Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential by Minlan Yuan, Biao Yang, Gerson Rothschild, J. John Mann, Larry D. Sanford, Xiangdong Tang, Canhua Huang, Chuang Wang, Wei Zhang

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MiRNA-mRNA integrative analysis reveals epigenetically regulated and prognostic miR-103a with a role in migration and invasion of carboplatin-resistant ovarian cancer cells that acquired mesenchymal-like phenotype by Margareta Pernar Kovač, Vanja Tadić, Juran Kralj, Marija Milković Periša, Slavko Orešković, Ivan Babić, Vladimir Banović, Wei Zhang, Zoran Culig, Anamaria Brozovic

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Enhanced CXCR4 Expression Associates with Increased Gene Body 5-Hydroxymethylcytosine Modification but not Decreased Promoter Methylation in Colorectal Cancer by Alexei J. Stuckel, Wei Zhang, Xu Zhang, Shuai Zeng, Urszula Dougherty, Reba Mustafi, Qiong Zhang, Elsa Perreand, Tripti Khare, Trupti Joshi, Diana C. West-Szymanski, Marc Bissonnette, Sharad Khare

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Epigenetic DNA Modifications Upregulate SPRY2 in Human Colorectal Cancers by Alexei J. Stuckel, Shuai Zeng, Zhen Lyu, Wei Zhang, Xu Zhang, Urszula Dougherty, Reba Mustafi, Qiong Zhang, Trupti Joshi, Marc Bissonnette, Samrat Roy Choudhury, Sharad Khare

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SETD2 deficiency promotes renal fibrosis through the TGF‐β/Smad signalling pathway in the absence of VHL by Changwei Liu, Li Ni, Xiaoxue Li, Hanyu Rao, Wenxin Feng, Yiwen Zhu, Wei Zhang, Chunxiao Ma, Yue Xu, Liming Gui, Ziyi Wang, Rebiguli Aji, Jin Xu, Wei‐Qiang Gao, Li Li

Subjects: “…epigenetic regulation…”
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LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation by Lihui Liu, Ziyang Liu, Qinghua Liu, Wei Wu, Peng Lin, Xing Liu, Yuechuan Zhang, Dongpeng Wang, Briana C. Prager, Ryan C. Gimple, Jichuan Yu, Weixi Zhao, Qiulian Wu, Wei Zhang, Erzhong Wu, Xiaomin Chen, Jianjun Luo, Jeremy N. Rich, Qi Xie, Tao Jiang, Runsheng Chen

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An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4. by Ke Ren, Wei Zhang, Xiaoqing Chen, Yingyu Ma, Yue Dai, Yimei Fan, Yayi Hou, Ren Xiang Tan, Erguang Li

“…By screening a chemical library of epigenetic regulation, we identified bromodomain-containing protein 4 (BRD4) as a critical player in HSV infection. …”
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LDHA: The Obstacle to T cell responses against tumor by Yu Tang, Shuangshuang Gu, Liqun Zhu, Yujiao Wu, Wei Zhang, Chuanxiang Zhao

“…Furthermore, we have discussed the various aspects of epigenetic regulation of LDHA expression, such as histone modification, DNA methylation, N6-methyladenosine (m6A) RNA methylation, and transcriptional control by noncoding RNA. …”
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The characteristics of extrachromosomal circular DNA in patients with end-stage renal disease by Yue Peng, Yixi Li, Wei Zhang, Yu ShangGuan, Ting Xie, Kang Wang, Jing Qiu, Wenjun Pu, Biying Hu, Xinzhou Zhang, Lianghong Yin, Donge Tang, Yong Dai

“…In addition to the structurally intact chromosome genomic DNA, there is a double-stranded circular DNA called extrachromosomal circular DNA (eccDNA), which is thought to be involved in the epigenetic regulation of human disease. However, the features of eccDNA in ESRD patients are barely known. …”
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Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation. by Hong Zhou, Yapei Wang, Qiongying Lv, Juan Zhang, Qing Wang, Fei Gao, Haoli Hou, Hao Zhang, Wei Zhang, Lijia Li

“…Aberrant expression of the rRNA gene has been generally observed in tumor cells and levels of its promoter methylation as an epigenetic regulator affect rRNA gene transcription. The possible relationship between expression and promoter methylation of rDNA has not been examined in human clinical cervical cancer. …”
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