Characterization of kindlin3 in Integrin functions by Feng, Chen

“…Integrins are heterodimeric cell adhesion molecules that are involved in many biological processes. …”
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Talin and kindlin : batman and robin of Mac1 integrin activation? by Henni Djunaidi.

“…Macrophage 1 (Mac1) integrin is a leukocyte-restricted adhesion molecule highly expressed on phagocytes and is essential in the development of immune responses. …”
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Structural and functional characterization of integrin αLβ2 by Tang, Xiaoyan

“…Integrins are adhesion molecules that transmit bidirectional signals across the plasma membrane by undergoing extensive structural changes. …”
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Characterisation of Kindlin-3 and RACK1 interaction in integrin signaling. by Lee, Huishan.

“…Integrins are cell surface receptors which interact with ECM to induce bidirectional signal to mediate cell spreading. …”
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Standing on the shoulders of giant : small membrane molecules that associate laterally with integrins. by Wong, Alvin Yao Sheng.

“…A mode of integrins modulation is lately gaining acceptance and increasingly studied is: how the type of adhesion and signalling following integrins ligation may be modulated by lateral association with other membrane molecules.This review paper will elaborate more on some of these components that interact laterally with integrins and provide modulatory function. …”
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Structure-function analysis of ß2 integrins using monoclonal antibodies. by Foo, Adeline Shen Yun.

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Investigating integrin αMβ2 outside-in signaling in human monocytes by Xue, Zhihong

“…Integrins are type I transmembrane and α/β heterodimeric adhesion receptors that mediate the interaction of cells and the extracellular matrix (ECM) or adjacent cells. …”
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Investigating the roles of cytoplasmic proteins talin and kindlin3 in integrin LFA-1 activation by Li, Yan Feng

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Investigating the interaction between integrin αL cytoplasmic domain and CD45 full-length cytoplasmic domain. by Quek, Ardy Rui Ming.

“…The cell adhesion molecule integrin αLβ2 and the phosphatase CD45 are important molecules in maintaining a functional immune system. …”
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Mechanistic insights into kindlin function and regulation by Levitskaya, Zarina

“…Kindlins are FERM domain containing adapter proteins known for their role in integrin inside-out and outside-in activation and signalling. …”
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Functional characterization of αMβ2-uPar interaction by Tang, Manli

“…The cell adhesion molecule integrin αMβ2, one of the β2 integrins, associates with the urokinase-type plasminogen activator receptor (uPAR) on monocytes and neutrophils. …”
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Investigating the functions of alternatively spliced Kindlin-2 by Wong, Jun Sheng

“…Kindlins are cytoplasmic proteins that function as an important co-activator for integrin activation. They are important for cell adhesion and migration. …”
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Investigating the functions and signaling properties of kindlins by Tan, Hui Foon

“…The primary role of kindlins is to regulate the activity of integrins by binding directly to β integrin cytoplasmic tails. …”
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Investigating the role of kindlin-3 in protein translation and tumorigenesis via interaction with RACK1 by Qu, Jing

“…Kindlins modulate cell-cell and cell-Extracellular Matrix (ECM) interaction by regulating the ligand-binding affinity and avidity of the cell surface adhesion molecules-integrins. Kindlin-3 stabilizes β1, β2 and β3 integrins-mediated cell adhesion. …”
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