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Linc00996 is a favorable prognostic factor in LUAD: Results from bioinformatics analysis and experimental validation
Published 2022-09-01“…Finally, the clinical impact of Linc00996 was assessed in 61 patients with LUAD, and the biological functions of Linc00996 were determined by a series of experiments in vitro, such as CCK8, colony formation, migration, and invasion assays.Results: Compared with adjacent normal lung tissues, Linc00996 was significantly downregulated in LUAD, and its expression was negatively correlated with T stage, N stage, and pathological stage. …”
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Study on the Pre-Oxidation and Resulting Oxidation Mechanism and Kinetics of Mo-9Si-8B Alloy
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Structural alterations of brain in different disease states of Crohn's disease: Results of a cross-sectional study in a Chinese hospital
Published 2024-03-01“…Pearson correlation analysis was used to evaluate the relationships. Results: The CSF volume was negatively correlated with the disease duration in CD-R. …”
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BALF metagenomic next-generation sequencing analysis in hematological malignancy patients with suspected pulmonary infection: clinical significance of negative results
Published 2023-06-01“…The final diagnosis, imaging findings, laboratory results and treatment regimen of 29 mNGS-negative patients were mainly analyzed.ResultsA total of 83 mNGS positive and 29 negative patients (15 true-negatives and 14 false-negatives) were included in the study. …”
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Is disease activity associated with social support and psychological distress in Crohn’s disease patients? Results of a cross-sectional study in a Chinese hospital population
Published 2023-10-01“…The association of disease activity, social support and psychological distress with patients with CD was also evaluated based on the collected data.Results A total of 162 patients with CD were enrolled. …”
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Domain Swapping between AtACS7 and PpACL1 Results in Chimeric ACS-like Proteins with ACS or C<sub>β</sub>-S Lyase Single Enzymatic Activity
Published 2023-02-01“…The activities of both chimeric proteins were compared with previously obtained single-activity mutants including R6, AtACS7<sup>Q98A</sup>, and AtACS7<sup>D245N</sup>. All the results provided new insights into the key residues required for ACS and CSL activities of AtACS7 and laid an important foundation for further in-depth study of the biological functions of its dual enzymatic activities.…”
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Thermo-mechanical modeling of thermal stress during multi-cycle intense pulsed light sintering of thick conductive wires on 3D printed dark substrate
Published 2023-01-01“…Results in Physics…”
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Improving the efficiency of chemical synthesis of disulfide-containing proteins via oxidative folding optimization
Published 2023-12-01“…Results in Chemistry…”
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First-principles calculations to investigate probing the influence of Mn and Mg doping concentration on electronic structures and transport properties of SnTe alloys
Published 2023-05-01“…Results in Physics…”
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Construction of TiO2 microsphere through different titanium precursors via a green pathway
Published 2022-01-01“…Results in Chemistry…”
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High-throughput screening giant bulk spin-split materials
Published 2023-06-01“…Results in Physics…”
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Normative reference data for body composition in healthy indigenous populations on the Qinghai-Tibet Plateau
Published 2022-10-01“…Age-, sex-, and altitude-specific alterations in body composition values also inform the prevention and amendment of abnormal body composition changes and resultant health complications.…”
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Site selection of desert solar farms based on heterogeneous sand flux
Published 2024-03-01“…The scoring result demonstrates that global deserts have obvious patchy distribution of site suitability for building solar farms. …”
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ZmG6PDH1 in glucose-6-phosphate dehydrogenase family enhances cold stress tolerance in maize
Published 2023-03-01“…Significant changes in the redox status of the NADPH, ascorbic acid (ASA), and glutathione (GSH) pools were observed after exposure of the zmg6pdh1 mutants to cold stress, with this disrupted redox balance contributing to increased production of reactive oxygen species and resultant cellular damage and death. Overall, these results highlight the importance of cytosolic ZmG6PDH1 in supporting maize resistance to cold stress, at least in part by producing NADPH that can be used by the ASA-GSH cycle to mitigate cold-induced oxidative damage.…”
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Spread of MCR-3 Colistin Resistance in China: An Epidemiological, Genomic and Mechanistic StudyResearch in Context
Published 2018-08-01“…Additionally, the expression of MCR-3 in E. coli prevents the colistin-triggered formation of reactive oxygen species (ROS) and interferes bacterial growth and viability. Interpretation: Our results provide an evolutionary, structural and functional definition of MCR-3 and its epidemiology in China, paving the way for smarter policies, better surveillance and effective treatments. …”
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Study on the mechanical characteristics of sand pebble surrounding rock considering the disturbance effect of tunnel excavation
Published 2024-03-01“…Furthermore, a revised constitutive model based on this unified disturbance function is established for the first time. The study results indicated that the results calculated by traditional models, which do not take into account disturbance effects, deviate from the experimental results by more than 20%. …”
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Dynamic Responses for WindFloat Floating Offshore Wind Turbine at Intermediate Water Depth Based on Local Conditions in China
Published 2021-10-01“…A comparison between the coupled method and simplified method shows that the calculated results are slightly different between the different conditions for the time domain results, response spectra results, and fatigue results. …”
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Seismic Behavior of Box Steel Bridge Pier with Built-In Energy Dissipation Steel Plates
Published 2022-01-01“…Finite element models of steel bridge piers were established and compared with the test results. The analysis results using FEM agree well with the test results. …”
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Effects of Sodium Chloride on the Physical and Oxidative Stability of Filled Hydrogel Particles Fabricated with Phase Separation Behavior
Published 2021-05-01“…Moreover, rheological characterization revealed that the apparent viscosity and viscoelastic behavior gradually decreased at higher NaCl concentration, which was mainly ascribed to the influence of NaCl on the electrostatic repulsion between droplets, thereby adversely impacting the physical stability of filled hydrogels. Furthermore, the result of cryo-scanning electron microscopy also verified the abovementioned results. …”
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