Serum vitamin D and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). by Travis, R, Crowe, F, Allen, N, Appleby, P, Roddam, A, Tjønneland, A, Olsen, A, Linseisen, J, Kaaks, R, Boeing, H, Kröger, J, Trichopoulou, A, Dilis, V, Trichopoulos, D, Vineis, P, Palli, D, Tumino, R, Sieri, S, Bueno-de-Mesquita, H, van Duijnhoven, F, Chirlaque, MD, Barricarte, A, Larrañaga, N, González, C, Argüelles, M, Sánchez, M, Stattin, P, Hallmans, G, Khaw, K, Bingham, S, Rinaldi, S, Slimani, N, Jenab, M, Riboli, E, Key, T

“…The authors examined whether vitamin D concentrations were associated with prostate cancer risk in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (1994-2000). …”

Serum vitamin d and risk of prostate cancer in a case-control analysis nested within the european prospective investigation into cancer and nutrition (EPIC) by Travis, R, Crowe, F, Allen, N, Appleby, P, Roddam, A, Tjønneland, A, Olsen, A, Linseisen, J, Kaaks, R, Boeing, H, Kröger, J, Trichopoulou, A, Dilis, V, Trichopoulos, D, Vineis, P, Palli, D, Tumino, R, Sieri, S, Bueno-De-Mesquita, H, Van Duijnhoven, F, Chirlaque, M, Barricarte, A, Larrañaga, N, González, C, Argüelles, M

“…The authors examined whether vitamin D concentrations were associated with prostate cancer risk in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (1994-2000). …”

A nested case-control study of metabolically defined body size phenotypes and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) by Murphy, N, Cross, A, Abubakar, M, Jenab, M, Aleksandrova, K, Boutron-Ruault, M, Dossus, L, Racine, A, Kühn, T, Katzke, V, Tjønneland, A, Petersen, K, Overvad, K, Quirós, JR, Jakszyn, P, Molina-Montes, E, Dorronsoro, M, Huerta, J, Barricarte, A, Khaw, K, Wareham, N, Travis, R, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Masala, G, Krogh, V, Tumino, R, Vineis, P, Panico, S, Bueno-de-Mesquita, H, Siersema, P, Peeters, P, Ohlsson, B, Ericson, U, Palmqvist, R, Nyström, H, Weiderpass, E, Skeie, G, Freisling, H, Kong, S, Tsilidis, K, Muller, D, Riboli, E, Gunter, M

“…Whether similarly variable relationships exist for metabolically defined body size phenotypes and colorectal cancer risk is unknown.The association of metabolically defined body size phenotypes with colorectal cancer was investigated in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) study. …”

A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and Nutrition. by Casabonne, D, Michael, K, Waterboer, T, Pawlita, M, Forslund, O, Burk, R, Travis, R, Key, T, Newton, R

“…In a prospective pilot study nested in the EPIC-Oxford cohort, we examined the seroprevalence of antibodies against the L1 antigen of 38 human papilloma virus (HPV) types among 39 cases of cutaneous squamous cell carcinoma (SCC) for whom plasma was collected prior to diagnosis (incident) and 80 controls. …”

Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition. by Travis, R, Key, T, Allen, N, Appleby, P, Roddam, A, Rinaldi, S, Egevad, L, Gann, P, Rohrmann, S, Linseisen, J, Pischon, T, Boeing, H, Johnsen, N, Tjønneland, A, Overvad, K, Kiemeney, L, Bueno-de-Mesquita, H, Bingham, S, Khaw, K, Tumino, R, Sieri, S, Vineis, P, Palli, D, Quirós, JR, Ardanaz, E

“…We examined the hypothesis that serum concentrations of circulating androgens and sex hormone binding globulin (SHBG) are associated with risk for prostate cancer in a case-control study nested in the European Prospective Investigation into Cancer and Nutrition (EPIC). …”

Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: Results from the European prospective investigation into cancer and nutr... by Allen, N, Key, T, Appleby, P, Travis, R, Roddam, A, Rinaldi, S, Egevad, L, Rohrmann, S, Linseisen, J, Pischon, T, Boeing, H, Johnsen, N, Tjonneland, A, Gronbaek, H, Overvad, K, Kiemeney, L, Bueno-de-Mesquita, H, Bingham, S, Khaw, K, Tumino, R, Berrino, F, Mattiello, A, Sacerdote, C, Palli, D, Quiros, JR

“…Methods: We analyzed the association between prediagnostic serum concentrations of IGF-I and IGF-binding protein-3 (IGFBP-3) and prostate cancer risk in a case-control study nested in the European Prospective Investigation into Cancer and Nutrition. …”

Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutr... by Allen, N, Key, T, Appleby, P, Travis, R, Roddam, A, Rinaldi, S, Egevad, L, Rohrmann, S, Linseisen, J, Pischon, T, Boeing, H, Johnsen, N, Tjønneland, A, Grønbaek, H, Overvad, K, Kiemeney, L, Bueno-de-Mesquita, H, Bingham, S, Khaw, K, Tumino, R, Berrino, F, Mattiello, A, Sacerdote, C, Palli, D, Quirós, JR

“…METHODS: We analyzed the association between prediagnostic serum concentrations of IGF-I and IGF-binding protein-3 (IGFBP-3) and prostate cancer risk in a case-control study nested in the European Prospective Investigation into Cancer and Nutrition. …”

Genetic variation in the lactase gene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition by Travis, R, Appleby, P, Siddiq, A, Allen, N, Kaaks, R, Canzian, F, Feller, S, Tjønneland, A, Føns Johnsen, N, Overvad, K, Ramõn Quirõs, J, González, C, Sánchez, M, Larrañaga, N, Chirlaque, M, Barricarte, A, Khaw, K, Wareham, N, Trichopoulou, A, Valanou, E, Oustoglou, E, Palli, D, Sieri, S, Tumino, R, Sacerdote, C

“…The current study was nested in EPIC, and results from this first Europe-wide study suggest that while the C/T13910 lactase polymorphism is associated with milk intake, the variant has no large effect on prostate cancer risk. …”

Prediagnostic concentrations of plasma genistein and prostate cancer risk in 1,605 men with prostate cancer and 1,697 matched control participants in EPIC. by Travis, R, Allen, N, Appleby, P, Price, A, Kaaks, R, Chang-Claude, J, Boeing, H, Aleksandrova, K, Tjønneland, A, Johnsen, N, Overvad, K, Ramón Quirós, J, González, C, Molina-Montes, E, Sánchez, M, Larrañaga, N, Castaño, J, Ardanaz, E, Khaw, K, Wareham, N, Trichopoulou, A, Karapetyan, T, Rafnsson, S, Palli, D, Krogh, V

“…We examined the association between circulating concentrations of genistein and prostate cancer risk in a case-control study nested in the European Prospective Investigation into Cancer and Nutrition. …”

Variation in genes coding for AMP-activated protein kinase (AMPK) and breast cancer risk in the European Prospective Investigation on Cancer (EPIC). by Campa, D, Claus, R, Dostal, L, Stein, A, Chang-Claude, J, Meidtner, K, Boeing, H, Olsen, A, Tjønneland, A, Overvad, K, Rodríguez, L, Bonet, C, Sánchez, M, Amiano, P, Huerta, J, Barricarte, A, Khaw, K, Wareham, N, Travis, R, Allen, N, Trichopoulou, A, Bamia, C, Benetou, V, Palli, D, Agnoli, C

“…We tested association of tagging SNPs in our four candidate genes with breast cancer (BC) risk in a study of 1340 BC cases and 2536 controls nested into the European Prospective Investigation into Cancer and Nutrition (EPIC). …”

Genetic variability of the forkhead box O3 and prostate cancer risk in the European Prospective Investigation on Cancer. by Campa, D, Hüsing, A, Dostal, L, Stein, A, Drogan, D, Boeing, H, Tjønneland, A, Roswall, N, Østergaard, J, Overvad, K, Rodríguez, L, Bonet, C, Sánchez, M, Larrañaga, N, Huerta, J, Ardanaz, E, Khaw, K, Wareham, N, Travis, R, Allen, N, Trichopoulou, A, Zylis, D, Karapetyan, T, Palli, D, Sieri, S

“…Three SNPs in the FOXO3 gene (rs3800231, rs9400239 and rs479744) that have been shown to be strongly and consistently associated with longevity, were examined in relation to PC risk in a case control study of 1571 incident PC cases and 1840 controls nested within the European Prospective Investigation into Cancer and Nutrition (EPIC). …”

Investigating sources of variability in metabolomic data in the EPIC study: the Principal Component Partial R-square (PC-PR2) method by Fages, A, Ferrari, P, Monni, S, Dossus, L, Floegel, A, Mode, N, Johansson, M, Travis, R, Bamia, C, Sanchez-Perez, M, Chiodini, P, Boshuizen, H, Chadeau-Hyam, M, Riboli, E, Jenab, M, Elena-Herrmann, B

“…Within the European Prospective Investigation into Cancer and nutrition (EPIC), metabolic profiles were determined by 1H NMR analysis on 807 serum samples originating from a nested liver cancer case-control study. PC-PR2 was used to quantify the variability of metabolomic profiles in terms of study subjects age, sex, body mass index, country of origin, smoking status, diabetes and fasting status, as well as factors related to sample processing. …”

Plasma phyto-oestrogens and prostate cancer in the European Prospective Investigation into Cancer and Nutrition. by Travis, R, Spencer, E, Allen, N, Appleby, P, Roddam, A, Overvad, K, Johnsen, N, Olsen, A, Kaaks, R, Linseisen, J, Boeing, H, Nöthlings, U, Bueno-de-Mesquita, H, Ros, M, Sacerdote, C, Palli, D, Tumino, R, Berrino, F, Trichopoulou, A, Dilis, V, Trichopoulos, D, Chirlaque, MD, Ardanaz, E, Larranaga, N, Gonzalez, C

“…We examined plasma concentrations of phyto-oestrogens in relation to risk for subsequent prostate cancer in a case-control study nested in the European Prospective Investigation into Cancer and Nutrition. …”

First-morning urinary melatonin and breast cancer risk in the guernsey study by Wang, X, Tipper, S, Appleby, P, Allen, N, Key, T, Travis, R

“…We examined the association between nocturnal melatonin and breast cancer risk in a case-control study nested within the Guernsey III Study, a British prospective cohort study (1977-2009). …”

Menstrual and reproductive factors in women, genetic variation in CYP17A1, and pancreatic cancer risk in the European prospective investigation into cancer and nutrition (EPIC) coh... by Duell, E, Travier, N, Lujan-Barroso, L, Dossus, L, Boutron-Ruault, M, Clavel-Chapelon, F, Tumino, R, Masala, G, Krogh, V, Panico, S, Ricceri, F, Redondo, M, Dorronsoro, M, Molina-Montes, E, Huerta, J, Barricarte, A, Khaw, K, Wareham, N, Allen, N, Travis, R, Siersema, P, Peeters, P, Trichopoulou, A, Fragogeorgi, E, Oikonomou, E

“…Then, in a case-control study nested within the EPIC cohort, we examined 12 single nucleotide polymorphisms (SNPs) in CYP17A1 (an essential gene in sex steroid metabolism) for association with pancreatic cancer in women and men (324 cases and 353 controls). …”

First-morning urinary melatonin and breast cancer risk in the Guernsey Study. by Wang, X, Tipper, S, Appleby, P, Allen, N, Key, T, Travis, R

“…We examined the association between nocturnal melatonin and breast cancer risk in a case-control study nested within the Guernsey III Study, a British prospective cohort study (1977-2009). …”

Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition by Perez-Cornago, A, Appleby, P, Tipper, S, Key, T, Allen, N, Nieters, A, Vermeulen, R, Roulland, S, Casabonne, D, Kaaks, R, Fortner, R, Boeing, H, Trichopoulou, A, La Vecchia, C, Klinaki, E, Hansen, L, Tjønneland, A, Bonnet, F, Fagherazzi, G, Boutron-Ruault, M, Pala, V, Masala, G, Sacerdote, C, Peeters, P, Bueno-de-Mesquita, H, Weiderpass, E, Dorronsoro, M, Quirós, J, Barricarte, A, Gavrila, D, Agudo, A, Borgquist, S, Rosendahl, A, Melin, B, Wareham, N, Khaw, K, Gunter, M, Riboli, E, Vineis, P, Travis, R

“…IGF-I concentration was measured in pre-diagnostic plasma samples from a nested case-control study of 1072 cases of lymphoid malignancies and 1072 individually matched controls from the European Prospective Investigation into Cancer and Nutrition. …”

The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk by Campa, D, Hüsing, A, McKay, J, Sinilnikova, O, Vogel, U, Tjønneland, A, Overvad, K, Stegger, J, Clavel-Chapelon, F, Chabbert-Buffet, N, Fagherazzi, G, Trichopoulou, A, Zylis, D, Oustoglou, E, Rohrmann, S, Teucher, B, Fisher, E, Boeing, H, Masala, G, Krogh, V, Sacerdote, C, Panico, S, Tumino, R, Onland-Moret, N, Gils, V, Bueno-De-Mesquita, H, Lund, E, Chirlaque, MD, Sala, N, Quirós, JR, Ardanaz, E, Amiano, P, Molina-Montes, E, Hallmans, G, Lenner, P, Travis, R, Key, T, Wareham, N, Khaw, K, Rinaldi, S, Slimani, N, Chajes, V, Siddiq, A, Riboli, E, Kaaks, R, Canzian, F

“…<br/><br/> <b>Methods:</b> we tested in a large-scale association study (3,973 women, including 1,269 invasive BC cases and 2,194 controls), nested within the EPIC cohort, the involvement of rs7566605 as predictor of BMI and BC risk.…”

Physical activity, sex steroid, and growth factor concentrations in pre- and post-menopausal women: A cross-sectional study within the EPIC cohort by Rinaldi, S, Kaaks, R, Friedenreich, C, Key, T, Travis, R, Biessy, C, Slimani, N, Overvad, K, Østergaard, J, Tjønneland, A, Olsen, A, Mesrine, S, Fournier, A, Dossus, L, Lukanova, A, Johnson, T, Boeing, H, Vigl, M, Trichopoulou, A, Benetou, V, Trichopoulos, D, Masala, G, Krogh, V, Tumino, R, Ricceri, F

“…Methods: A cross-sectional analysis of 798 pre- and 1,360 post-menopausal women included as controls in case-control studies on endogenous hormones (steroids, progesterone, sex-hormone-binding globulin (SHBG), and growth factors) levels, and cancer risk nested within European Prospective Investigation into Cancer and Nutrition cohort was performed. …”

Androgens are differentially associated with ovarian cancer subtypes in the Ovarian Cancer Cohort Consortium by Ose, J, Poole, E, Schock, H, Lehtinen, M, Arslan, A, Zeleniuch-Jacquotte, A, Visvanathan, K, Helzlsouer, K, Buring, J, Lee, I, Tjønneland, A, Dossus, L, Trichopoulou, A, Masala, G, Onland-Moret, N, Weiderpass, E, Duell, E, Idahl, A, Travis, R, Rinaldi, S, Merritt, M, Trabert, B, Wentzensen, N, Tworoger, S, Kaaks, R, Fortner, R

“…We conducted a pooled analysis of 7 nested case-control studies in the Ovarian Cancer Cohort Consortium to investigate the association between pre-diagnosis circulating androgens (testosterone, free testosterone, androstenedione, dehydroepiandrosterone sulfate (DHEAS)), sex hormone binding globulin (SHBG), and EOC risk by tumor characteristics (i.e. histology, grade, and stage). …”