Osimertinib inhibits brain metastases and improves long-term survival in a patient with advanced squamous cell lung cancer: a case report and literatures review by Zhiqin Zhang, Zhiqin Zhang, Jiamao Lin, Linke Yang, Yang Li

“…BackgroundSquamous cell carcinoma (SCC) is one of the most common subtypes of non-small cell lung cancer, but its treatment options remain limited. Epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) have limited efficacy in the treatment of lung SCC. …”
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Responses of Phaseolus calcaltus to lime and biochar application in an acid soil by Luhua Yao, Xiangyu Yu, Lei Huang, Xuefeng Zhang, Dengke Wang, Xiao Zhao, Yang Li, Zhibin He, Lin Kang, Xiaoting Li, Dan Liu, Qianlin Xiao, Yanjun Guo

“…Introduction Rice bean (Phaseolus calcaltus), as an annual summer legume, is always subjected to acid soils in tropical to subtropical regions, limiting its growth and nodulation. However, little is known about its responses to lime and biochar addition, the two in improving soil fertility in acid soils. …”
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Stoichiometric homeostasis of N:P ratio drives species-specific symbiotic N fixation inhibition under N addition by Qiang Li, Qiang Li, Joshua Philp, Matthew D. Denton, Yingxin Huang, Yingxin Huang, Jian Wei, Huijuan Sun, Huijuan Sun, Yang Li, Yang Li, Qian Zhao

“…The changes in symbiotic N fixation were positively correlated with stoichiometric homeostasis of N:P ratios in intact plants without root nodules, regardless of P additions.DiscussionThis study indicates that N addition can induce relative P limitations for growth, which can stimulate rhizosphere P mobilization at the expense of root biomass and carbohydrate concentrations, reducing symbiotic N fixation in legumes. …”
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