Nongenetic engineering of subcellular targeted therapeutic agents to facilitate precise cell activity manipulation by Do, Cong Thang

“…Upon specific uptake and cleavage of the furin peptide moiety, the free azide sugar is released after self-immolation of the linker. The unnatural sugar subsequently undergoes a metabolic process to express clickable azide functional group on the cancer cell surface. …”
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Biomimetic peptide coacervates for intracellular delivery and release of biomacromolecules by Sun, Yue

“…Based on this altered phase behavior, a strategy was devised to allow for the controlled release of encapsulated therapeutics using a disulfide-based self-immolative modification on the inserted Lys residue. …”
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