Epigenetic regulation of the myeloid cell lineage by Pliuskys, L

Identification of epigenetic regulators of RNA editing mechanisms by Buss, G

Epigenetic regulation of postnatal subventricular zone development by Sun, B

“…</p> <p>To conclude, I discovered two interacting epigenetic regulators that control postnatal SVZ NSC and neurogenesis.…”

Epigenetic regulation of chronological and replicative longevity in Saccharomyces cerevisiae by Ayling, J

“…While it has been proposed that epigenetic regulation controls these shifts, evidence remains incomplete. …”

Nucleic acid structures as transcriptional and epigenetic regulators in health and disease by da Silva Cravo, L

“…</p> <p>In the first part of this thesis, the transcriptional and epigenetic regulation of the HTT gene in HD is investigated. …”

The role of Polycomb-mediated epigenetic regulation in embryonic stem cell differentiation by Thornton, Seraphim R

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Systems modeling and network inference for genetic and epigenetic regulation of gene expression by Chen, Haifen

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Investigating the epigenetic regulation of the eukaryotic centromere by the segregase enzyme p97 by East, S

Heterogeneity within colorectal cancer cell lines and epigenetic regulation of CD24 by Ibn Ayub, M

Understanding the epigenetic regulation of stem cell fate in planarians using functional genomics by Sridhar, DL

“…This work aims to understand the epigenetic regulation of stem cell fate in planarians using an array of next-generation sequencing methods.…”

Identifying epigenetic regulators of survival motor neuron protein to treat spinal muscular atrophy by Kordala, A

“…These results provide a new insight into epigenetic regulation of SMN and PRMT function in splicing and justify moving forward with MS023 preclinical development as an add-on therapy for SMA.…”

Genetic and epigenetic regulation of the cell wall glycoproteins, Flo10p and Flo11p, generate phenotypic variation in S. cerevisiae by Halme, Adrian Jones, 1971-

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Studies of epigenetic cytosine, 5- hydroxymethylcytosine : effects on duplex thermostability and chemical detection methods by Wu, Qiong

“…Cytosine methylation is a critical mechanism for epigenetic regulation on the molecular level, which has profound impacts on heritable gene silencing and plays an essential role in mammalian cell development. …”
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Investigating the effect of hypoxia on the JmjC histone lysine demethylase KDM4A by Hancock, R

“…<p>The JmjC-histone lysine demethylases (JmjC-KDMs) are epigenetic regulators responsible for the demethylation of methylated lysine residues on the <em>N</em>-terminal histone tails. …”

Studies of histone modifications in yeast and humans by Hsu, K

“…<p>Epigenetic regulation is a complex biological process that has influence on the structure of chromatin and impacts on the regulation of DNA-associated events, including transcription, DNA replication, and DNA damage repair. …”

Development of biochemical tools to characterise human H3K27 histone demethylase JmjD3 by Che, KH

“…<p>Covalent modifications of histone tails play essential roles in mediating chromatin structure and epigenetic regulation. JmjD3 is a JumonjiC domain containing histone demethylase, belongs to the KDM6 subfamily, and catalyses the removal of methyl groups on methylated lysine 27 on histone 3 (H3K27), a critical mark to promote polycomb mediated repression and gene silencing. …”

Development of ligands for the TRIM33 bromodomain by See, L

“…Given the involvement of epigenetics in diseases, including cancer, epigenetic regulation presents opportunities for the development of novel therapeutics. …”

Chemical probes for histone lysine demethylases by Gerken, P

“…Chapter one of this thesis introduces the role of histone lysine demethylases (KDMs) in the epigenetic regulation of gene expression and discusses the value of chemical probes as tools to study these enzymes. …”

Structural and functional studies of chromatin modifying enzymes by Walport, L

“…<p>Epigenetic regulation is a complex process involving the interplay of multiple different cellular factors. …”

Illuminating the function of a master regulator of Caulobacter crescentus gene expression by Yuan, Andy H. (Andy Han)

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