Palladium- and copper-catalysed heterocycle synthesis by Ball, C

“…This work describes efforts to develop and extend the utility of two of these general heterocycle precursors - <em>ortho</em>-(haloalkenyl)aryl halides A and α-(<em>ortho</em>-haloaryl) ketones B - in conjunction with cascade reactions involving the construction of key carbon-heteroatom bonds <em>via</em> palladium or copper catalysis.</p> <p>Chapter 1 entails an overview of the development of palladium- and copper-catalysed carbon-heteroatom bond forming processes. …”

Palladium-catalyzed aminosulfonylation of aryl halides. by Nguyen, B, Emmett, E, Willis, M

“…The palladium-catalyzed three-component coupling of aryl iodides, sulfur dioxide, and hydrazines to deliver aryl N-aminosulfonamides is described. …”

Palladium-catalyzed alpha-arylation of oxindoles. by Durbin, M, Willis, M

Tandem palladium catalysis: New routes to indoles. by Willis, M, Brace, G, Holmes, I

Palladium catalysed enantioselective desymmetrisation of meso ditriflates. by Willis, M, Claverie, C

Palladium-catalyzed direct functionalization of benzoxazoles with alkenyl iodides by Gerelle, M, Dalencon, A, Willis, M

“…A straightforward procedure for the palladium-catalyzed direct functionalization of benzoxazoles with alkenyl iodides is described. …”

Intramolecular palladium-catalyzed direct arylation of alkenyl triflates. by Cruz, A, Miller, N, Willis, M

Palladium catalysed enamine synthesis from vinyl triflates by Willis, M, Brace, G

Synthesis of heterocycles via palladium-catalysed direct arylation by Yagoubi, M

“…<p>Chapter 1 is a brief review on some of the recents developments in palladium-catalysed C-H functionalisation chemistry. …”

ORGN 134-Desymmetrization of bisvinyltriflates via palladium-catalyzed carbonylation by Byrne, S, Willis, M, Hebeisen, P

Palladium mediated enantioselective desymmetrization of meso 1,1-dihaloalkenes. by Willis, M, Claverie, C

Palladium-catalyzed synthesis of benzimidazoles and quinazolinones from common precursors. by Sadig, J, Foster, R, Wakenhut, F, Willis, M

“…The synthesis of N-substituted benzimidazoles was possible from the palladium-catalyzed reaction of both classes of substrate with a variety of N-nucleophiles. …”

Palladium catalysed aryl enol ether synthesis from vinyl triflates. by Willis, M, Taylor, D, Gillmore, A

Palladium-catalysed C-N bond formation: New tools for synthesis. by Chauhan, J, Willis, M, Whittingham, W

Palladium-catalysed addition of aryl halides to N-sulfinylamines for the synthesis of sulfinamides by Wei, M-K, Moseley, D, Bär, R, Sempere, Y, Willis, M

“…Herein, we report the synthesis of sulfinamides from aryl and alkenyl (pseudo) halides and N-sulfinylamines, enabled by palladium catalysis. The reactions use mild conditions and are achieved without the use of highly reactive pre-formed organometallic reagents, resulting in transformations of broad generality and high functional group tolerance. …”

One-pot sulfonamide synthesis exploiting the palladium-catalyzed sulfination of aryl iodides by Flegeau, E, Harrison, J, Willis, M

Heterocyclic allylsulfones as latent heteroaryl nucleophiles in palladium-catalyzed cross-coupling reactions by Markovic, T, Murray, P, Rocke, B, Shavnya, A, Blakemore, D, Willis, M

“…Heterocyclic sulfinates are effective reagents in palladium-catalyzed coupling reactions with aryl and heteroaryl halides, often providing high yields of the targeted biaryl. …”

Cascade Palladium- and Copper-Catalysed Aromatic Heterocycle Synthesis: The Emergence of General Precursors by Ball, C, Willis, M

“…This microreview focuses on the development and use of four of these starting material types in cascade reactions involving the palladium- or copper-catalysed formation of aromatic carbon-nitrogen, carbon-oxygen or carbon-sulfur bonds. …”

One-pot palladium-catalyzed synthesis of sulfonyl fluorides from aryl bromides by Davies, A, Curto, J, Bagley, S, Willis, M

“…A mild, efficient synthesis of sulfonyl fluorides from aryl and heteroaryl bromides utilizing palladium catalysis is described. The process involves the initial palladium catalyzed sulfonylation of aryl bromides using DABSO as an SO2 source, followed by in situ treatment of the resultant sulfinate with the electrophilic fluorine source NFSI. …”

Benzosultam synthesis exploiting sequential palladium-catalysed intermolecular aminosulfonylation and intramolecular sulfamidation by Richards-Taylor, C, Willis, M

“…We report a route to benzosultams that exploits the palladium-catalysed aminsulfonylation of alkenyl iodides as the initial step. …”