Glaucoma and microglia-induced neuroinflammation by Makoto Ishikawa, Makoto Ishikawa, Yukitoshi Izumi, Yukitoshi Izumi, Yukitoshi Izumi, Kota Sato, Kota Sato, Taimu Sato, Charles F. Zorumski, Charles F. Zorumski, Charles F. Zorumski, Hiroshi Kunikata, Hiroshi Kunikata, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa

Subjects: “…glaucoma…”
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Corrigendum: Glaucoma and microglia-induced neuroinflammation by Makoto Ishikawa, Makoto Ishikawa, Yukitoshi Izumi, Yukitoshi Izumi, Yukitoshi Izumi, Kota Sato, Kota Sato, Taimu Sato, Charles F. Zorumski, Charles F. Zorumski, Charles F. Zorumski, Hiroshi Kunikata, Hiroshi Kunikata, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa, Toru Nakazawa

Subjects: “…glaucoma…”
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Clinical characteristics of glaucoma patients with various risk factors by Kazuko Omodaka, Tsutomu Kikawa, Sayaka Kabakura, Noriko Himori, Satoru Tsuda, Takahiro Ninomiya, Naoki Takahashi, Kyongsun Pak, Noriyasu Takeda, Masahiro Akiba, Toru Nakazawa

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Genetic variants associated with glaucomatous visual field loss in primary open-angle glaucoma by Fumihiko Mabuchi, Nakako Mabuchi, Yoichi Sakurada, Seigo Yoneyama, Kenji Kashiwagi, Zentaro Yamagata, Mitsuko Takamoto, Makoto Aihara, Takeshi Iwata, Kazuki Hashimoto, Kota Sato, Yukihiro Shiga, Toru Nakazawa, Masato Akiyama, Kazuhide Kawase, Mineo Ozaki, Makoto Araie

“…Abstract Primary open-angle glaucoma (POAG) is characterized by a progressive optic neuropathy with visual field loss. …”
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A quality management system aiming to ensure regulatory-grade data quality in a glaucoma registry. by Shinsuke Wada, Satoru Tsuda, Maiko Abe, Toru Nakazawa, Hisashi Urushihara

“…<h4>Conclusions</h4>We established and configured a quality management system for a glaucoma registry to ensure fit-for-purpose data quality for regulatory use, and to curate long-term follow-up data of glaucoma patients in a prospective manner.…”
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METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma by Yang Pan, Akiko Suga, Itaru Kimura, Chojiro Kimura, Yuriko Minegishi, Mao Nakayama, Kazutoshi Yoshitake, Daisuke Iejima, Naoko Minematsu, Megumi Yamamoto, Fumihiko Mabuchi, Mitsuko Takamoto, Yukihiro Shiga, Makoto Araie, Kenji Kashiwagi, Makoto Aihara, Toru Nakazawa, Takeshi Iwata

“…Normal-tension glaucoma (NTG) is a heterogeneous disease characterized by retinal ganglion cell (RGC) death leading to cupping of the optic nerve head and visual field loss at normal intraocular pressure (IOP). …”
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Vasoreactivity of the optic nerve head, nailfold, and facial skin in response to cold provocation in normal-tension glaucoma patients by Nana Takahashi, Naoki Kiyota, Hiroshi Kunikata, Mai Yamazaki, Takayuki Nishimura, Yukihiro Shiga, Hisae Aoyagi, Miwako Shidomi, Tomohiro Tsuda, Toshihiko Ohtsuka, Takahiro Tomida, Toru Nakazawa

“…Abstract Background The dysfunction of optic nerve head (ONH) hemodynamics has been suggested to be involved in the pathogenesis of normal-tension glaucoma (NTG). The aim of this study was to compare vasoreactivity in the ONH, nailfold, and facial skin in response to cold-water provocation in NTG patients and healthy controls. …”
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Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…Background/aims This study aimed to investigate and compare the efficacy and safety of first-line and second-line selective laser trabeculoplasty (SLT) in Japanese patients with normal-tension glaucoma (NTG).Methods 100 patients with NTG were enrolled in this study. …”
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Sex differences in the association between systemic oxidative stress status and optic nerve head blood flow in normal-tension glaucoma by Masataka Sato, Masayuki Yasuda, Nana Takahashi, Kazuki Hashimoto, Noriko Himori, Toru Nakazawa

“…<h4>Purpose</h4> To investigate the association of systemic oxidative stress markers and optic nerve head (ONH) blood flow in normal-tension glaucoma (NTG) patients, as well as sex differences in this association. …”
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Sex differences in the association between systemic oxidative stress status and optic nerve head blood flow in normal-tension glaucoma. by Masataka Sato, Masayuki Yasuda, Nana Takahashi, Kazuki Hashimoto, Noriko Himori, Toru Nakazawa

“…<h4>Purpose</h4>To investigate the association of systemic oxidative stress markers and optic nerve head (ONH) blood flow in normal-tension glaucoma (NTG) patients, as well as sex differences in this association.…”
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Predictive potential of optical coherence tomography parameters for the prognosis of decreased visual acuity after trabeculectomy in open-angle glaucoma patients with good vision by Yoko Takeda, Naoki Takahashi, Naoki Kiyota, Taiki Kokubun, Satoru Tsuda, Kazuko Omodaka, Yu Yokoyama, Toru Nakazawa

“…Abstract Background Trabeculectomy (trab) is the most effective surgical procedure for lowering IOP and preventing glaucoma progression. However, decline in best-corrected visual acuity (BCVA) is one of the most serious postoperative complications of trab. …”
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Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7. by Yukihiro Shiga, Koji M Nishiguchi, Yosuke Kawai, Kaname Kojima, Kota Sato, Kosuke Fujita, Mai Takahashi, Kazuko Omodaka, Makoto Araie, Kenji Kashiwagi, Makoto Aihara, Takeshi Iwata, Fumihiko Mabuchi, Mitsuko Takamoto, Mineo Ozaki, Kazuhide Kawase, Nobuo Fuse, Masayuki Yamamoto, Jun Yasuda, Masao Nagasaki, Toru Nakazawa, Japan Glaucoma Society Omics Group (JGS-OG)

“…To test the genetic association between Japanese patients with primary open-angle glaucoma (POAG) and the previously reported POAG susceptibility loci and to perform genotype-phenotype analysis.Genetic associations for 27 SNPs from 16 loci previously linked to POAG were assessed using genome-wide SNP data of the primary cohort (565 Japanese POAG patients and 1,104 controls). …”
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Neurosteroids as stress modulators and neurotherapeutics: lessons from the retina by Yukitoshi Izumi, Makoto Ishikawa, Toru Nakazawa, Hiroshi Kunikata, Kota Sato, Douglas F Covey, Charles F Zorumski

Subjects: “…allopregnanolone; autophagy; enantiomers; excitotoxicity; gamma-aminobutyric acid type a receptors; glaucoma; optic nerve; oxysterols…”
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Comparing Trabeculectomy Outcomes between First and Second Operated Eyes: A Multicenter Study. by Kentaro Iwasaki, Yoshihiro Takamura, Takashi Nishida, Akira Sawada, Keiichiro Iwao, Ayano Shinmura, Shiho Kunimatsu-Sanuki, Tetsuya Yamamoto, Hidenobu Tanihara, Kazuhisa Sugiyama, Toru Nakazawa, Masaru Inatani

“…METHODS:This retrospective clinical cohort study at five clinical centers in Japan included 84 patients with open-angle glaucoma who underwent primary trabeculectomy in both eyes. …”
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A ginger extract improves ocular blood flow in rats with endothelin-induced retinal blood flow dysfunction by Nana Takahashi, Kota Sato, Naoki Kiyota, Satoru Tsuda, Namie Murayama, Toru Nakazawa

“…This suggests that our newly developed supplement for improving ONH BF has a potential role in retinal ischemic diseases, including glaucoma.…”
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