong, Omar, Abdul Rahman, Yeap, Swee Keong

“…The particles may contain one or more copies of each epitope. The invention further provides a method of producing such VLPs, and uses of such VLPs.…”

Detection of hepatitis B surface antigen by Tan, Wen Siang, Tan, Geok Hun, Mohd Yusoff, Khatijah, Seow, Heng Fong

“…The invention relates to the identification of peptides that interact with hepatitis B surface antigen (HBsAg) and assays for detecting HBsAg in blood samples using the peptides associated with bacteriophages as diagnostic reagents.…”

Recombinant matrix protein of Nipah virus by Tan, Wen Siang, Subramaniam, Senthil Kumar, Tey, Beng Ti, Hamid, Muhajir

“…The present invention provides a recombinant matrix protein of Nipah virus containing matrix protein of nipah virus which includes at least ine His tag and MYC epitope. …”

Nucleotide sequences of the nucleocapsid (NP) gene of a Malaysian velogenic Newcastle disease virus strain AF2240 by Yusoff, Khatijah, Tan, Wen Siang, Kho, Chiew Ling

“…The present invention relates to nucleotide sequences encoding the nucleocapsid (NP) protein and phosphoprotein (P) of Newcastle disease virus (NDV) and the production of the corresponding proteins with recombinant plasmids bearing the nucleotide sequences in Escherichia coli.…”

A method to purify recombinant nucleocapsid protein of Nipah virus using hydrophobic interaction chromatography. by Tey, Beng Ti, Chong, Fui Chin, Tan, Wen Siang

“…The invention provides a method to purify a recombinant virus protein from microbial cells. …”

Hepatitis B core particles with His tags by Tan, Wen Siang, Yap, Wei Boon, Tey, Beng Ti

“…Accordingly, the present invention provides a recombinant fusion protein which includes at least one His tags and hepatitis B virus (HBV)core antigen. …”

Peptides that inhibit the association of the surface and core antigens of hepatitis B virus by Tan, Wen Siang, Seow, Heng Fong, Yusoff, Khatijah, Ho, Kok Lian

“…This invention relates to isolation of high affinity binding phages carrying the fusion peptides which bind specifically to hepatitis B core antigen. …”

Purification of antibodies against hepatitis B. by Ling, Tau Chuan, Wongchupan, Rattana, Tan, Wen Siang, Taip, Farah Saleena

“…The present invention discloses a method for the purification of polyclonal immunoglobin G (IgG) against type B hepatitis infections, the method comprising the steps of: (i) adsorption of serum on diethylaminoethyl (DEAE) sepharose without elution, in which albumin content in the serum is removed: and (ii) adsorption of the albumin depleted serum on an immobilized dye followed by elution, in which the adsorbed antibodies are eluted in pure form. …”

A method for purification of intracellular protein. by Tey, Beng Ti, Chew, Few Ne, Tan, Wen Siang

“…GFP was then separated from other host cells host protein along polyacrylamide gel and finally eluted electrophoretically from the gel. The invention has successfully recovered the GFP with purity and yeild 95% and 82%, respectively in 100 min operation. …”

Peptides that inhibit the propagation of Newcastle disease virus by Tan, Wen Siang, Mohd Yusoff, Khatijah, Nathan, Sheila, Ramanujam, Priadarishini

“…The invention relates to recombinant phages carrying fusion peptides that bind to Newcastle Disease Virus (NDV). …”

Phage display creates innovative applications to combat hepatitis B virus by Tan, Wen Siang, Ho, Kok Lian

“…Hepatitis B virus (HBV) has killed countless lives in human history. The invention of HBV vaccines in the 20th century has reduced significantly the rate of the viral infection. …”
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Loop-mediated isothermal amplification (LAMP) as a promising point-of-care diagnostic strategy in avian virus research by Padzil, Faiz, Abdul Razak, Mariatulqabtiah, Tan, Wen Siang, Ho, Kok Lian, Mat Isa, Nurulfiza, Lau, Han Yih, Abu, Jalila, Chuang, Kuo-Pin

“…While such molecular detection methods are widely utilized as the benchmark, the invention of isothermal amplifications has also emerged as a reliable tool to improvise on-field diagnosis without dependence on thermocyclers. …”