Traditional Tibetan medicine: therapeutic potential in rheumatoid arthritis by Liqiong Yu, Shiling Li, Lili Pu, Chunhong Yang, Qian Shi, Qi Zhao, Shengbu Meniga, Yue Liu, Yi Zhang, Xianrong Lai, Xianrong Lai

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Methylthioadenosine phosphorylase deficiency in tumors: A compelling therapeutic target by Na Fan, Yi Zhang, Suyun Zou

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Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy by Li Yang, Aitian Li, Ying Wang, Yi Zhang

“…These viewpoints may help identify the microbiota as diagnosis or prognosis evaluation of cancers, and as new therapeutic strategy and potential therapeutic targets for cancer therapy.…”
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How autophagy, a potential therapeutic target, regulates intestinal inflammation by Shuang-Lan Chen, Chun-Meng Li, Wei Li, Qing-Song Liu, Shuang-Yuan Hu, Mao-Yuan Zhao, Dong-Sen Hu, Yan-Wei Hao, Jin-Hao Zeng, Jin-Hao Zeng, Yi Zhang

“…A better understanding of the mechanism of autophagy in the occurrence and progression of IBD will provide references for the development of therapeutic drugs and disease management for IBD in the future.…”
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Managing metabolic diseases: The roles and therapeutic prospects of herb-derived polysaccharides by Xinmei Xu, Lijie Wang, Kun Zhang, Yi Zhang, Gang Fan

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Multimodal sensing and therapeutic systems for wound healing and management: A review by Shao-Hao Lu, Mohamadmahdi Samandari, Caihong Li, Huijie Li, Dongjin Song, Yi Zhang, Ali Tamayol, Xueju Wang

“…This review paper introduces recent progress on multimodal sensing and therapeutic systems for wound healing. Specifically, we focus on physical sensing (temperature, moisture, pressure, and strain), chemical sensing (pH, uric acid, and cytokine), as well as therapeutic systems for wound management (active drug delivery systems based on external stimulations and non-drug stimulations). …”
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Molecular landscape and emerging therapeutic strategies in breast cancer brain metastasis by Siyi Xiong, Xuanni Tan, Xiujuan Wu, Andi Wan, Guozhi Zhang, Cheng Wang, Yan Liang, Yi Zhang

“…Therapeutic Advances in Medical Oncology…”
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Mediating a host cell signaling pathway linked to overwinter mortality offers a promising therapeutic approach for improving bee health by Yi Zhang, Andrew Liu, Shao Kang Huang, Jay D. Evans, Steve C. Cook, Evan Palmer-Young, Miguel Corona, Mohamed Alburaki, Ge Liu, Ri Chou Han, Wen Feng Li, Yue Hao, Ji Lian Li, Todd M. Gilligan, Allan H. Smith-Pardo, Olubukola Banmeke, Francisco J. Posada-Florez, Ya Hui Gao, Gloria DeGrandi-Hoffman, Hui Chun Xie, Alex M. Sadzewicz, Michele Hamilton, Yan Ping Chen

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Therapeutic potential of Lonicerae japonicae flos against emerging respiratory viral infections by Juan Yang, Baomei Xia, Yanyan Han, Youming Wang, Yuhai Bi, Yi Zhang

“…This review concentrated on summarizing the roles and mechanism of LJF on the treatment of respiratory infections, and analyzing the potential therapeutic values of emerging respiratory infectious disease. …”
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Dissecting cellular heterogeneity and intercellular communication in cholangiocarcinoma: implications for individualized therapeutic strategies by Zun-Qiang Zhou, Yi Zhang, Zi-Yang Xu, Xiao-Li Tang, Xiao-Hua Chen, Jiao Guan, Zheng-Yun Zhang

“…Background: Cholangiocarcinoma is characterized by significant cellular heterogeneity and complex intercellular communication, which contribute to its progression and therapeutic resistance. Therefore, unraveling this complexity is essential for the development of effective treatments.Methods: We employed single-cell RNA sequencing (scRNA-seq) to investigate cellular heterogeneity and intercellular communication in cholangiocarcinoma and adjacent normal tissues from two patients. …”
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Industrial-Scale Preparation of a Key Intermediate for the Manufacture of Therapeutic SGLT2 Inhibitors by Lei Huang, Yi Zhang, Xiao-Hui Shan, Yu Liu, Jian-Qi Li

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Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma by Jia-Ying Yuan, Xiang-Yun Wang, Zhi-Ying Tong, Yu-Chao Dong, Jia-Yi Zhao, Yi Zhang, Yan Shang

“…Extracellular vesicles (EVs) enriched in body fluid were characterized as subcomponents of extracellular vesicles and delivered carriers combined with genetic messages in vivo. The therapeutic potential of exosomes has become a research hotspot in many diseases. …”
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Pyrotinib-based therapeutic approaches for HER2-positive breast cancer: the time is now by Xiaowei Qi, Qiyun Shi, Juncheng Xuhong, Yi Zhang, Jun Jiang

“…This review highlights the development on the application of pyrotinib-based therapeutic approaches in the clinical settings of HER2-positive BC.…”
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The therapeutic targets of N6-methyladenosine (m6A) modifications on tumor radioresistance by Yi Zhang, Wendong Gu, Yingjie Shao

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Therapeutic effect of Bacillus Calmette–Guerin polysaccharide nucleic acid on mast cell at the transcriptional level by Siyu Yan, Runqiu Liu, Manyun Mao, Zhaoqian Liu, Wei Zhang, Yi Zhang, Jie Li, Cong Peng, Xiang Chen

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Induced CAR-Macrophages as a Novel Therapeutic Cell Type for Cancer Immune Cell Therapies by Siyu Su, Anhua Lei, Xudong Wang, Hengxing Lu, Shuhang Wang, Yuqi Yang, Ning Li, Yi Zhang, Jin Zhang

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Advancements in microemulsion-based fabrication of upconversion-mediated multifunctional materials by Yi Zhang, Qingsong Mei, Zhen Zhang

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Targeting the mechano-microenvironment and liver cancer stem cells: a promising therapeutic strategy for liver cancer by Xiaorong Fu, Yi Zhang, Qing Luo, Yang Ju, Guanbin Song

“…Targeting CSCs is a novel therapeutic strategy for cancer management and treatment. …”
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Construction and validation of a novel lysosomal signature for hepatocellular carcinoma prognosis, diagnosis, and therapeutic decision-making by Jianlin Chen, Gan Gao, Yufang He, Yi Zhang, Haixia Wu, Peng Dai, Qingzhu Zheng, Hengbin Huang, Jiamiao Weng, Yue Zheng, Yi Huang

“…This study provided a direct links between LRRS signature and clinical characteristics, tumor microenvironment, and clinical drug-response, highlighting the critical role of lysosome in the development and treatment resistance of liver cancer, providing valuable insights into the prognosis prediction and treatment response of HCC, thereby providing valuable insights into prognostic prediction, early diagnosis, and therapeutic response of HCC.…”
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Single cell profiling of female breast fibroadenoma reveals distinct epithelial cell compositions and therapeutic targets by Zhigang Chen, Yi Zhang, Wenlu Li, Chenyi Gao, Fengbo Huang, Lu Cheng, Menglei Jin, Xiaoming Xu, Jian Huang

“…Thus, our study presents an overview of human FA at single-cell resolution that outlines the structural and functional differences between FA and normal breast epithelium and, in particular, provides a potential therapeutic strategy for breast FAs.…”
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