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Chromatin topology defines cell identity and phenotypic transition in human cancer and fungal pathogen
Published 2020“…Higher-order chromatin organization plays an important role in epigenetic regulation of gene expression. Chromatin topology has been increasingly recognized to define cellular identity. …”
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Thesis-Doctor of Philosophy -
2
Differential metabolic profiles mediated SLC1A2 confer resistance in glioblastoma therapies : stratification goals and implementation
Published 2020“…Enrichment of our ROS signature with global epigenetic regulator profiles identified EZH2, the catalytic subunit of Polycomb repressive complex 2 (PRC2) that is frequently dysregulated in GBM tumors. …”
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Thesis-Doctor of Philosophy