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    Individuals With Weaker Antibody Responses After Booster Immunization Are Prone to Omicron Breakthrough Infections by Birte Möhlendick, Ieva Čiučiulkaitė, Carina Elsner, Olympia E. Anastasiou, Mirko Trilling, Bernd Wagner, Denise Zwanziger, Karl-Heinz Jöckel, Ulf Dittmer, Winfried Siffert

    Published 2022-06-01
    “…Until now, there is no information whether a potential risk of a breakthrough infection can be inferred from the level of antibodies after booster vaccination.MethodsLevels of binding antibodies and neutralization capacity after the first, one and six month after the second, and one month after the third (booster) vaccination against COVID-19 were measured in serum samples from 1391 healthcare workers at the University Hospital Essen. Demographics, vaccination scheme, pre-infection antibody titers and neutralization capacity were compared between individuals with and without breakthrough infections.ResultsThe risk of developing an Omicron breakthrough infection was independent of vaccination scheme, sex, body mass index, smoking status or pre-existing conditions. …”
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