Revealing the intensity of turbulent energy transfer in planetary atmospheres by Cabanes, S, Espa, S, Galperin, B, Young, RMB, Read, PL

The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles. by Reynolds, C, Jones, C, Blohmke, C, Darton, T, Goudet, A, Sergeant, R, Maillere, B, Pollard, A, Altmann, D, Boyton, R

“…SseB is a secreted protein, part of the Espa superfamily, localized to the bacterial surface and forming part of the translocon of the type III secretion system (T3SS) encoded by Salmonella pathogenicity island 2. …”

Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium. by Simmons, C, Clare, S, Ghaem-Maghami, M, Uren, T, Rankin, J, Huett, A, Goldin, R, Lewis, D, MacDonald, T, Strugnell, R, Frankel, G, Dougan, G

“…Mice depleted of CD4(+) T cells also had diminished immunoglobulin G (IgG) and IgA antibody responses to two C. rodentium virulence-associated determinants, i.e., EspA and intimin, despite having a massively increased pathogen burden. …”

Central role for B lymphocytes and cd4+ t cells in immunity to infection by the attaching and effacing pathogen citrobacter rodentium by Simmons, C, Clare, S, Ghaem-Maghami, M, Uren, T, Rankin, J, Huett, A, Goldin, R, Lewis, D, Macdonald, T, Strugnell, R, Frankel, G, Dougan, G

“…Mice depleted of CD4^{+ T} cells also had diminished immunoglobulin G (IgG) and IgA antibody responses to two C. rodentium virulence-associated determinants, i.e., EspA and intimin, despite having a massively increased pathogen burden. …”

Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium by Ghaem-Maghami, M, Simmons, C, Daniell, S, Pizza, M, Lewis, D, Frankel, G, Dougan, G

“…Here we show that the LEE-encoded proteins EspA, EspB, Tir, and intimin are the targets of long-lived humoral immune responses in C. rodentium-infected mice. …”

Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium. by Ghaem-Maghami, M, Simmons, C, Daniell, S, Pizza, M, Lewis, D, Frankel, G, Dougan, G

“…Here we show that the LEE-encoded proteins EspA, EspB, Tir, and intimin are the targets of long-lived humoral immune responses in C. rodentium-infected mice. …”