Corneal biomechanical properties in primary open angle glaucoma and normal tension glaucoma. by Ang, G, Bochmann, F, Townend, J, Azuara-Blanco, A

“… PURPOSE: To determine and compare the corneal biomechanical properties between eyes with primary open angle glaucoma (POAG) and eyes with normal tension glaucoma (NTG). …”

Molecular characterisation of congenital glaucoma in a consanguineous Canadian community: a step towards preventing glaucoma related blindness by Martin, S

“…Glaucoma is a leading cause of irreversible blindness in Canada. …”

Normal-tension glaucoma and low cerebrospinal fluid pressure. by Yusuf, I, Ratnarajan, G, Kerr, R, Salmon, J

“…We thank Gallina and coauthors for their comments relating to our report of normal-tension glaucoma occurring prematurely in a 27-year-old male with chronic, recurrent intracranial hypotension. …”

The effect of socio-economic deprivation on severity of glaucoma at presentation. by Ng, W, Agarwal, P, Sidiki, S, McKay, L, Townend, J, Azuara-Blanco, A

“… OBJECTIVE: To evaluate the influence of socio-economic factors on severity of glaucoma at presentation METHODS: All newly diagnosed glaucoma patients at the University Hospitals-NHS, Aberdeen and South Glasgow University Hospitals-NHS, in 2006, were included. …”

Uveitic glaucoma and Rosai-Dorfman disease (sinus histiocytosis). by Maclaren, R, Hundal, K, Trittibach, P, Bloom, P

“…PURPOSE: To report a novel association of uveitic glaucoma with Rosai-Dorfman disease. METHODS: Case report. …”

Videoendoscope-guided fluorescein-assisted vitrectomy for phakic malignant glaucoma. by Chen, S, Salmon, J, Patel, C

“…Malignant glaucoma is a rare secondary glaucoma classically occurring after intraocular surgery in eyes with primary angle closure. …”

Remodeling of the connective tissue microarchitecture of the lamina cribrosa in early experimental glaucoma. by Roberts, MD, Grau, V, Grimm, J, Reynaud, J, Bellezza, A, Burgoyne, C, Downs, J

“…PURPOSE: To characterize the trabeculated connective tissue microarchitecture of the lamina cribrosa (LC) in terms of total connective tissue volume (CTV), connective tissue volume fraction (CTVF), predominant beam orientation, and material anisotropy in monkeys with early experimental glaucoma (EG). METHODS: The optic nerve heads from three monkeys with unilateral EG and four bilaterally normal monkeys were three dimensionally reconstructed from tissues perfusion fixed at an intraocular pressure of 10 mm Hg. …”

Screening tests for detecting open-angle glaucoma: systematic review and meta-analysis. by Mowatt, G, Burr, J, Cook, J, Siddiqui, M, Ramsay, C, Fraser, C, Azuara-Blanco, A, Deeks, J

“… PURPOSE: To assess the comparative accuracy of potential screening tests for open angle glaucoma (OAG). METHODS: Medline, Embase, Biosis (to November 2005), Science Citation Index (to December 2005), and The Cochrane Library (Issue 4, 2005) were searched. …”

MicroShunt versus trabeculectomy for surgical management of glaucoma: a retrospective analysis by Fu, MX, Normando, EM, Luk, SMH, Deshmukh, M, Ahmed, F, Crawley, L, Ameen, S, Vig, N, Cordeiro, MF, Bloom, PA

“…Primary endpoints included changes in intraocular pressure (IOP) and glaucoma medications. Secondary outcome measures included changes in retinal nerve fibre layer (RNFL) thickness, rates of complications, further theatre interventions, and the number of postoperative visits. …”

Conservative management of refractory steroid-induced glaucoma following anterior subtenon steroid injection. by Hanson, R, Downes, S

Determining possible shared genetic architecture between myopia and primary open-angle glaucoma by Iglesias, AI, Ong, JS, Khawaja, AP, Gharahkhani, P, Tedja, MS, Verhoeven, VJM, Bonnemaijer, PWM, Wolfs, RCW, Young, TL, Jansonius, NM, Craig, JE, Stambolian, D, Van Duijn, CM, Macgregor, S, Klaver, CCW

“…Purpose:To determine genetic correlations between common myopia and primary open-angle glaucoma (POAG). Methods:We tested the association of myopia polygenic risk scores (PRSs) with POAG and POAG endophenotypes using two studies: the Australian & New Zealand Registry of Advanced Glaucoma (ANZRAG) study comprising 798 POAG cases with 1992 controls, and the Rotterdam Study (RS), a population-based study with 11,097 participants, in which intraocular pressure (IOP) and optic disc parameter measurements were catalogued. …”

Motion discrimination of single targets: comparison of preliminary findings in normal subjects and patients with glaucoma. by Sahraie, A, Barbur, J, Edgar, D, Weiskrantz, L

“…Tested patients with glaucoma show reduced motion sensitivity and poor discrimination of motion direction. …”

Association of genetic variants with primary open-angle glaucoma among individuals with African ancestry by Hauser, M, Allingham, R, Aung, T, Van Duijn, C, al., E

“…<br/><strong>Importance: </strong>Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of African ancestry compared with European or Asian ancestry. …”

A common variant near TGFBR3 is associated with primary open angle glaucoma by Li, Z, Allingham, R, Nakano, M, Jia, L, Chen, Y, Ikeda, Y, Mani, B, Chen, L, Kee, C, Garway-Heath, D, Sripriya, S, Fuse, N, Abu-Amero, K, Huang, C, Namburi, P, Burdon, K, Perera, S, Gharahkhani, P, Lin, Y, Ueno, M, Ozaki, M, Mizoguchi, T, Krishnadas, S, Osman, E, Lee, M, Chan, A, Tajudin, L, Do, T, Goncalves, A, Reynier, P, Zhang, H, Bourne, R, Goh, D, Broadway, D, Husain, R, Negi, A, Su, D, Ho, C, Blanco, A, Leung, C, Wong, T, Yakub, A, Liu, Y, Nongpiur, M, Han, J, Hon, D, Shantha, B, Zhao, B, Sang, J, Zhang, N, Sato, R, Yoshii, K, Panda-Jonas, S, Ashley Koch, A, Herndon, L, Moroi, S, Challa, P, Foo, J, Bei, J, Zeng, Y, Simmons, C, Bich Chau, T, Sharmila, P, Chew, M, Lim, B, Tam, P, Chua, E, Ng, X, Yong, V, Chong, Y, Meah, W, Vijayan, S, Seongsoo, S, Xu, W, Teo, Y, Cooke Bailey, J, Kang, J, Haines, J, Cheng, C, Saw, S, Tai, E, Richards, J, Ritch, R, Gaasterland, D, Pasquale, L, Liu, J, Jonas, J, Milea, D, George, R, Al-Obeidan, S, Mori, K, Macgregor, S, Hewitt, A, Girkin, C, Zhang, M, Sundaresan, P, Vijaya, L, Mackey, D, Wong, T, Craig, J, Sun, X, Kinoshita, S, Wiggs, J, Khor, C, Yang, Z, Pang, C, Wang, N, Hauser, M, Tashiro, K, Aung, T, Vithana, E

“…Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex disease with a significant genetic contribution. …”

Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study by Virgili, G, Michelessi, M, Cook, J, Boachie, C, Burr, J, Banister, K, Garway-Heath, D, Bourne, R, Asorey, A, Ramsay, C, Azuara-Blanco, A

“…<p><strong>Background/Aims</strong> To assess the diagnostic performance of retinal nerve fibre layer (RNFL) data of optical coherence tomography (OCT) for detecting glaucoma.</p> <p><strong>Methods</strong> Secondary analyses of a prospective, multicentre diagnostic study (Glaucoma Automated Tests Evaluation (GATE)) referred to hospital eye services in the UK were conducted. …”

Juvenile-onset normal tension glaucoma from chronic, recurrent low cerebrospinal fluid pressure. by Yusuf, I, Ratnarajan, G, Kerr, R, Salmon, J

“… <h4>Introduction</h4> <p>The evidence for low cerebrospinal fluid pressure (CSFP) as a key parameter in the pathogenesis of glaucoma is increasing. Primate models have demonstrated the onset normal tension glaucoma (NTG) from experimentally induced chronic intrathecal hypotension; an approach not possible in human subjects.…”

Microperimetry and optical coherence tomography imaging in the fellow eye of patients with unilateral focal ischaemic glaucoma by Yusuf, I, Jolly, J, Ratnarajan, G, Salmon, J

“…<strong>Purpose</strong> To determine whether microperimetry or optical coherence tomography (OCT) imaging can detect early disease in the fellow eye of patients with unilateral focal ischaemic glaucoma. <strong>Methods</strong> Thirty-seven consecutive adult patients with unilateral focal ischaemic glaucoma with a unilateral split-fixation visual field defect on standard automated perimetry (SAP) with normal SAP in the fellow eye were selected. …”

Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations by Bonnemaijer, P, Iglesias, A, Nadkarni, G, Sanyiwa, A, Hassan, H, Cook, C, Giga Study Group, Simcoe, M, Taylor, K, Schurmann, C, Belbin, G, Kenny, E, Bottinger, E, Van De Laar, S, Wiliams, S, Akafo, S, Ashaye, A, Zangwill, L, Girkin, C, Ng, M, Rotter, J, Weinreb, R, Li, Z, Allingham, R, Eyes Of Africa Genetics Consortium, Nag, A, Hysi, P, Meester-Smoor, M, Wiggs, J, Neighborhood Consortium, Hauser, M, Hammond, C, Lemij, H, Loos, R, Van Duijn, C, Thiadens, A, Klaver, C

“…Primary open angle glaucoma (POAG) is a complex disease with a major genetic contribution. …”

Trends in rates of primary angle closure glaucoma and cataract surgery in England from 1968 to 2004. by Keenan, T, Salmon, J, Yeates, D, Goldacre, M

“…The aim of this study was to examine trends over time in rates of primary angle closure glaucoma (PACG) in England, and to compare these rates with rates of cataract surgery. …”

Selective laser trabeculoplasty in primary open-angle glaucoma: primary versus secondary treatment outcomes by Goosen, E, Visser, L, Sartorius, B

“…<br><strong>Objective: <br></strong>To compare the outcomes of selective laser trabeculoplasty (SLT) on treatmentnaive, primary open-angle glaucoma (POAG) patients with those of SLT on patients previously treated medically and/or surgically. …”