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Early steps in Xenopus neural determination : cloning and analysis of opl
Published 2009Get full text
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Notch signalling in Xenopus laevis haematopoietic stem cell programming
Published 2013“…Here, the relatively slow development and the spatial separation of definitive haematopoiesis from primitive haematopoiesis in Xenopus laevis has been exploited to reveal the first defect of reduced notch signalling in the Xenopus DA.…”
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The response of synthetic 4-hydroxybenzoic acid on kv1.4 potassium channel subunit expressed in xenopus laevis oocytes
Published 2016“…In this study, the response of synthetic 4-hydroxybenzoic acid was tested on Kv1.4 potassium channel that was expressed in Xenopus laevis oocytes as the model system. Kv1.4 is a rapidly inactivating Shaker-related member of the voltage-gated potassium channels with two inactivation mechanisms; the fast N-type and slow C-type. …”
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Electrophysiological analysis of the epithelial H+/oligopeptide transporter, PepT1
Published 2001Subjects:Thesis -
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The role of BMP signalling in HSC ontogeny
Published 2013“…</p> <p>Taken together, the findings presented here demonstrate an essential post-gastrulation role of BMP signalling and Evi3 for programming HSCs in <em>Xenopus</em>.</p>…”
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The emergence of visual responses in the developing retinotectal system in vivo
Published 2013“…I show that the eyes of developing Xenopus larvae are hyperopic at the onset of vision, but rapidly grow towards correct vision. …”
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Studies on nucleocytoplasmic relationships during differentiation in vertebrates (1961)
Published 1961“…Nuclear transplantation in Xenopus laevis is carried out by a similar method to that of Briggs and King for Rana pipiens. …”
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Modelling the collective migration of neural crest cells
Published 2021“…For example, chick cranial neural crest cells are understood to be guided by a cell-induced chemotactic gradient and their migration occurs within a growing tissue, whilst in Xenopus, cranial neural crest cells are understood to be guided by co-attractive and co-repulsive intercellular interactions in the absence of growth. …”
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Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
Published 2012“…Both crude and essential oil were tested on the Xenopus laevis oocytes that comprised of GABA (A) receptors α1β2γ2s subtype. …”
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Structural studies of the nucleosome, assembled with different histones, DNA fragments and HMGN proteins, and derivatized with ruthenium anticancer agents
Published 2013“…Furthermore, we did preliminary studies on the interaction of ruthenium-based compounds with Xenopus laevis and human nucleosomes, and showed that both gave satisfying results. …”
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Prediction, design and characterisation of metal binding sites in antibodies
Published 1992“…The final model was used as a basis for site-directed mutagenesis and mutant antibodies were produced using a Xenopus laevis oocyte expression system. Antigen binding studies showed the mutants to have an affinity for lysozyme equivalent to the parent antibody, while subsequent metal binding experiments have shown the new site to be capable of binding the transition metals cobalt, nickel, copper, zinc and cadmium.…”
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Characterization of the biological properties of FGF-9
Published 1996“…</p> <p>Mouse <em>Fgf9</em> exhibits a high level of sequence conservation with the human, rat and <em>Xenopus</em> counterparts. Of note is the lack of a hydrophobic signal peptide at the N-terminus of the coding sequence. …”
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The isolation and characterization of orbiviruses from ticks (ixodes uriae)
Published 1984“…The viruses replicated in suckling mouse brain, chick embryo fibroblasts, Vero and BHK-21 cells, but not in Xenopus cells. By virtue of their morphology in infected cells, physicochemical properties and reactions in complement fixation tests, they were identified as Kemerovo serogroup viruses belonging to the Great Island Complex (Orbivirus:Reoviridae). …”
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Mechanical integration between cytoplasmic networks during cytokinesis
Published 2023“…These broad questions were addressed in two systems: eggs of the frog Xenopus laevis, and JCVI-syn3.0, a genomically minimized bacterium derived from Mycoplasma mycoides. …”
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Structural studies of Norrin dependent Wnt/beta-catenin signaling
Published 2014“…Structural comparison with <em>Xenopus</em> Wnt8 in complex with mouse Fz8-CRD provides molecular insights for our understanding of ligand-receptor binding specificity and promiscuity, which has important implications for developing therapeutic strategies against Norrin dependent retinal disorders, and cancers caused by abnormal Wnt signaling.…”
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The extreme anterior domain coordinates brain and craniofacial development
Published 2018Get full text
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