Showing 1 - 12 results of 12 for search '"therapeutics"', query time: 0.06s Refine Results
  1. 1
  2. 2

    With No Lysine Kinase 3 (WNK3); A Target Enabling Package by Bullock, A

    Published 2018
    “…Gain of function mutations in WNK kinases are found in Gordon’s hypertension syndrome suggesting the WNK pathway as a therapeutic target. WNK3 inhibition in particular has also been shown to reduce cerebral injury after Ischemic stroke. …”
    Dataset
  3. 3

    With No Lysine Kinase 3 (WNK3); A Target Enabling Package by Pinkas, D

    Published 2018
    “…Gain of function mutations in WNK kinases are found in Gordon’s hypertension syndrome suggesting the WNK pathway as a therapeutic target. WNK3 inhibition in particular has also been shown to reduce cerebral injury after Ischemic stroke. …”
    Dataset
  4. 4

    With no lysine kinase 3 (WNK3); A Target Enabling Package by Pinkas, D

    Published 2018
    “…Gain of function mutations in WNK kinases are found in Gordon’s hypertension syndrome suggesting the WNK pathway as a therapeutic target. WNK3 inhibition in particular has also been shown to reduce cerebral injury after Ischemic stroke. …”
    Dataset
  5. 5

    Sonoluminescence from microbubbles at 1 MHz by Beguin, E

    Published 2019
    “…This could be exploited both for diagnostic and therapeutic applications, significantly increasing the range of applications that are currently restricted by the limited penetration of light in the tissue.…”
    Dataset
  6. 6

    LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package by Mathea, S

    Published 2018
    “…Here we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex, as well as multiple assays for small molecule inhibitor screening. …”
    Dataset
  7. 7

    LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package by Bullock, A

    Published 2018
    “…Here we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex, as well as multiple assays for small molecule inhibitor screening. …”
    Dataset
  8. 8

    LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package by Mathea, S

    Published 2018
    “…Here we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex, as well as multiple assays for small molecule inhibitor screening. …”
    Dataset
  9. 9

    Books, Minds, and Bodies: raw transcript text plus VAD values by Carney, J P, Troscianko, E T, Holman, E

    Published 2021
    “…The project was designed to investigate the therapeutic potential of shared reading, and involved running 2 reading groups over 2 consecutive terms and recording participants' discussions of the texts being read aloud together. …”
    Dataset
  10. 10

    Books, Minds, and Bodies dataset by Troscianko, E, Carney, J, Holman, E

    Published 2022
    “…The project was designed to investigate the therapeutic potential of shared reading, and involved running 2 reading groups over 2 consecutive terms and recording participants' discussions of the texts being read aloud together. …”
    Dataset
  11. 11

    Sonothrombolysis with magnetically targeted microbubbles by de Saint Victor, M

    Published 2019
    “…There are 5 sections: 1) Magnetic field caracterisation: magnitude of the magnetic field and of the magnetic field gradient in the experimental setup (used in figure 2) 2) Accumulation of magnetic material in the focal region with and without a magnet (used in figure 3) 3) Lysis rates (used in figures 4 and 8) 4) Acoustic energy detected (used in figures 7 and 8) 5) Clot debris sizing Microbubble-enhanced sonothrombolysis is a promising approach to increase the safety and efficacy of current pharmacological treatments for ischemic stroke. Maintaining therapeutic concentrations of microbubbles and drugs at the clot site however poses a challenge. …”
    Dataset
  12. 12

    'Hepitopes': A Database of HLA Class I Epitopes in Hepatitis B Virus (HBV) by Matthews, P

    Published 2016
    “…For these reasons, increased clinical and scientific scrutiny is being applied to develop new therapeutic approaches with an ultimate goal of achieving cure. …”
    Dataset