THE ROLE OF ALPHA-6 BETA-4-INTEGRINS IN BLISTER DEVELOPMENT IN BULLOUS PEMPHIGOID by Venning, V, Allen, J, Kirtschig, G, Aplin, J, Wojnarowska, F

The distribution of alpha 6 beta 4 integrins in lesional and non-lesional skin in bullous pemphigoid. by Venning, V, Allen, J, Aplin, J, Kirtschig, G, Wojnarowska, F

“…Within BP blisters, both alpha 6 and beta 4 integrin subunits and BPA were absent, except in two blisters in which the integrin expression was retained in the blister roof, despite loss of BPA. …”

Alterations in the basement membrane zone in pili annulati hair follicles as demonstrated by electron microscopy and immunohistochemistry. by Giehl, K, Ferguson, D, Dean, D, Chuang, Y, Allen, J, Berker, D, Tosti, A, Dawber, R, Wojnarowska, F

“…The expression of the hemidesmosome-associated alpha(6)beta(4) integrin was linear in both pili annulati and control hair follicles. …”

The basement membrane zone of the nail. by Sinclair, R, Wojnarowska, F, Leigh, I, Dawber, R

“…In particular, there was normal expression of the epidermal-associated antigens, the 220- and 180-kDa bullous pemphigoid antigens, and the alpha 6 beta 4 integrin. There was also normal expression of the lamina lucida antigens LH39, GB3 and laminin. …”

The basement membrane zone and dermal extracellular matrix in erosive lichen planus of the vulva: an immunohistochemical study demonstrating altered expression of hemidesmosome com... by Cooper, S, Prenter, A, Allen, J, Dean, D, Wojnarowska, F

“…This study has demonstrated widespread damage to the BMZ in erosive LP of the vulva, in particular the hemidesmosomes (alpha6beta4 integrin, BP230, BP180) and anchoring fibrils (collagen VII). …”

Physicochemical characterization and differentiation of the components of the cutaneous basement membrane zone. by Allen, J, Schomberg, K, Wojnarowska, F

“…The results showed that chemical modification by sodium chloride, calcium chloride and ethylenediaminetetraacetic acid, and incubation in 0.15 mol/L NaCl at 56 degrees C for 1 min did not adversely affect the expression of the alpha 6 beta 4 integrin, laminin-5, the LH39 antigen, laminin-1, collagen type IV or collagen type VII. …”

Comparison between the expression of basement membrane zone antigens of human interfollicular epidermis and anagen hair follicle using indirect immunofluorescence. by Chuang, Y, Dean, D, Allen, J, Dawber, R, Wojnarowska, F

“…There was weak or even negative staining with antibodies to alpha 6 beta 4 integrin, laminin-5, anchoring filaments, and type VII collagen in the outer aspect of the bulb compared with the hair papilla. …”

A comparison of the expression of known basement membrane components with the linear IgA disease antigens using the novel substrate cylindroma. by Wojnarowska, F, Allen, J, Collier, P, Leigh, I

“…This was similar to the pattern observed with antibodies to the hemidesmosome components, the alpha6beta4 integrin and the bullous pemphigoid antigens BP230 and BP180. …”

Upregulation of adhesion complex proteins and fibronectin by human keratinocytes treated with an aqueous extract from the leaves of Chromolaena odorata (Eupolin) by Phan, T, Allen, J, Hughes, M, Cherry, G, Wojnarowska, F

“…The expression of the β1 and β4 integrins was upregulated by the extract at low concentrations (0.1 and 1 μg/ml), but the expression was decreased at higher doses of Eupolin (10 μg-150 μg/ml). …”

Upregulation of adhesion complex proteins and fibronectin by human keratinocytes treated with an aqueous extract from the leaves of Chromolaena odorata (Eupolin). by Phan, T, Allen, J, Hughes, M, Cherry, G, Wojnarowska, F

“…The expression of the b1 and b4 integrins was upregulated by the extract at low concentrations (0.1 and 1 microg/ml), but the expression was decreased at higher doses of Eupolin (10 microg-150 microg/ml). …”