Work related symptoms, sensitisation, and estimated exposure in workers not previously exposed to flour. by Cullinan, P, Lowson, D, Nieuwenhuijsen, M, Sandiford, C, Tee, R, Venables, K, McDonald, J, Newman Taylor, A

“…The relations with eye/nose and skin symptoms were independent of atopic status and cigarette smoking. Positive skin test responses to mixed flour and to alpha amylase were also more frequent with increasing exposure intensity, although this was confounded by atopic status. …”

Acid anhydrides and asthma. by Taylor, A, Venables, K, Durham, SR, Graneek, B, Topping, MD

“…Survey of the factory population where these 7 cases worked allowed investigation of the determinants of the specific IgE response: its presence was associated with intensity of exposure and current cigarette smoking; in addition smoking interacted with atopy to increase the prevalence of specific IgE. …”

Allergen exposure, atopy and smoking as determinants of allergy to rats in a cohort of laboratory employees. by Cullinan, P, Cook, A, Gordon, S, Nieuwenhuijsen, M, Tee, R, Venables, K, McDonald, J, Taylor, A

“…Atopy increased the OR of most outcomes as did cigarette smoking, although there was no evidence of a relationship between smoking and the development of a specific skin test reaction. …”

Risk factors for sensitisation and respiratory symptoms among workers exposed to acid anhydrides: a cohort study. by Barker, R, van Tongeren, M, Harris, J, Gardiner, K, Venables, K, Newman Taylor, A

“…CONCLUSIONS: Intensity of exposure and cigarette smoking may be risk factors for sensitisation to acid anhydrides. …”

Allergen and dust exposure as determinants of work-related symptoms and sensitization in a cohort of flour-exposed workers; a case-control analysis. by Cullinan, P, Cook, A, Nieuwenhuijsen, M, Sandiford, C, Tee, R, Venables, K, McDonald, J, Newman Taylor, A

“…These findings were unaffected by age, sex or cigarette smoking. CONCLUSIONS: In this population, many work-related symptoms which develop after first employment in modern UK bakeries or flour mills were not accompanied by evidence of IgE sensitization to flour or alpha-amylase. …”

Smoking and occupational allergy in workers in a platinum refinery. by Venables, K, Dally, M, Nunn, A, Stevens, J, Stephens, R, Farrer, N, Hunter, J, Stewart, M, Hughes, E, Newman Taylor, A

“…Smoking was the only significant predictor of a positive result on skin testing with platinum salts and its effect was greater than that of atopy; the estimated relative risks (95% confidence interval) when both were included in the regression model were: smokers versus non-smokers 5.05 (1.68 to 15.2) and atopic versus non-atopic 2.29 (0.88 to 5.99). Number of cigarettes smoked per day was the only significant predictor of respiratory symptoms. …”