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TOGA Therapeutic Oxygen for Gastrointestinal Atony
Published 2024-01-01“…Conclusion: In this first clinical report of therapeutic oxygen for gastrointestinal atony, the provision of 100% oxygen via nonrebreather mask is a useful therapy. …”
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An aptamer-based depot system for sustained release of small molecule therapeutics
Published 2023-04-01“…Abstract Delivery of hydrophilic small molecule therapeutics by traditional drug delivery systems is challenging. …”
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Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors
Published 2021-06-01“…In this review, we will provide a thorough overview of small-molecule UPS inhibitors and highlight advancements in the development of targeted protein degradation strategies for cancer therapeutics.…”
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Herbal medicine derived carbon dots: synthesis and applications in therapeutics, bioimaging and sensing
Published 2021-10-01“…In terms of the applications of HM-CDs, medical therapeutics, ion and molecular detection, bioimaging, as well as pH sensing are summarized. …”
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Targeting Inflammasome Activation in Viral Infection: A Therapeutic Solution?
Published 2023-06-01“…We also discuss the current achievement of the mechanisms involved in viral infection-induced inflammatory response, host defense, and possible therapeutic solutions.…”
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Non-coding RNAs are key players and promising therapeutic targets in atherosclerosis
Published 2023-09-01“…Here, we review the role of ncRNAs in AS development and recent developments in the use of ncRNAs for AS-targeted therapy, providing evidence for ncRNAs as diagnostic markers and therapeutic targets.…”
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Graphene-based nanomaterials for stimuli-sensitive controlled delivery of therapeutic molecules
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Prostaglandin Reductase 1 as a Potential Therapeutic Target for Cancer Therapy
Published 2021-08-01Subjects: Get full text
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Osteoblastic microRNAs in skeletal diseases: Biological functions and therapeutic implications
Published 2022-09-01“…Our summary provides novel horizon for improving the therapeutic effect of microRNAs, which may be beneficial to the further clinical translation of microRNAs in the treatments of skeletal diseases.…”
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Corrigendum: Prostaglandin reductase 1 as a potential therapeutic target for cancer therapy
Published 2023-05-01Subjects: Get full text
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The therapeutic and prognostic role of cuproptosis-related genes in triple negative breast cancer
Published 2023-05-01“…Abstract Background This study aimed to observe the potential impact of known cuproptosis-related genes (CRGs) on triple negative breast cancer (TNBC) development, as well as their associated molecular mechanisms, immune infiltration mechanisms and potential therapeutic agents. Results Based on the Cox Proportional Hazard Model, 11 CRGs may be especially important in TNBC development and progression (considered as the Key-TNBC-CRGs). …”
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The potential of Panax notoginseng against COVID-19 infection
Published 2023-09-01Subjects: Get full text
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Silk fibroin-based embolic agent for transhepatic artery embolization with multiple therapeutic potentials
Published 2023-08-01“…The whole procedure of selective internal radiation was recorded with SPECT/CT, and the therapeutic effects were evaluated with 18 F-FDG PET/CT. …”
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Combining the Anticancer and Immunomodulatory Effects of <i>Astragalus</i> and Shiitake as an Integrated Therapeutic Approach
Published 2021-07-01“…Notably, our data suggest that this new manufacturing process can result in transfer and increased bioavailability of <i>Astragalus</i> polysaccharides with therapeutic potential into edible Shiitake. Further research efforts are required to validate the therapeutic potential of this new Hengshan <i>Astragalus</i> Shiitake medicinal food.…”
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In Vitro Validation of the Therapeutic Potential of Dendrimer-Based Nanoformulations against Tumor Stem Cells
Published 2022-05-01Subjects: Get full text
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The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage
Published 2023-01-01“…Even there is no clear and effective therapeutic strategy for SAH thus far, but by understanding apoptosis, we might excavate new ideas and approaches, as targeting the upstream and downstream molecules of apoptosis-related pathways shows promise in the treatment of SAH. …”
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Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody
Published 2018-02-01“…These findings suggest a novel therapeutic strategy for ALS, using an antibody format with clinical precedence, which targets a pathway essential for maintaining attachment of nerve terminals to muscle.…”
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From iron chelation to overload as a therapeutic strategy to induce ferroptosis in hematologic malignancies
Published 2022-12-01“…This review elaborates the regulatory mechanism of ferroptosis and the treatment opportunities for targeting ferroptosis in hematologic malignancies.Methods: A systematic literature review through PubMed was conducted to summarize the published evidence on the therapeutic potential of targeting ferroptosis in hematological malignant tumors. …”
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Therapeutic effect of Bacillus Calmette–Guerin polysaccharide nucleic acid on mast cell at the transcriptional level
Published 2019-08-01Subjects: Get full text
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