Subicular circuit in epilepsy: deconstruct heterogeneity for precise therapeutics by Ying Wang, Mengru Liu, Qingyu Wang

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Trends in insulin resistance: insights into mechanisms and therapeutic strategy by Mengwei Li, Xiaowei Chi, Ying Wang, Sarra Setrerrahmane, Wenwei Xie, Hanmei Xu

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Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy by Li Yang, Aitian Li, Ying Wang, Yi Zhang

“…These viewpoints may help identify the microbiota as diagnosis or prognosis evaluation of cancers, and as new therapeutic strategy and potential therapeutic targets for cancer therapy.…”
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Targeting Inflammasome Activation in Viral Infection: A Therapeutic Solution? by Chuan-Han Deng, Tian-Qi Li, Wei Zhang, Qi Zhao, Ying Wang

“…We also discuss the current achievement of the mechanisms involved in viral infection-induced inflammatory response, host defense, and possible therapeutic solutions.…”
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Aged mesenchymal stem cells and inflammation: from pathology to potential therapeutic strategies by Xue Yang, Ying Wang, Valentina Rovella, Eleonora Candi, Wei Jia, Francesca Bernassola, Pierluigi Bove, Mauro Piacentini, Manuel Scimeca, Giuseppe Sica, Giuseppe Tisone, Alessandro Mauriello, Lixin Wei, Gerry Melino, Yufang Shi

“…It is necessary to explore the relationship between the “inflammaging” and aged MSCs to prevent age-related diseases and increase the therapeutic effects of MSCs. In this review, we discuss changes in naturally ageing MSCs mainly from an inflammation perspective and propose some ideas for rejuvenating aged MSCs in future treatments.…”
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Therapeutic angiogenesis based on injectable hydrogel for protein delivery in ischemic heart disease by Junke Wang, Yancheng Song, Wenjie Xie, Jiang Zhao, Ying Wang, Wenzhou Yu

“…Furthermore, the current challenges of therapeutic angiogenesis in IHD and its potential solutions are discussed to facilitate real translation into clinical applications in the future.…”
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NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice by Ruolin Zhang, Weibing Mao, Lumeng Niu, Wendai Bao, Yiqi Wang, Ying Wang, Yasha Zhu, Zhihao Yang, Jincao Chen, Jiawen Dong, Meng Cai, Zilong Yuan, Haikun Song, Guangqiang Li, Min Zhang, Nanxiang Xiong, Jun Wei, Zhiqiang Dong

“…Transplantation of neural stem cells (NSCs) has been proved to promote functional rehabilitation of brain lesions including ischemic stroke. However, the therapeutic effects of NSC transplantation are limited by the low survival and differentiation rates of NSCs due to the harsh environment in the brain after ischemic stroke. …”
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Unraveling the Intricate Roles of Exosomes in Cardiovascular Diseases: A Comprehensive Review of Physiological Significance and Pathological Implications by Shuai Zhang, Yu Yang, Xinchen Lv, Wendong Liu, Shaohua Zhu, Ying Wang, Hongfei Xu

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Multi-level characteristics recognition of cancer core therapeutic targets and drug screening for a broader patient population by Yangguang Su, Ying Wang, Zhuo Qu, Jiaxin Liu, Xuekun Ren, Denan Zhang, Xiujie Chen

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Factors that contribute to poor adherence to statin therapy in coronary heart disease patients from Chongqing and measures to improve their therapeutic outcomes by Guiquan Yu, Yingjiao Zhang, Ying Wang, Guanglei Chang, Hongmei Tao, Dongying Zhang

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Diagnostic and therapeutic strategies for vascular complications after renal transplantation: a single-center experience in 2,304 renal transplantations by Jiangwei Zhang, Wujun Xue, Puxun Tian, Jin Zheng, Chenguang Ding, Yang Li, Ying Wang, Xiaoming Ding

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Decreased Expression of KLF4 Leading to Functional Deficit in Pediatric Patients with Intestinal Failure and Potential Therapeutic Strategy Using Decanoic Acid by Junkai Yan, Yuling Zhao, Lu Jiang, Ying Wang, Wei Cai

“…By using IF patient-derived intestinal organoids and Caco-2 cells as in vitro models, we demonstrated that the supplementation of decanoic acid (DA) could significantly induce the expression of KLF4 along with SLC6A4 and SLC7A9, suggesting that DA may function as a potential therapeutic strategy to promote cell maturation and functional improvement. …”
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Therapeutic Potential of <i>Bacteroides fragilis</i> SNBF-1 as a Next-Generation Probiotic: In Vitro Efficacy in Lipid and Carbohydrate Metabolism and Antioxidant Activity by Weihe Cang, Xuan Li, Jiayi Tang, Ying Wang, Delun Mu, Chunting Wu, Haisu Shi, Lin Shi, Junrui Wu, Rina Wu

“…Overall, this research significantly enhances our understanding of NGPs and their potential therapeutic applications in modulating the gut microbiome.…”
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Clinical characteristics, treatment, and survival of 30 patients with gastrointestinal natural killer/T‐cell lymphoma by Jia‐Xin Liu, Xin Liu, Yong Yang, Wei‐Ping Liu, Ying Wang, Xia He, Li‐Ling Zhang, Bao‐Lin Qu, Li‐Ting Qian, Xiao‐Rong Hou, Xue‐Ying Qiao, Hua Wang, Gao‐Feng Li, Yuan Zhu, Jian‐Zhong Cao, Jun‐Xin Wu, Tao Wu, Su‐Yu Zhu, Mei Shi, Hui‐Lai Zhang, Hang Su, Yu‐Jing Zhang, Jun Zhu, Shu‐Nan Qi, Ye‐Xiong Li, Yu‐Qin Song

Subjects: “…asparaginase/therapeutic use…”
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The potential of targeting cuproptosis in the treatment of kidney renal clear cell carcinoma by Guojie Lei, Lusheng Tang, Yanhua Yu, Wenxia Bian, Lingyan Yu, Junyu Zhou, Yanchun Li, Ying Wang, Jing Du

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LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma by Yuan Li, Shumei Song, Melissa Pool Pizzi, Guangchun Han, Ailing W. Scott, Jiankang Jin, Yan Xu, Ying Wang, Longfei Huo, Lang Ma, Christopher Vellano, Xiaolin Luo, Robert MacLeod, Linghua Wang, Zhenning Wang, Jaffer A. Ajani

Subjects: “…gastric adenocarcinoma and therapeutic target…”
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Post-therapeutic circulating tumor cell-associated white blood cell clusters predict poor survival in patients with advanced driver gene-negative non-small cell lung cancer by Ying Wang, Yanxia Liu, Zhiyun Zhang, Baohua Lu, Yuan Gao, Li Tong, Mingming Hu, Peter Ping Lin, Baolan Li, Tongmei Zhang

“…Patients with CTCs < 5/6ml or with CTC-WBC clusters undetectable exhibited a better treatment response than patients with pre-therapeutic aneuploid CTCs ≥ 5/6ml or harboring CTC-WBC clusters (p = 0.034 and p = 0.012, respectively). …”
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The functions and roles of sestrins in regulating human diseases by Yitong Chen, Tingben Huang, Zhou Yu, Qiong Yu, Ying Wang, Ji’an Hu, Jiejun Shi, Guoli Yang

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Effect of Annexin A2 on prognosis and sensitivity to immune checkpoint plus tyrosine kinase inhibition in metastatic renal cell carcinoma by Jiajun Wang, Jinglai Lin, Jiahao Wang, Ying Wang, Yanjun Zhu, Xianglai Xu, Jianming Guo

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LncRNA LINK‐A Remodels Tissue Inflammatory Microenvironments to Promote Obesity by Yu Chen, Hui Chen, Ying Wang, Fangzhou Liu, Xiao Fan, Chengyu Shi, Xinwan Su, Manman Tan, Yebin Yang, Bangxing Lin, Kai Lei, Lei Qu, Jiecheng Yang, Zhipeng Zhu, Zengzhuang Yuan, Shanshan Xie, Qinming Sun, Dante Neculai, Wei Liu, Qingfeng Yan, Xiang Wang, Jianzhong Shao, Jian Liu, Aifu Lin

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