Complex visual hallucinations in partial blindness due to eye disease. by White, N

“…The hallucinations began abruptly, were brightly coloured stereotyped figures, animals or objects, and appeared to be provoked by light. As blindness progressed the clarity, frequency and duration of the hallucinations faded. …”

Double blind comparison of ibuprofen and paracetamol for adjunctive treatment of uncomplicated typhoid fever. by Vinh, H, Parry, C, Hanh, V, Chinh, M, House, D, Tham, C, Thao, N, Diep, T, Wain, J, Day, N, White, N, Farrar, J

“…There have been concerns about the safety of antipyretics in typhoid. METHODS: In a double blind randomized study, 80 Vietnamese children with uncomplicated typhoid fever were randomized to receive identical syrup preparations of ibuprofen (10 mg/kg) or paracetamol (12 mg/kg) every 6 h until 36 h after defervescence. …”

A double-blind randomized therapeutic trial of insect repellents for the prevention of malaria in pregnancy. by Mcgready, R, Simpson, J, Htway, M, White, N, Nosten, F, Lindsay, S

Mefloquine prophylaxis prevents malaria during pregnancy: a double-blind, placebo-controlled study. by Nosten, F, ter Kuile, F, Maelankiri, L, Chongsuphajaisiddhi, T, Nopdonrattakoon, L, Tangkitchot, S, Boudreau, E, Bunnag, D, White, N

“…A double-blind, placebo-controlled study of mefloquine antimalarial prophylaxis in pregnancy (> 20 weeks of gestation) was conducted in 339 Karen women living in an area of multidrug-resistant malaria transmission on the Thai-Burmese border. …”

Fever in uncomplicated Plasmodium falciparum malaria: randomized double-'blind' comparison of ibuprofen and paracetamol treatment. by Krishna, S, Pukrittayakamee, S, Supanaranond, W, ter Kuile, F, Ruprah, M, Sura, T, White, N

“…In a randomized, double-'blind' study, we compared a single dose of ibuprofen (10 mg/kg, n = 8) with paracetamol (15 mg/kg, n = 8) for the treatment of fever > 38.5 degrees C due to uncomplicated falciparum malaria. …”

Chloroquine prophylaxis against vivax malaria in pregnancy: a randomized, double-blind, placebo-controlled trial by Villegas, L, Mcgready, R, Htway, M, Paw, M, Pimanpanarak, M, Arunjerdja, R, Viladpai-nguen, S, Greenwood, B, White, N, Nosten, F

“…Method: One thousand pregnant Karen women were enrolled in a randomized, double-blind, placebo-controlled trial of chemoprophylaxis with chloroquine (500 mg phosphate (or 300 mg base) weekly). …”

Interferon alfa-2a in Japanese encephalitis: a randomised double-blind placebo-controlled trial. by Solomon, T, Dung, N, Wills, B, Kneen, R, Gainsborough, M, Diet, T, Thuy, T, Loan, H, Khanh, VC, Vaughn, D, White, N, Farrar, J

“…METHODS: We did a randomised double-blind placebo-controlled trial of interferon alfa-2a (10 million units/m2, daily for 7 days) in 112 Vietnamese children with suspected Japanese encephalitis, 87 of whom had serologically confirmed infections. …”

Fluid resuscitation for dengue shock syndrome - The evidence from formal randomised and blinded intervention trials in Vietnam by Wills, B, Dung, N, Loan, H, Tam, D, Thu, T, Minh, LT, Diet, T, Hao, N, Chau, N, Stepniewska, K, White, N, Farrar, J

Chloroquine prophylaxis against vivax malaria in pregnancy: a randomized, double-blind, placebo-controlled trial. by Villegas, L, Mcgready, R, Htway, M, Paw, M, Pimanpanarak, M, Arunjerdja, R, Viladpai-Nguen, S, Greenwood, B, White, N, Nosten, F

“…METHOD: One thousand pregnant Karen women were enrolled in a randomized, double-blind, placebo-controlled trial of chemoprophylaxis with chloroquine (500 mg phosphate (or 300 mg base) weekly). …”

Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand by Nosten, F, Luxemburger, C, Kyle, D, Ballou, W, Wittes, J, Wah, E, Chongsuphajaisiddhi, T, Gordon, D, White, N, Sadoff, J, Heppner, D, Bathe, K, Blood, J, Brockman, A, Cobley, U, Hacking, D, Hogg, D, U, K, Maelankiri, L, Chuanak, N, Permpanich, B, Price, R, Raimond, D, Schabenberger, O, Singharaj, P

“…We report a randomised double-blind trial of the SPf66 vaccine conducted in Karen children aged 2-15 living in a malarious region of northwestern Thailand. …”

Fluid replacement in dengue shock syndrome: a randomized, double-blind comparison of four intravenous-fluid regimens. by Dung, N, Day, N, Tam, D, Loan, H, Chau, H, Minh, L, Diet, T, Bethell, D, Kneen, R, Hien, T, White, N, Farrar, J

“…Further large-scale double-blind trials are required to provide an evidence-based approach to the management of DSS.…”

N-acetylcysteine as adjunctive treatment in severe malaria: a randomized, double-blinded placebo-controlled clinical trial. by Charunwatthana, P, Abul Faiz, M, Ruangveerayut, R, Maude, R, Rahman, MR, Roberts, L, Moore, K, Bin Yunus, E, Hoque, MG, Hasan, M, Lee, S, Pukrittayakamee, S, Newton, P, White, N, Day, N, Dondorp, A

“…DESIGN: A randomized, double-blind, placebo-controlled trial on the use of high-dose intravenous NAC as adjunctive treatment to artesunate. …”

A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis. by Newton, P, Thai, L, Tip, N, Short, J, Chierakul, W, Rajanuwong, A, Pitisuttithum, P, Chasombat, S, Phonrat, B, Maek-A-Nantawat, W, Teaunadi, R, Lalloo, D, White, N

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria by Lwin, K, Phyo, A, Tarning, J, Hanpithakpong, W, Ashley, E, Lee, S, Cheah, P, Singhasivanon, P, White, N, Lindegårdh, N, Nosten, F

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria. by Lwin, K, Phyo, A, Tarning, J, Hanpithakpong, W, Ashley, E, Lee, S, Cheah, P, Singhasivanon, P, White, N, Lindegårdh, N, Nosten, F

A double-blind placebo-controlled study of an infusion of lexipafant (Platelet-activating factor receptor antagonist) in patients with severe sepsis. by Suputtamongkol, Y, Intaranongpai, S, Smith, MD, Angus, B, Chaowagul, W, Permpikul, C, Simpson, J, Leelarasamee, A, Curtis, L, White, N

“…Platelet-activating factor (PAF) is a potent endogenous proinflammatory mediator implicated in the pathogenesis of septic shock. A double-blind randomized placebo-controlled trial of an intravenous PAF receptor antagonist (lexipafant) was conducted with 131 adult Thai patients with suspected severe sepsis (66 of whom had positive blood cultures). …”

Acute management of dengue shock syndrome: a randomized double-blind comparison of 4 intravenous fluid regimens in the first hour. by Ngo, N, Cao, X, Kneen, R, Wills, B, Nguyen, V, Nguyen, T, Chu, V, Nguyen, T, Simpson, J, Solomon, T, White, N, Farrar, J

“…We undertook a randomized blinded comparison of 4 fluids (dextran, gelatin, lactated Ringer's, and "normal" saline) for initial resuscitation of 230 Vietnamese children with DSS. …”

Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial by Eziefula, A, Bousema, T, Yeung, S, Kamya, M, Owaraganise, A, Gabagaya, G, Bradley, J, Grignard, L, Lanke, K, Wanzira, H, Mpimbaza, A, Nsobya, S, White, N, Webb, E, Staedke, S, Drakeley, C

“…Methods: We undertook this randomised, double-blind, placebo-controlled trial with four parallel groups in Jinja district, eastern Uganda. …”

Single dose primaquine for clearance of Plasmodium falaparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial by Eziefula, A, Bousema, T, Yeung, S, Kamya, M, Owaraganise, A, Gabagaya, G, Bradley, J, Grignard, L, Lanke, K, Wanzira, H, Mpimbaza, A, Nsobya, S, White, N, Webb, E, Staedke, S, Drakeley, C

Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks. by Anekthananon, T, Pukrittayakamee, S, Pukritayakamee, S, Ratanasuwan, W, Jittamala, P, Werarak, P, Charunwatthana, P, Suwanagool, S, Lawpoolsri, S, Stepniewska, K, Sapchookul, P, Puthavathana, P, Fukuda, C, Lindegardh, N, Tarning, J, White, N, Day, N, Taylor, W

“…METHODS: We conducted a parallel group, double blind, 2 (active drug) :1 (placebo) randomized trial of oral oseltamivir/placebo or inhaled zanamivir/placebo over 16 weeks in healthy, Thai hospital professionals at two Bangkok hospitals. …”