First person – Yuta Koui

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Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway by Yogesh Goyal, Thomas J. Levario, Henry H. Mattingly, Susan Holmes, Stanislav Y. Shvartsman, Hang Lu

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Contribution of model organism phenotypes to the computational identification of human disease genes by Sarah M. Alghamdi, Paul N. Schofield, Robert Hoehndorf

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A year at the forefront of plasmodesmal biology by Andrea Paterlini

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First person – Andy Shao

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Natural history of a mouse model of X-linked myotubular myopathy by Ege Sarikaya, Nesrin Sabha, Jonathan Volpatti, Emanuela Pannia, Nika Maani, Hernan D. Gonorazky, Alper Celik, Yijng Liang, Paula Onofre-Oliveira, James J. Dowling

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The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption by Sachin Wani, Anna Daroszewska, Donald M. Salter, Rob J. van ‘t Hof, Stuart H. Ralston, Omar M. E. Albagha

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The ‘39 steps’: an algorithm for performing statistical analysis of data on energy intake and expenditure by John R. Speakman, Quinn Fletcher, Lobke Vaanholt

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First person – Brandon Hastings

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Consensus guidelines on the construct validity of rodent models of restless legs syndrome by Aaro V. Salminen, Stefan Clemens, Diego García-Borreguero, Imad Ghorayeb, Yuqing Li, Mauro Manconi, William Ondo, David Rye, Jerome M. Siegel, Alessandro Silvani, John W. Winkelman, Richard P. Allen, Sergi Ferré, the International Restless Legs Syndrome Study Group (IRLSSG)

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Pulling back the curtain: live imaging adult disease processes by Kristen M. Kwan

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Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction by Melissa Touvron, Brigitte Escoubet, Mathias Mericskay, Aude Angelini, Luciane Lamotte, Maria Paola Santini, Nadia Rosenthal, Dominique Daegelen, David Tuil, Jean-François Decaux

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First person – Ishani Mukherjee

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Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy by Yonghe Ding, Mingmin Wang, Haisong Bu, Jiarong Li, Xueying Lin, Xiaolei Xu

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Intrinsic and extrinsic regulation of rhabdomyolysis susceptibility by Tango2 by Euri S. Kim, Jennifer G. Casey, Brian S. Tao, Arian Mansur, Nishanthi Mathiyalagan, E. Diane Wallace, Brandie M. Ehrmann, Vandana A. Gupta

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See[ing] elegance in sensory biology: an interview with Piali Sengupta by Piali Sengupta

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First person – Michelle Urman

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Unbound (bioavailable) IGF1 enhances somatic growth by Sebastien Elis, Yingjie Wu, Hayden-William Courtland, Dara Cannata, Hui Sun, Mordechay Beth-On, Chengyu Liu, Hector Jasper, Horacio Domené, Liliana Karabatas, Clara Guida, Jelena Basta-Pljakic, Luis Cardoso, Clifford J. Rosen, Jan Frystyk, Shoshana Yakar

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Glycosphingolipids are linked to elevated neurotransmission and neurodegeneration in a Drosophila model of Niemann Pick type C by Anna E. Eberwein, Swarat S. Kulkarni, Emma Rushton, Kendal Broadie

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Acute frataxin knockdown in induced pluripotent stem cell-derived cardiomyocytes activates a type I interferon response by M. Grazia Cotticelli, Shujuan Xia, Rachel Truitt, Nicolai M. Doliba, Andrea V. Rozo, John W. Tobias, Taehee Lee, Justin Chen, Jill S. Napierala, Marek Napierala, Wenli Yang, Robert B. Wilson

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