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Peptides as therapeutics
Published 2011“…<p>Peptides have attracted increasing attention as therapeutics in recent years, at least partially as a consequence of the widespread acceptance of protein therapeutics; but also as possible solutions to problems such as short half-life and delivery of molecules, and as therapeutics in their own right. …”
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RNA-based therapeutics for Alzheimer's disease
Published 2015“…Currently, there are no disease-modifying therapeutic interventions available. This thesis describes the development and delivery of novel RNA-based therapeutics for AD.…”
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Inhibitory superagonistic antibodies as novel therapeutics
Published 2023“…Overall, the thesis strengthens the idea that there is considerable scope for generating a large variety of potentially useful therapeutic agonists.…”
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Cavitation-enhanced delivery of therapeutics to solid tumors
Published 2011“…The solid tumor microenvironment presents several physiological abnormalities which reduce the uptake of intravenously administered therapeutics, including leaky, irregularly spaced blood vessels, and a pressure gradient which resists transport of therapeutics from the bloodstream into the tumor. …”
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Factors affecting the commercialization of cellular based therapeutics
Published 2018“…<p>Introduction</p> <p>Cell based therapeutics represent a commercially and clinically important treatment modality that offers a transformative approach to managing untreatable diseases. …”
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Boronic acid and nitrofuranyl derivatives as potential therapeutics
Published 2021“…Last but not least, it is hoped that a handful of these potentially novel therapeutics could further be developed into leads or drug candidates either in Oxford or elsewhere in an attempt to tackle the ever-increasing antibacterial resistance. …”
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The modification of insulin for therapeutic purposes
Published 1978“…<p> First this thesis outlines the historical background and current status of diabetes therapeutics. This includes prolonged action preparations, oral hypoglycaemic agents, approaches to peroral insulin therapy and methods of insulin modification, with emphasis on derivatives of clinical interest.…”
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Synthetic biology approaches for engineering bacteria as living therapeutics
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Tumor-penetrating delivery of small interfering RNA therapeutics
Published 2012Get full text
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Novel lipophilic cations for delivery of mitochondria-acting therapeutics
Published 2018“…It is, therefore, necessary during the design of lipophilic cation as pro-drugs and drug transporters, to investigate the factors that can minimise the therapeutic concentration and improve its delivery ability. …”
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Identification and characterisation of candidate monoclonal antibody Ebolavirus therapeutics
Published 2021Subjects: “…Monoclonal antibodies--Therapeutic use…”
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Statistical analysis of the nexus between dietary habits and practices with clinical outcome in Saudi patients with type 2 diabetes
Published 2019Subjects: “…RM Therapeutics. Pharmacology…”
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Developing and validating a new comprehensive glucose-insulin pharmacokinetics and pharmacodynamics model
Published 2013Subjects: “…RM Therapeutics. Pharmacology…”
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Pengaruh Kombinasi Fraksi Tak Larut n-Heksan Ekstrak Etanolik Herba Sambiloto (Andrographis paniculata (Burm.f.) Nees) dan Fraksi Larut Etil Asetat Ekstrak Etanolik Propolis Terhad...
Published 2013Subjects: “…Clinical Pharmacology and Therapeutics…”
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The influence of genetic polymorphisms of CYP3A on the pharmacokinetic variation and clinical outcomes of tacrolimus in a cohort of patients / Mohd Rahimi Muda
Published 2014Subjects: “…RM Therapeutics. Pharmacology…”
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