Organic aspects of organometallic chemistry by Frost, C, Willis, M

Sulfinamide synthesis using organometallic reagents, DABSO, and amines by Lo, PKT, Oliver, G, Willis, M

“…We report the synthesis of sulfinamides using organometallic reagents, a sulfur dioxide reagent, and nitrogen based-nucleophiles. …”

Combining organometallic reagents, the sulfur dioxide surrogate DABSO, and amines: a one-pot preparation of sulfonamides, amenable to array synthesis. by Deeming, A, Russell, C, Willis, M

“…We describe a method for the synthesis of sulfonamides through the combination of an organometallic reagent, a sulfur dioxide equivalent, and an aqueous solution of an amine under oxidative conditions (bleach). …”

Synthesis of heterocycles via palladium-catalysed direct arylation by Yagoubi, M

Subjects: “…Organometallic Chemistry…”

Development of catalytic methods to exploit sulfur dioxide in organic synthesis by Emmett, EJ

Subjects:

Rhodium catalysed hydroacylation reactions in the synthesis of heterocycles by Ylioja, P

Subjects: “…Organometallic Chemistry…”

Tandem catalytic processes involving Rhodium-catalysed intermolecular hydroacylation by Lenden, P

Subjects:

The 2-pyridyl problem: challenging nucleophiles in cross-coupling arylations by Cook, X, de Gombert, A, McKnight, J, Pantaine, L, Willis, M

“…However, 2‐pyridine organometallics are capricious coupling partners and 2‐pyridyl boron reagents in particular are notorious for their instability and poor reactivity in Suzuki‐Miyaura cross‐coupling reactions. …”

One-pot sulfoxide synthesis exploiting a sulfinyl-dication equivalent generated from a DABSO/Trimethylsilyl Chloride sequence by Willis, M, Lenstra, D, Vedovato, V, Flegeau, E, Maydom, J

“…A one-pot process for the synthesis of unsymmetrical sulfoxides using organometallic nucleophiles is described. Sulfur dioxide, delivered from the surrogate DABSO (DABCO-bis(sulfur dioxide)), acts as the initial electrophile and combines with the first organometallic reagent to generate a sulfinate intermediate. …”

Use and applications of sulfur dioxide surrogates in the synthesis of sulfonyl derivatives by Vedovato, V

“…</p> <p>Chapter 2 describes the development of a one-pot process for the synthesis of unsymmetrical sulfoxides and sulfinamides using organometallic nucleophiles, DABSO, and trimethylsilyl chloride.1 Reacting sulfur dioxide with an organometallic reagent provides a metal-sulfinate intermediate. …”

Modular sulfondiimine and sulfondiimidamide synthesis using stable sulfinylamine reagents by Zhang, Z

“…The use of sulfinylamine linchpins in combination with commercially available organometallic reagents and amines provides access to a broad range of sulfondiimines and sulfondiimidamides.…”

New methods to synthesise sulfur-containing compounds by Lo, PKT

“…</p> <p>Chapter 3 documents the preparation of sulfinamides using organometallic reagents and nitrogen-based nucleophiles in a streamlined one-pot, three-step procedure. …”

One-pot, Three-Component Sulfonimidamide Synthesis exploiting the Sulfinylamine Reagent N-Sulfinyltritylamine, TrNSO by Davies, T, Hall, A, Willis, M

“…We describe a one‐pot de novo synthesis of sulfonimidamides from widely available organometallic reagents and amines. This convenient and efficient process uses a stable sulfinylamine reagent, N‐sulfinyltritylamine (TrNSO), available in one step on 10 gram scale, as a linchpin. …”

Palladium-catalysed addition of aryl halides to N-sulfinylamines for the synthesis of sulfinamides by Wei, M-K, Moseley, D, Bär, R, Sempere, Y, Willis, M

“…The reactions use mild conditions and are achieved without the use of highly reactive pre-formed organometallic reagents, resulting in transformations of broad generality and high functional group tolerance. …”

One-pot, three-component sulfonimidamide synthesis exploiting the sulfinylamine reagent N -sulfinyltritylamine, TrNSO by Davies, T, Hall, A, Willis, M

“…We describe a one-pot de novo synthesis of sulfonimidamides from widely available organometallic reagents and amines. This convenient and efficient process uses a stable sulfinylamine reagent, N-sulfinyltritylamine (TrNSO), available in one step on 10 gram scale, as a linchpin. …”

A modular two-step route to sulfondiimidamides by Zhang, Z, Ding, M, Bell, C, Willis, M

“…The starting materials are organometallic reagents, an unsymmetrical sulfurdiimide, and amines. …”

Exploiting sulfinylamines in synthesis by Davies, TQ

“…The union of sulfinylamines with widely available organometallic reagents and amines allows the rapid construction of complex, medicinally relevant sulfoximine, sulfonimidamide and primary sulfonamide products.…”

New reagents and reactions for the synthesis of sulfinates and their aza-analogues by Andrews, JA

“…</p> <p><strong>Chapter 6</strong> describes studies towards the development of synthetic routes towards new sulfurdiimide reagents and demonstrates their reaction with alkyl radicals or organometallic reagents to prepare challenging aza-sulfur products.…”

Applications of DABSO for the delivery of sulfur dioxide in organic synthesis by Deeming, A

“…</p> <p><b>Chapter 2</b> details the development of a one-pot sulfone synthesis <em>via</em> metal sulfinates generated from organometallic reagents and DABSO. Alkyl, alkenyl and (hetero)aryl sulfinates prepared from organolithium and Grignard reagents can be efficiently coupled with a range of electrophiles to access a range of products including diaryl, aryl-heteroaryl and β-hydroxy sulfones.…”