Liver development during Xenopus tropicalis metamorphosis is controlled by T3-activation of WNT signaling by Yuta Tanizaki, Shouhong Wang, Hongen Zhang, Yuki Shibata, Yun-Bo Shi

“…Liver remodeling during anuran metamorphosis resembles liver maturation in mammals and is controlled by T3. We generated Xenopus tropicalis animals with both TRα and TRβ genes knocked out and found that TR double knockout liver had developmental defects such as reduced cell proliferation and failure to undergo hepatocyte hypertrophy or activate urea cycle gene expression. …”
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Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax by Shouhong Wang, Yuki Shibata, Liezhen Fu, Yuta Tanizaki, Nga Luu, Lingyu Bao, Zhaoyi Peng, Yun-Bo Shi

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Modulation of thyroid hormone-dependent gene expression in Xenopus laevis by INhibitor of Growth (ING) proteins. by Caren C Helbing, Mary J Wagner, Katherine Pettem, Jill Johnston, Rachel A Heimeier, Nik Veldhoen, Frank R Jirik, Yun-Bo Shi, Leon W Browder

“…We have previously shown that ING1 and ING2 expression is regulated by thyroid hormone (TH) during metamorphosis of the Xenopus laevis tadpole. The present study investigates the possibility that ING proteins modulate TH action.Tadpoles expressing a Xenopus ING2 transgene (Trans(ING2)) were significantly smaller than tadpoles not expressing the transgene (Trans(GFP)). …”
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Cell cycle activation in thyroid hormone-induced apoptosis and stem cell development during Xenopus intestinal metamorphosis by Yuta Tanizaki, Yuki Shibata, Wonho Na, Yun-Bo Shi

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Competitive PCR with dual fluorescent primers enhances the specificity and reproducibility of genotyping animals generated from genome editing by Liezhen Fu, Emily Ma, Morihiro Okada, Yuki Shibata, Yun-Bo Shi

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Thyroid Hormone Receptor α Controls the Hind Limb Metamorphosis by Regulating Cell Proliferation and Wnt Signaling Pathways in <i>Xenopus</i> <i>tropicalis</i> by Yuta Tanizaki, Yuki Shibata, Hongen Zhang, Yun-Bo Shi

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Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but Not Adult Intestinal Morphogenesis during <i>Xenopus tropicalis</i> Metamorphosis by Yuki Shibata, Yuta Tanizaki, Hongen Zhang, Hangnoh Lee, Mary Dasso, Yun-Bo Shi

Subjects: “…<i>Xenopus</i> <i>tropicalis</i>…”
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Simplifying Genotyping of Mutants from Genome Editing with a Parallel qPCR-Based iGenotype Index by Liezhen Fu, Shouhong Wang, Lusha Liu, Yuki Shibata, Morihiro Okada, Nga Luu, Yun-Bo Shi

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